| Not Yet Recruiting | Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity NCT07449169 | Cairo University | N/A |
| Not Yet Recruiting | Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated. NCT07195357 | Indiana University | — |
| Recruiting | A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Su NCT07337109 | HALEON | — |
| Completed | A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Tooth NCT07297732 | HALEON | N/A |
| Not Yet Recruiting | Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations NCT07188142 | Beenish Hassan | Phase 2 / Phase 3 |
| Active Not Recruiting | Laser Therapy for Dentin Hypersensitivity NCT07431736 | Hacettepe University | N/A |
| Recruiting | Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice NCT07215767 | HALEON | Phase 3 |
| Not Yet Recruiting | Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivi NCT07120139 | Rawda Hesham Abd ElAziz | N/A |
| Recruiting | Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac Patients NCT07069127 | University of Pavia | N/A |
| Completed | Combined Use of Potassium Nitrate Gel and Diode Laser for Dentin Hypersensitivity NCT06967818 | University of Pavia | N/A |
| Completed | Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Too NCT06956599 | Colgate Palmolive | Phase 3 |
| Not Yet Recruiting | Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hy NCT06854068 | Ege University | N/A |
| Not Yet Recruiting | Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivi NCT06557980 | Minia University | N/A |
| Completed | Management of Dentin Hypersensitivity in Patients With Periodontitis NCT07068724 | Trakya University | N/A |
| Active Not Recruiting | Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hyp NCT07113847 | British University In Egypt | Phase 2 / Phase 3 |
| Recruiting | Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hyper NCT06627790 | Dr. D. Y. Patil Dental College & Hospital | Phase 3 |
| Completed | Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Cari NCT07063433 | British University In Egypt | N/A |
| Completed | Clinical Efficacy of Using Bioactive Desensitizer Gel NCT07323693 | Cairo University | N/A |
| Completed | Evaluation of Biomimetic Mineralization Plus Soft Laser Irradiation in Dentin Hypersensitivity Management NCT06829277 | MTI University | N/A |
| Completed | Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity NCT06464939 | HysensBio Co., Ltd | Phase 2 |
| Not Yet Recruiting | Dentin Hypersensitivity - Varnish or Laser? NCT06539286 | Sigmund Freud PrivatUniversitat | N/A |
| Completed | Effect of an Experimental Gel Based on Acmella Oleracea Extract Associated or Not With Fluoride on Dentin Hype NCT06971783 | Universidade Federal do Para | N/A |
| Completed | Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies NCT07511530 | Prof. Mayyas Al-Remawi | N/A |
| Not Yet Recruiting | Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of NCT06493500 | Cairo University | Phase 1 |
| Enrolling By Invitation | Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents NCT06837779 | Al-Azhar University | N/A |
| Completed | Validation of a French Version of the DHEQ NCT06466200 | University Hospital, Clermont-Ferrand | N/A |
| Unknown | The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Ra NCT06276777 | Eman Omar Elfarouk | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of KH001 in Patients with Dentin Hypersensitivity NCT06264453 | HysensBio Co., Ltd | Phase 2 |
| Unknown | Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivit NCT06154941 | Cairo University | N/A |
| Unknown | Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity NCT05927831 | Manipal University College Malaysia | N/A |
| Completed | A Comparison Study of Hypersensitivity Treatment NCT05768373 | Solventum US LLC | N/A |
| Completed | Efficacy of Universal Bonding Agents as Desensitizers NCT07197437 | Peking University Hospital of Stomatology | N/A |
| Completed | The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles NCT06025084 | Egymedicalpedia | Phase 1 |
| Completed | Toothpastes With Thermal Water for Oral Health NCT05623761 | I.M. Sechenov First Moscow State Medical University | Phase 4 |
| Completed | Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration, Dentin Bonding, and Clinical Durabili NCT05501691 | Alexandria University | N/A |
| Completed | The Influence of Desensitizing Agent on Postoperative Sensitivity in Posterior Composite Restoration NCT06113874 | Nourhan M.Aly | N/A |
| Unknown | Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride NCT04731766 | Nayera Hassanien Mohamed | N/A |
| Completed | Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite for Dentin Hypersensitivity Management NCT04896294 | I.M. Sechenov First Moscow State Medical University | Phase 4 |
| Unknown | Desensitizing Efficacy of Polymeric Nano Calcium Fluoride Containing Varnish NCT04614727 | Samar Saad | N/A |
| Unknown | Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity NCT04484844 | Cairo University | Phase 2 / Phase 3 |
| Completed | Comparative Study on the Efficacy of OliNano SEAL and Curodont D' Senz in Treatment of Dentin Hypersensitivity NCT05122312 | Al-Azhar University | Phase 4 |
| Completed | The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life NCT04887181 | Kırıkkale University | N/A |
| Completed | Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth NCT04804423 | University Medicine Greifswald | Phase 2 / Phase 3 |
| Completed | Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis NCT04512625 | University of Jazan | N/A |
| Completed | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH NCT04249336 | Dow University of Health Sciences | Phase 3 |
| Completed | Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal P NCT04422184 | University of Sao Paulo | Phase 4 |
| Completed | A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity NCT03965039 | Procter and Gamble | N/A |
| Completed | Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity NCT03943095 | GlaxoSmithKline | Phase 2 |
| Completed | A Comparison of Long-Term Effectiveness of Two Desensitizing Products NCT03851900 | Baskent University | N/A |
| Completed | Comparison of Desensitizing Materials NCT04527159 | Nourah Mulfi Aljasser | N/A |
| Completed | Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity NCT04819867 | Dow University of Health Sciences | Phase 2 / Phase 3 |
| Completed | Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity NCT04225247 | Dow University of Health Sciences | Phase 3 |
| Unknown | 8% L-Arginine/Calcium Carbonate Toothpaste in Comparison to Strontium Acetate Toothpaste for Hypersensitive De NCT03068533 | Cairo University | N/A |
| Unknown | Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity NCT03076944 | Federal University of Uberlandia | N/A |
| Unknown | Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment NCT03083496 | Federal University of Uberlandia | N/A |
| Unknown | Reduction of Dentine Hypersensitivity Using 8% Arginine Based Toothpaste and 8% Strontium Acetate Based Toothp NCT03061383 | Cairo University | N/A |
| Completed | Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity NCT04591444 | University of Sao Paulo | Phase 3 |
| Completed | Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity NCT02936830 | Riyadh Colleges of Dentistry and Pharmacy | Phase 4 |
| Completed | Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment NCT02931734 | Federal University of Uberlandia | N/A |
| Completed | Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity NCT02483013 | University of Sao Paulo | Phase 4 |
| Completed | Evaluation of Dentin Hypersensitivity Using Glass Ionomer Cements NCT02378129 | Federal University of Pelotas | Phase 2 / Phase 3 |
| Completed | Silver and Fluoride Salivary Levels After the Application of Silver Fluoride NCT01860391 | Universidad Peruana Cayetano Heredia | N/A |
| Completed | The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching NCT02316080 | University of Sao Paulo | Phase 4 |
| Completed | The Efficacy of a Toothpaste to Reduce Sensitivity NCT00763269 | Colgate Palmolive | Phase 3 |
| Completed | Cyanoacrylate and Laser and Dentin Sensitivity NCT01111474 | Federal University of São Paulo | N/A |
| Completed | Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment NCT00926484 | Huazhong University of Science and Technology | — |