NCT07414173

6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health

Clinical Investigation to Assess the Efficacy of an Antimicrobial Mouthrinse in the Reduction of Established Plaque and the Improvement of Gum Health: a 6-month Clinical Study

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health. Participants will: * Brush and rinse twice a day with the designated products for 6 months * Visit the clinic once every 3 months after baseline for reassessment.

Conditions

• Gingivitis
• Dental Plaque Accumulation

Interventions

Type	Name	Description
OTHER	Test Mouthrinse	Test Mouthrinse: 0.0553% NaF (250 ppm Fluoride), Amine and 0.2% Zinc Lactate dihydrate
OTHER	Control Mouthrinse	Control Mouthrinse: 0.0553% NaF(250 ppm Fluoride)

Timeline

• Start date: 2026-01-28
• Primary completion: 2026-09-01
• Completion: 2026-11-01
• First posted: 2026-02-17
• Last updated: 2026-02-17

Locations

1 site across 1 country: Germany