NCT05392062

Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respiratory Failure Due to COVID-19. A Multicenter Prospective Study.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: CHU de Reims · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The pathophysiology of SARS-COV-2 related respiratory disease is still poorly understood, especially in its most severe form called acute respiratory distress syndrome (ARDS). In this case, very few studies have investigated changes in gas exchange during COVID-19 progression in spontaneously breathing patients. The investigators purpose in this study to explore the pathophysiology of gas exchange and time course changes in spontaneously breathing patients with acute respiratory failure due to COVID-19. Moreover, our aim is to identify early markers associated with worsening respiratory failure and requiring endotracheal intubation.

Conditions

• Respiratory Insufficiency

Interventions

Type	Name	Description
OTHER	Pathophysiology of gas exchange	Exploration of pathophysiology of gas exchange

Timeline

• Start date: 2021-06-09
• Primary completion: 2023-01-15
• Completion: 2023-04-15
• First posted: 2022-05-26
• Last updated: 2024-12-13

Locations

1 site across 1 country: France