| Not Yet Recruiting | Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses. Gingival Inflammation | Phase 4 | 2026-05-01 |
| Not Yet Recruiting | A Study to Investigate Stannous Fluoride Containing Toothpaste on Antibacterial Effects in the Different Regio Plaque, Gingivitis | Phase 3 | 2026-05-01 |
| Not Yet Recruiting | Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding Plaque, Dental, Gingivitis | Phase 3 | 2026-04-01 |
| Not Yet Recruiting | Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Oral Malodor | Phase 3 | 2026-04-01 |
| Active Not Recruiting | Clinical Study to Assess the Efficacy of New Toothpaste Containing SnF as Compared to Colgate Cavity Protectio Enamel Erosion | Phase 3 | 2026-03-03 |
| Recruiting | Bacterial Reduction for a Manual Toothbrush With a 360-Degree Mouth Cleaner Design Versus a Standard Toothbrus Bacterial Load Reduction | Phase 3 | 2026-03-01 |
| Recruiting | 6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established P Gingivitis, Dental Plaque Accumulation | Phase 4 | 2026-01-28 |
| Recruiting | Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen Plaque | Phase 3 | 2026-01-26 |
| Active Not Recruiting | Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Proble Gingivitis, Plaque, Dental | Phase 3 | 2025-12-01 |
| Completed | Efficacy of a Toothpaste Containing Hydrogen Peroxide as Compared to a Regular Fluoride Toothpaste Without Hyd Whitening | Phase 3 | 2025-11-20 |
| Completed | Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System Health Adult Subjects | Phase 3 | 2025-10-31 |
| Completed | The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Plaque, Gingivitis | Phase 3 | 2025-10-14 |
| Completed | Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model Demineralization, Remineralization, Dental Cavity | Phase 3 | 2025-10-09 |
| Completed | Clinical Investigation of PerioGard (Test) Regimen Gingivitis | Phase 3 | 2025-08-18 |
| Completed | To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpa Sensitivity, Tooth | Phase 3 | 2025-08-18 |
| Completed | Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hyperse Hypersensitivity | Phase 3 | 2025-07-14 |
| Completed | Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis Dental Plaque, Gingivitis | Phase 4 | 2025-07-07 |
| Completed | Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Too Dentin Hypersensitivity | Phase 3 | 2025-05-10 |
| Completed | Clinical Investigation of Bleeding Reduction Efficacy on Toothpaste Containing 1.05% Chitosan Bleeding Gum, Gingivitis | N/A | 2025-04-29 |
| Completed | Clinical Study to Evaluate the Tooth Whitening Efficacy Whitening | Phase 3 | 2025-04-25 |
| Completed | Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Pla Gingivitis, Gingivitis and Periodontal Diseases, Gingival Disease | Phase 3 | 2025-03-24 |
| Completed | Evaluation of the Anti-cavity Efficacy of Three Dentifrices Using an Intra-oral Enamel Demineralization - Remi Enamel Lesions, Demineralization, Tooth, Remineralization | Phase 3 | 2025-03-13 |
| Completed | Dentinal Hypersensitivity Reduction Efficacy Study Sensitivity, Tooth | Phase 3 | 2025-03-04 |
| Completed | Clinical of Hypersensitivity Reduction Efficacy on Two Toothpastes Hypersensitivity | Phase 3 | 2024-10-08 |
| Completed | Clinical Study to Assess the Efficacy of Professional Tooth Whitening Maintenance System Staining | N/A | 2024-10-07 |
| Completed | Clinical Efficacy of the Combined Effect of Oral Irrigator and Chemicals (0.075% CPC) Dental Plaque, Dental Plaque Induced Gingivitis, Dental Plaque and Gingivitis | Phase 3 | 2024-09-30 |
| Completed | Efficacy of Manual Toothbrushes in Removing Tooth Stains Tooth Discoloration | Phase 3 | 2024-09-23 |
| Completed | Clinical Research Study to Assess the Efficacy of Two Brushing Regimens Dental Plaque, Gingivitis | Phase 3 | 2024-09-23 |
| Completed | Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brus Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases | Phase 3 | 2024-09-17 |
| Completed | Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis Red Gingival Bleeding, Plaque Induced Gingival Disease, Gingivitis and Periodontal Diseases | Phase 3 | 2024-09-16 |
