NCT03851900

A Comparison of Long-Term Effectiveness of Two Desensitizing Products

A Comparison of Long-Term Effectiveness of Two Desensitizing Products: A Randomized Clinical Placebo-Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Baskent University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water). At least 150 teeth wil be treated with desensitizing products and placebo randomly one third usig TM, one third using SE and one third using placebo. The efficiency of the materials will be evaluated at baseline, 1 week, 1 month, 3 months and 6 months after treatment.

Detailed description

The aim of this randomized, controlled, clinical trial is to compare the clinical efficacy of a desensitizer that contains calcium phosphate with a two-step self-etch adhesive and placebo through a long-term period (6 months). At least fifty patients with a sensitivity score of 6 or higher, according to the Visual Analog Scale (VAS), with at least three teeth will participate in this study. Teethmate Desensitizer (TM), Clearfil SE Bond 2 (SE) and placebo (distilled water) will be applied randomly to three teeth of each patient. Recalls will be done at baseline, 1 week, 1 month, 3 months and 6 months after treatment by applying air-blast and the sensitivity scores will be determined according to VAS. The efficiency of the materials will be determined according to the VAS scores. Data will be analyzed using Paired t test and repeated measures of ANOVA.

Conditions

• Dentin Hypersensitivity

Interventions

Type	Name	Description
OTHER	Teethmate Desensitizer (TM)	Desensitizing agent will be applied to sensitive teeth.
OTHER	Clearfil SE Bond 2	Desensitizing agent will be applied to sensitive teeth.
OTHER	Distilled water	Placebo will be applied to sensitive teeth as a negative control.

Timeline

• Start date: 2019-02-01
• Primary completion: 2019-10-01
• Completion: 2019-10-01
• First posted: 2019-02-22
• Last updated: 2019-10-03

Locations

1 site across 1 country: Turkey (Türkiye)