NCT06770114

Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use

A Clinical Study to Investigate a New Mouthwash Containing 0.075% CPC, and 0.1% Hyaluronic Acid and 0.28% Zinc Lactate as Compared to a Fluoride Mouthwash Containing 0.044% NaF in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.

Conditions

• Gingivitis

Interventions

Type	Name	Description
DRUG	Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash	0 .075 % cetylpyridinium chloride and 0 .28 % zinc lactate
DRUG	PhosFlur Mouthwash	0 .044 % sodium fluoride

Timeline

• Start date: 2021-10-18
• Primary completion: 2022-05-09
• Completion: 2022-05-09
• First posted: 2025-01-13
• Last updated: 2025-12-01

Locations

1 site across 1 country: Italy

Regulatory

• FDA-regulated drug study