NCT06955871

Clinical Investigation of Bleeding Reduction Efficacy on Toothpaste Containing 1.05% Chitosan

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the bleeding reduction efficacy of toothpaste containing 1.05% Chitosan compared to a regular fluoride toothpaste, and compared to a toothpaste containing 67% bicarbonate.

Conditions

• Bleeding Gum
• Gingivitis

Interventions

Type	Name	Description
OTHER	Toothpaste containing 1.05% Chitosan	Toothpaste containing 1.05% Chitosan
OTHER	Silica-based NaF Toothpaste	Silica-based NaF Toothpaste
OTHER	Toothpaste with 67% bicarbonate	Toothpaste containing 67% Bicarbonate

Timeline

• Start date: 2025-04-29
• Primary completion: 2025-06-04
• Completion: 2025-06-04
• First posted: 2025-05-02
• Last updated: 2025-08-15

Locations

1 site across 1 country: China