NCT07442136

Clinical Study to Assess the Efficacy of New Toothpaste Containing SnF as Compared to Colgate Cavity Protection Toothpaste on the Reduction of Enamel Erosion

• Status: Active Not Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if a new toothpaste can prevent enamel erosion in healthy adults. Researchers will compare the test toothpaste to a control toothpaste to see if there is a difference in erosion levels. Participants will brush twice a day for two minutes with their assigned toothpaste.

Detailed description

The objective of this clinical study is to assess the efficacy of New Toothpaste Containing SnF as compared to commercially available toothpaste in the reduction of enamel erosion over a ten (10) days period. This investigation will be a randomized, double-blinded, single-center, parallel clinical study. Subjects will be randomly assigned to one of the two study groups, and will be instructed to use their assigned toothpaste for a period of ten (10) days.

Conditions

• Enamel Erosion

Interventions

Type	Name	Description
DRUG	New Toothpaste Containing SnF	Participants will brush with a new toothpaste containing SnF for two minutes twice daily.
DRUG	Fluoride Toothpaste	Participants will brush with a regular fluoride toothpaste twice daily for two minutes.

Timeline

• Start date: 2026-03-03
• Primary completion: 2026-04-01
• Completion: 2026-04-01
• First posted: 2026-03-02
• Last updated: 2026-03-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study