NCT04731766

Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride

Effectiveness of Using Nano-Silver Fluoride Varnish Versus Sodium Fluoride Varnish in Management of Cervical Dentin Hypersensitivity in Adult Patients: A Randomized Clinical Trial.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (estimated)
• Sponsor: Nayera Hassanien Mohamed · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.

Detailed description

In-vivo part: Each varnish will be applied separately on different teeth according to the manufacturer's instructions and the VAS will be measured according to a specific timeline: T0 (baseline, before application of varnish), T1 (1 week after application), T2 (4 weeks after application) and T3 (4 weeks after application). In-situ part: Dentin specimen will be prepared from extracted teeth from the orthodontic department in our college, sterilized and prepared. it will be bonded to an orthodontic wire and bonded to upper first molar. Dentinal occlusion will be measured using scanning electron microscope following the same timeline.

Conditions

• Dentin Hypersensitivity

Interventions

Type	Name	Description
BEHAVIORAL	Citrine 5 % sodium fluoride	Citrine varnish is a 5% sodium fluoride varnish, It was developed to prolong the contact between the tooth surface and fluoride to increase the resistance against caries attack and manage tooth hypersensitivity; the active ingredient of fluoride varnish is mostly 5% sodium fluoride.
BEHAVIORAL	concocted nano-silver fluoride	Nano-silver fluoride (NSF) is a solution which has been introduced as an experimental formulation in which it's stability for three years has been proved by Santos et al. The laboratory synthesis of concocted NSF was carried out in a nano-technology center; Several trials were done until we have reached a successful end product.

Timeline

• Start date: 2021-11-01
• Primary completion: 2022-01-01
• Completion: 2022-01-01
• First posted: 2021-02-01
• Last updated: 2021-02-01