| Completed | Assessing the Colgate Assist Handle Toothbrush in Individuals With Impairment of Hand Movement. Movement Disorders and Physical Impairments | — | 2024-09-01 |
| Completed | To Validate Changes in Knowledge, Attitudes and Practices (KAPs) Related to the Know Your OQ Initiative and to Literacy-language Intervention | — | 2024-08-03 |
| Completed | Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis Plaque, Dental, Gingivitis | Phase 2 | 2024-07-26 |
| Completed | Arginine Plaque Metabolism Pilot Clinical Study Plaque, Dental | Phase 3 | 2024-07-24 |
| Completed | Evaluation of the Know Your OQ™ Oral Health Literacy Tool in an Indian Population Oral Health Literacy | — | 2024-05-20 |
| Completed | The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protec Plaque, Gingivitis | Phase 3 | 2024-04-22 |
| Completed | Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlli Plaque, Dental, Gingivitis | Phase 3 | 2024-04-15 |
| Completed | Anti-gingivitis Mouthrinse Gingivitis | Phase 3 | 2024-03-06 |
| Completed | Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort Areas Plaque, Dental | Phase 3 | 2024-02-19 |
| Completed | Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Gingivitis, Plaque | Phase 3 | 2024-01-22 |
| Completed | Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101 Caries,Dental | Phase 1 | 2023-11-27 |
| Completed | Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing Palatal Wound | N/A | 2023-07-15 |
| Completed | Clinical Study on Malodor Oral Malodor | Phase 3 | 2023-06-01 |
| Completed | Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva Plaque, Dental | Phase 3 | 2023-03-08 |
| Completed | Documenting Toothbrushing Experiences of Caregivers Who Care for Children With Autism Spectrum Disorders ASD I, ASD2 | — | 2022-08-23 |
| Completed | Effect of Mouthwash in Reducing the Symptoms Associated With Flu and Cold Viruses Healthy | Phase 3 | 2022-06-05 |
| Completed | Investigate a Varnish to Protect From Erosive Toothwear Tooth Erosion | Phase 3 | 2022-04-08 |
| Completed | Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste. Gingivitis, Plaque | Phase 2 | 2022-01-18 |
| Completed | Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Im Gingivitis | Phase 3 | 2021-10-18 |
| Completed | A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems Plaque, Gum Disease | Phase 3 | 2021-03-08 |
| Completed | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifri Dental Caries | Phase 2 | 2021-01-21 |
| Completed | Measurement of Viral Load Reduction in the Oral Cavity After a Regimental Use of OC Toothpaste Products Covid19 | Phase 3 | 2020-12-28 |
| Completed | Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria Saliva and Bioaerosol Contamination Healthy | Phase 2 | 2020-11-16 |
| Completed | Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria in Saliva and Bioaerosol Contaminat Healthy | Phase 2 | 2020-10-08 |
| Completed | Dentinal Hypersensitivity Reduction Dentinal Hypersensitivity | Phase 3 | 2020-09-28 |
| Completed | Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste Gingivitis, Plaque, Dental | Phase 3 | 2020-08-18 |
| Completed | Clinical Research Study to Evaluate the Stain Removal Efficacy Tooth Stain Removal | Phase 3 | 2020-07-27 |
| Completed | Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbru Gingivitis, Plaque, Dental | N/A | 2019-04-30 |
| Completed | 2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste Dental Caries | Phase 3 | 2019-04-15 |
| Completed | Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste Gingivitis | Phase 4 | 2019-03-06 |
| Completed | Clinical Study to Assess Therapeutic Delay and Resolution of Induced Gingivitis Gingivitis | Phase 4 | 2018-12-22 |
| Completed | A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothp Oral Malodor | Phase 3 | 2017-12-21 |
| Completed | Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples Plaque | Phase 2 | 2017-10-06 |
| Completed | The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Avai Dental Plaque, Gingivitis | Phase 3 | 2017-05-25 |
| Completed | Efficacy of Toothpaste Containing 0.454% Stannous Fluoride as Compared to a Regular Fluoride Toothpaste Contai Calculus, Dental | Phase 2 / Phase 3 | 2017-05-17 |
