NCT04368325

Low Creatinine Level and Respiratory Failure

A Correlation of Low Serum Creatinine Levels and Respiratory Function in the Mechanically Ventilated Patients in the Intensive Care Unit

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 107 (actual)
• Sponsor: Osijek University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Low creatinine levels may be a sign of muscle atrophy or weakness, and therefore predictive for respiratory insufficiency in the Intensive care unit (ICU) patients. The investigators compared the outcomes of participants with low creatinine levels with subsequent ICU participants admitted into ICU in the tertiary hospital.

Detailed description

The investigators have found a total of 46 participants with low creatinine levels and compared their outcome data with a group of participants with normal or high creatinine levels (control group, N=61). Low creatinine was defined as values of ≤40 μmol/L. Demographic data, type of admission (medical vs. surgical), hemoglobin values, CRP, and ventilator days were compared. A statistical analysis was performed using chi square and T-test.

Conditions

• Intensive Care Unit
• Respiratory Insufficiency
• Muscle Weakness

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Serum creatinine levels	Comparison of treatment length using mechanical ventilaton, length of stay in ICU, survival between two groups

Timeline

• Start date: 2015-05-17
• Primary completion: 2016-11-04
• Completion: 2017-06-16
• First posted: 2020-04-29
• Last updated: 2020-04-29

Locations

1 site across 1 country: Croatia