NCT06837779

Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents

Clinical Evaluation of Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis Application in Comparison With Two Different Remineralizing Agents (a Randomized Clinical Trial)

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 35 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity. It will also learn about the safety of using fluoride iontophoresis with Acidulated phosphate fluoride gel. The main questions it aims to answer are: Does the remineralizing agent have the ability to decrease dentin sensitivity? Researchers will compare Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel , Casein phosphopeptides-Amorphus calcium phosphate (CPP-ACP), nano-hydroxyapptite (NHAP) and -active glass in decreasing dentin hypersensitivity . Participants will: * Application of remineralizing agent every 3 months * Visit the dental clinic once every 3 months for checkups and tests

Detailed description

Assess the efficacy of fluoride iontophoresis in remineralization in comparison with other ingredients.

Conditions

• Dentin Hypersensitivity

Interventions

Type	Name	Description
DRUG	Fluoride Iontophoresis with Acidulated Phosphate Fluoride	Application of fluoride gel and activated with Iontophoresis electrical pole
DRUG	Remineralization with sodium fluoride varnish	CASIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE

Timeline

• Start date: 2024-07-01
• Primary completion: 2025-08-01
• Completion: 2025-12-01
• First posted: 2025-02-20
• Last updated: 2025-02-20

Locations

1 site across 1 country: Egypt