Trials / Sponsors / NICHD Neonatal Research Network
NICHD Neonatal Research Network
Network · 63 registered clinical trials — 5 currently recruiting.
| Status | Trial | Phase | Started |
|---|---|---|---|
| Not Yet Recruiting | Continued Pressure for Alveolar Protection (CPAP Trial) Bronchopulmonary Dysplasia (BPD) | N/A | 2026-05-31 |
| Recruiting | Neonatal Platelet Transfusion Threshold Trial Thrombocytopenia, Neonatal, Platelet Transfusion | N/A | 2025-06-13 |
| Recruiting | Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial Post-ligation Cardiac Syndrome | Phase 3 | 2025-06-13 |
| Active Not Recruiting | The Budesonide in Babies (BiB) Trial Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome, Prematurity; Extreme | Phase 3 | 2021-04-01 |
| Active Not Recruiting | Cycled Phototherapy Hyper Bilirubinemia, Premature Infant | N/A | 2020-07-16 |
| Terminated | Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial Apnea of Prematurity | Phase 3 | 2019-02-27 |
| Active Not Recruiting | Management of the PDA Trial Infant, Premature, Patent Ductus Arteriosus, Infant, Newborn, Diseases | Phase 3 | 2019-02-22 |
| Completed | Milrinone in Congenital Diaphragmatic Hernia Congenital Diaphragmatic Hernia, Persistent Pulmonary Hypertension of the Newborn, Hypoxemic Respiratory Failure | Phase 2 | 2017-10-24 |
| Completed | Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants Neurocognitive, Neuroprotective, Neonatal | Phase 3 | 2017-09-20 |
| Completed | Preemie Hypothermia for Neonatal Encephalopathy Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain | N/A | 2015-05-01 |
| Completed | Early-Onset Sepsis an NICHD/CDC Surveillance Study Infant, Newborn, Diseases, Early Onset Neonatal Sepsis, Early-Onset Meningitis | — | 2015-04-01 |
| Completed | Incubator Weaning of Moderately Preterm Infants Infant, Newborn, Infant, Moderate Preterm | N/A | 2015-02-01 |
| Completed | Hydrocortisone for Term Hypotension Infant, Newborn, Diseases, Cardiovascular Insufficiency | Phase 3 | 2014-06-19 |
| Terminated | Inositol to Reduce Retinopathy of Prematurity Retinopathy of Prematurity (ROP) | Phase 3 | 2014-04-17 |
| Completed | Transfusion of Prematures Trial Infant, Newborn, Diseases, Infant, Extremely Low Birth Weight, Infant, Small for Gestational Age | N/A | 2012-12-01 |
| Completed | Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants Infant, Newborn, Infant, Small for Gestational Age, Infant, Extremely Low Birth Weight | Phase 3 | 2012-08-01 |
| Completed | Generic Database of Moderate Preterm Infants Infant, Newborn, Infant, Moderate Preterm | — | 2012-03-01 |
| Terminated | Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) Prematurity, Respiratory Insufficiency, Pulmonary Hypertension | Phase 2 | 2011-11-01 |
| Completed | Hydrocortisone for BPD Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight | Phase 3 | 2011-08-11 |
| Completed | Vitamin E for Extremely Preterm Infants Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight | Phase 1 | 2010-10-01 |
| Terminated | Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE) Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain | N/A | 2010-09-01 |
| Completed | Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | N/A | 2010-01-01 |
| Completed | Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 | 2010-01-01 |
| Completed | Cerebral Function Monitoring in Premature Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 2009-07-01 |
| Completed | Early Blood Pressure Management in Extremely Premature Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 1 | 2009-07-01 |
| Completed | Hypotension in Neonates Infant, Newborn, Hypotension, Blood Pressure | — | 2009-04-01 |
| Withdrawn | Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension | Phase 2 | 2008-05-01 |
| Completed | Late Hypothermia for Hypoxic-Ischemic Encephalopathy Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain | N/A | 2008-04-01 |
| Completed | Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 | 2006-06-01 |
| Completed | Early-Onset Sepsis Surveillance Study Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 2006-02-01 |
| Completed | Physiologic Definition of Bronchopulmonary Dysplasia Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 2005-05-01 |
| Completed | Surfactant Positive Airway Pressure and Pulse Oximetry Trial Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age | Phase 3 | 2005-02-01 |
| Completed | Immunogenicity of PCV-7 Vaccine in VLBW Infants Pneumococcal Infections, Streptococcus Pneumoniae, Infant, Newborn | — | 2004-07-01 |
| Completed | Early Diagnosis of Candidiasis in Premature Infants Infection, Candida, Candidiasis | — | 2004-03-01 |
| Completed | Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn | Phase 3 | 2002-09-01 |
| Completed | Delivery Room CPAP in Extremely Low Birth Weight Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 1 / Phase 2 | 2002-07-01 |
| Completed | Observational Study of Surgical Treatment of Necrotizing Enterocolotis Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 2001-03-01 |
| Completed | Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | N/A | 2001-03-01 |
| Terminated | Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 3 | 2001-01-01 |
| Completed | Delayed Cord Clamping in VLBW Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 1 / Phase 2 | 2000-06-01 |
| Terminated | Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants Infant, Newborn, Respiratory Distress Syndrome, Respiratory Insufficiency | Phase 3 | 2000-05-01 |
| Completed | Whole-Body Cooling for Birth Asphyxia in Term Infants Infant, Newborn, Hypoxia-Ischemia, Brain | Phase 3 | 1999-10-01 |
| Completed | Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 3 | 1999-07-01 |
| Completed | Inflammatory Cytokines Associated With Perinatal Brain Injury Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1999-07-01 |
| Terminated | Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome | Phase 3 | 1998-08-01 |
| Terminated | Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (S Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Infant, Newborn | Phase 3 | 1998-02-01 |
| Completed | The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 / Phase 3 | 1997-08-01 |
| Completed | In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1996-07-01 |
| Completed | Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 1 / Phase 2 | 1996-01-01 |
| Terminated | Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome | Phase 3 | 1995-10-01 |
| Completed | Growth Observational Study Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1994-08-01 |
| Completed | Development of Standards for the New Ballard Maturation Score Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1994-06-01 |
| Completed | Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 / Phase 3 | 1994-02-01 |
| Completed | Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) Infant, Very Low Birth Weight, Infant, Premature, Ductus Arteriosus, Patent | Phase 3 | 1993-11-01 |
| Completed | Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1993-10-01 |
| Completed | The Maternal Lifestyle Study (MLS) Cocaine, Substance Abuse, Infant, Newborn | — | 1993-05-01 |
| Recruiting | Follow-up Visit of High Risk Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1993-04-01 |
| Completed | Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 3 | 1993-02-01 |
| Completed | Dexamethasone Therapy in VLBW Infants at Risk of CLD Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 3 | 1992-09-01 |
| Completed | Prediction of Jaundice in Term Infants Infant, Newborn, Jaundice | — | 1991-11-01 |
| Completed | Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 / Phase 3 | 1991-01-01 |
| Completed | Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | Phase 2 / Phase 3 | 1988-01-01 |
| Recruiting | Generic Database of Very Low Birth Weight Infants Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age | — | 1987-04-01 |