NCT07398846

Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

A 12-Week Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 135 (estimated)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To evaluate the efficacy of a stannous fluoride toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

Conditions

• Plaque

Interventions

Type	Name	Description
DRUG	0.454%Stannous fluoride toothpaste	toothpaste
DRUG	0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe	mouthwash
DRUG	0.76% Sodium Monofluorophosphate (Na MFP) toothpaste	toothpaste
DRUG	0.022% Sodium Fluoride mouthwash	mouthwash

Timeline

• Start date: 2026-01-26
• Primary completion: 2026-04-20
• Completion: 2026-04-20
• First posted: 2026-02-10
• Last updated: 2026-02-10

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study