NCT06956599

Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste

Clinical Investigation of Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Assess the clinical efficacy of 5% Potassium Nitrate Toothpaste (Colgate-Palmolive Company, New York, NY, USA) on providing dentinal hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection Toothpaste (Colgate-Palmolive Company, New York, NY, USA) over an eight-week period

Conditions

• Dentin Hypersensitivity

Interventions

Type	Name	Description
DRUG	test toothpaste	A commercially available fluoride toothpaste
DRUG	Control toothpaste	A commercially available fluoride toothpaste

Timeline

• Start date: 2025-05-10
• Primary completion: 2025-08-11
• Completion: 2025-08-11
• First posted: 2025-05-04
• Last updated: 2026-03-19

Locations

1 site across 1 country: China