NCT00453726

Brain Natriuretic Peptide (BNP) Levels in Patients in Non Invasive Mechanical Ventilation

Evaluation of BNP in Patients With Severe Acute Respiratory Failure Requiring Non Invasive Mechanical Ventilation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Ospedale S. Giovanni Bosco · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to evaluate variation of BNP in non invasive mechanical ventilated patients with severe acute respiratory failure.

Detailed description

The aim of the study is to evaluate in patients with severe acute respiratory failure requiring non invasive mechanical ventilation BNP levels at admission and during the following 24 hours during non invasive mechanical ventilation (Non Invasive Positive Pressure Ventilation or Continuous positive airway pressure). Because in patients affected by acute respiratory failure it is often difficult to distinguish if the disease precipitating the respiratory failure is a cardiac disease or a lung disease, aim of the present study is to evaluate the discriminating role that BNP could have in this group of patients; evaluation will be completed, once obtained clinical stabilisation, with an echocardiography and respiratory functional test.

Conditions

• Respiratory Insufficiency

Interventions

Type	Name	Description
PROCEDURE	Non invasive mechanical ventilation

Timeline

• Start date: 2006-05-01
• Completion: 2009-07-01
• First posted: 2007-03-29
• Last updated: 2009-10-05

Locations

1 site across 1 country: Italy