NCT04033575

Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste

Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste in Reducing Plaque and Gingivitis - a Three Month Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to evaluate the clinical efficacy of a toothpaste containing stannous fluoride as compared to Colgate Fluoride Toothpaste in reducing plaque and gingivitis - a three- month study.

Detailed description

This was a 6-month, randomized, single-center, parallel group, double-blinded, clinical research study to assess the clinical efficacy of two toothpastes containing stannous fluoride (SnHW and CPH) as compared to Regular Fluoride Toothpaste on the reduction of established dental plaque and gingivitis in adults.

Conditions

• Gingivitis

Interventions

Type	Name	Description
DRUG	Colgate Total SF	1100 ppm F Colgate Total Clean Mint White Paste Toothpaste is a test treatment
DRUG	Colgate Cavity Protection toothpaste	0.76% monofluorophosphate (1000 ppm MFP), Colgate Cavity Protection toothpaste is a control treatment.

Timeline

• Start date: 2019-03-06
• Primary completion: 2019-06-06
• Completion: 2019-07-01
• First posted: 2019-07-26
• Last updated: 2022-09-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study