| Withdrawn | Assessment of Prevident Sodium Fluoride 1.1% Toothpaste Using an Intra-oral Remineralization-demineralization Dental Caries | Phase 2 | 2016-03-01 |
| Completed | Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodo Periodontal Disease, Systemic Inflammatory Markers | Phase 4 | 2015-06-01 |
| Withdrawn | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Stu Dental Caries | Phase 2 | 2015-04-01 |
| Completed | The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis Dental Plaque and Gingivitis | Phase 2 | 2014-12-01 |
| Completed | The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Dental Plaque, Gingivitis | Phase 3 | 2014-07-01 |
| Completed | Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-co Dental Plaque, Gingivitis | Phase 4 | 2014-06-01 |
| Completed | The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingiv Dental Plaque, Gingivitis | Phase 4 | 2014-06-01 |
| Completed | Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria Oral Bacteria Levels in the Mouth | Phase 4 | 2014-01-01 |
| Completed | Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste Dental Plaque, Gingivitis | Phase 4 | 2013-03-01 |
| Completed | Compare Anti-inflammatory Dentifrices Gingivitis | Phase 4 | 2009-02-01 |
| Completed | The Efficacy of a Toothpaste to Reduce Sensitivity Dentin Hypersensitivity | Phase 3 | 2008-09-01 |
| Completed | Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste Hypersensitivity | Phase 3 | 2008-07-01 |
| Completed | Clinical Study to Evaluate Dental Plaque Gingival Diseases | Phase 3 | 2008-05-01 |
| Completed | Investigate Oral Bacteria in Adult Population Oral Bacteria | Phase 3 | 2008-05-01 |
| Completed | Development of Clinical Method to Triclosan Retention in Plaque Following Brushing Dental Plaque | Phase 3 | 2008-05-01 |
| Completed | Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction Hypersensitivity | N/A | 2008-05-01 |
| Completed | Effect on Bacterial Glycolytic Acid Formation on Plaque Dental Plaque | Phase 3 | 2008-04-01 |
| Completed | Train New Examiners Via Modified Gingival Margin Plaque Dental Plaque | Phase 3 | 2008-03-01 |
| Completed | Compare the Clinical Efficacy of Prototype Toothpastes. Gingival Diseases | Phase 3 | 2008-03-01 |
| Completed | Collection of Gingival Crevicular Fluid From Periodontitis Patients Gingival Diseases | Phase 3 | 2008-03-01 |
| Completed | Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse Dental Plaque | Phase 3 | 2008-03-01 |
| Completed | Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes Dental Plaque | Phase 3 | 2008-02-01 |
| Completed | Investigation of Dental Plaque and Gingival Index Dental Plaque | Phase 3 | 2008-02-01 |
| Completed | Evaluate Clinical Research From Commerical Oral Care Products Gingival Diseases | Phase 3 | 2008-01-01 |
| Completed | Compare the Clinical Efficacy of Prototype Toothpastes Dental Plaque | Phase 3 | 2008-01-01 |
| Completed | Training and Calibration of Dental Examiners Dental Plaque | Phase 3 | 2007-11-01 |
| Completed | Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing. Gingival Diseases | Phase 3 | 2007-10-01 |
| Completed | Clinical Research Study Efficacy of a Prototype Oral Rinse Dental Plaque | Phase 3 | 2007-10-01 |
| Completed | Efficacy of Salivary Bacteria and Post Brushing Salivary Bacteria Levels | Phase 3 | 2007-10-01 |
| Completed | Clinical Study to Compare Dental Plaque Control Dental Plaque | Phase 3 | 2007-09-01 |
| Completed | Evaluating Commercial Anti-Plaque Products and Oral Rinse Dental Plaque | Phase 2 | 2007-08-01 |
| Completed | To Access the Effects of Mucositis in Adults With Dental Implants Mucositis | Phase 3 | 2007-06-01 |
| Completed | Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis Gingivitis | Phase 3 | 2007-06-01 |
| Completed | Clinical Study to Examine Brushing on Dental Implants Gingival Diseases | Phase 3 | 2007-04-01 |
| Completed | Evaluate Inflammation Caused by Gingivitis in Adults Gingivitis | Phase 4 | 2007-01-01 |
| Completed | The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics Periodontal Disease | Phase 3 | 2006-05-01 |
| Completed | Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Popu Periodontitis | Phase 3 | 2006-03-01 |
| Unknown | Periodontal Disease and Cardiovascular Disease Periodontal Diseases | Phase 3 | 2000-11-01 |