NCT06300866

Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste

The Clinical Investigation of Stannous Fluoride Containing Toothpaste Compared to Colgate Cavity Protection Toothpaste in Reducing Plaque and Gingivitis - a Six-month Study in California

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of product use.

Conditions

• Gingivitis
• Plaque, Dental

Interventions

Type	Name	Description
DRUG	Test	test toothpaste containing 0.45% stannous fluoride
DRUG	Control	toothpaste containing 0.76% sodium monofluorophosphate

Timeline

• Start date: 2020-08-18
• Primary completion: 2021-03-08
• Completion: 2021-03-08
• First posted: 2024-03-08
• Last updated: 2024-03-08

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study