NCT06353165

Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva

A Clinical Study to Investigate Stannous Fluoride Toothpaste on Antibacterial Effects in the Different Regions of the Mouth as Compared to Colgate Cavity Protection Toothpaste

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed as Colgate Cavity Protection Toothpaste) in different regions of the mouth (dental plaque, tongue, cheek, gum surface and in saliva) 12 hours post-brushing (overnight) after 2 and 4 weeks of product use.

Conditions

• Plaque, Dental

Interventions

Type	Name	Description
DRUG	Stannous fluoride toothpaste	product containing 0.45% stannous fluoride
DRUG	Colgate Dental Cream	product containing 0.76% sodium monofluorophosphate

Timeline

• Start date: 2023-03-08
• Primary completion: 2023-04-12
• Completion: 2023-04-12
• First posted: 2024-04-08
• Last updated: 2024-04-15

Locations

1 site across 1 country: Thailand