NCT01383213

Helmet Continuous Positive Airway Pressure (CPAP) Versus Oxygen Venturi in Severe Acute Respiratory Failure in Pneumonia

A Prospective, Randomized, Controlled Trial to Evaluate the Efficacy of CPAP Delivered by Helmet in Comparison With Oxygen Therapy by Venturi Mask in Severe Acute Respiratory Failure Caused by Pneumonia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the efficacy of CPAP application by a helmet and O2 administration by a Venturi mask in terms of achievement of criteria for endotracheal intubation during severe acute respiratory failure caused by pneumonia

Detailed description

Pneumonia is one of the commonest causes of hospitalised acute respiratory failure with a mortality rate up to 30%. Continuous Positive Airway Pressure (CPAP) has ben recently proved to be effective. To date, however, no prospective randomised study has been published on the comparison between CPAP and O2 administration by Venturi mask for the treatment of severe acute respiratory failure in patients with pneumonia. .

Conditions

• Pneumonia
• Respiratory Insufficiency

Interventions

Type	Name	Description
OTHER	Oxygen therapy	patient in group oxygen therapy by Venturi Mask will be treated with oxygen until reaching clinical stability, or criteria of endotracheal intubation
OTHER	Helmet CPAP	patient in group CPAP will be treated with CPAP until reaching clinical stability, or criteria of endotracheal intubation

Timeline

• Start date: 2010-02-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2011-06-28
• Last updated: 2014-02-14
• Results posted: 2014-02-14

Locations

1 site across 1 country: Italy