NCT07197437

Efficacy of Universal Bonding Agents as Desensitizers

Clinical Efficacy of Resin Based Coating Materials for Protecting Dental Root

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Peking University Hospital of Stomatology · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if the adhesive Single Bond Universal works to treat dentin hypersensitivity in adults. It will also learn about the durability of Single Bond Universal. The main questions it aims to answer are: Does Single Bond Universal has the function to treat dentin hypersensitivity in adults? Researchers will compare Single Bond Universal to a traditional desensitizer Hybrid Coat to see which one has higher efficiency and longer durability. Participants will: Receive the treatment of Single Bond Universal or Hybrid Coat at the first visit. Visit the clinic at 1, 3, 6, 9, 12 months for follow-up evaluation. Reassess dentin sensitivity at each visit and record in terms of VAS score.

Detailed description

This is a randomized, double-blind and controlled study to include 14 patients with dentin sensitivity. The study is a randomized controlled trial with split mouth control, with symmetrical tooth positions on both sides of the same patient as test and control groups, the test group being the group using the universal bonding agent and the control group being the group using the clinically used desensitizer (Hybrid Coat). Improvement in dentin sensitivity symptoms was the primary outcome indicator observed. Dentin sensitivity was assessed by evaluating the reduction in dentin sensitivity VAS scores at immediately, 1 month, 3 months, 6 months, 9 months and 12 months points after the desensitization treatment. Safety was assessed by evaluating appliance defects and adverse events at the same time points after the desensitization treatment.

Conditions

• Dentin Hypersensitivity

Interventions

Type	Name	Description
DEVICE	Hybrid Coat desensitizer	Dental desensitization treatment
DEVICE	Single Bond Universal as desensitizer	Dental desensitization treatment

Timeline

• Start date: 2023-02-27
• Primary completion: 2025-03-07
• Completion: 2025-03-07
• First posted: 2025-09-29
• Last updated: 2025-09-29

Locations

1 site across 1 country: China