| Not Yet Recruiting | A Study to Investigate Stannous Fluoride Containing Toothpaste on Antibacterial Effects in the Different Regio NCT07458464 | Colgate Palmolive | Phase 3 |
| Recruiting | Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and O NCT07501455 | Kenvue Brands LLC | N/A |
| Recruiting | Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen NCT07398846 | Colgate Palmolive | Phase 3 |
| Completed | The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis NCT07224828 | Colgate Palmolive | Phase 3 |
| Recruiting | Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - NCT06939374 | Cryotherapeutics SA | N/A |
| Completed | Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush NCT06561204 | University of Minnesota | N/A |
| Active Not Recruiting | Recycling of Three Pressable Ceramics With Different Weight Percentage NCT06575803 | Faculty of Dental Medicine for Girls | N/A |
| Completed | Effect of Probiotic Toothpaste and Regular Toothpaste on Plaque Levels of Orthodontic Patients NCT06473792 | Kanza Tahir | N/A |
| Completed | The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protec NCT06427499 | Colgate Palmolive | Phase 3 |
| Completed | Efficacy and Safety Evaluation of Jet Floss EX After 8-week Application NCT06718959 | Guang Dong Bixdo Health Technology Co.,Ltd | N/A |
| Completed | Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental NCT06244303 | Colgate Palmolive | Phase 3 |
| Completed | Efficacy of Regular, Musical and Electric Toothbrushes in Plaque Removal in Children NCT06541743 | Jouf University | N/A |
| Completed | Multi-Media Parent-based Intervention to Promote Dental Hygiene Among Young Children: BeReady2Smile II NCT05321719 | Oregon Research Behavioral Intervention Strategies, Inc. | N/A |
| Withdrawn | Regular Antibacterial Photodynamic Therapy on Oral Hygiene in the Elderly 24-hour Care NCT05720104 | Koite Health Oy | N/A |
| Unknown | Evaluating the Performance and Safety of the Medical Device Plenhyage® in the Treatment of Dermal Tissue Defec NCT05239117 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Unknown | Evaluating the Performance and Safety of the Medical Device Auralya® in the Treatment of Facial Dermal Tissue NCT05239130 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Evaluating the Performance and Safety of the Medical Device Janesse in the Treatment of Facial Dermal Tissue D NCT05239156 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue NCT05239351 | I.R.A. Istituto Ricerche Applicate S.p.A. | N/A |
| Completed | Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste. NCT06563518 | Colgate Palmolive | Phase 2 |
| Completed | A Study of Experimental Mouthwashes NCT05121909 | Johnson & Johnson Consumer Inc. (J&JCI) | Phase 4 |
| Not Yet Recruiting | COMORAL® the Oral Irrigation Unit Clinical Trial NCT05031260 | University of California, Los Angeles | N/A |
| Completed | The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy Patients NCT05091216 | Lo-Sheng Sanatorium | N/A |
| Completed | Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use NCT04899440 | Procter and Gamble | — |
| Completed | A Twelve Week Study of Experimental Mouth Rinses NCT05120141 | Johnson & Johnson Consumer Inc. (J&JCI) | Phase 4 |
| Completed | A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems NCT05821712 | Colgate Palmolive | Phase 3 |
| Completed | Efficacy of the Disclosing Plaque Agent as a Guide to Remove the Oral Biofilm in Orthodontic Patients. NCT05428189 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | N/A |
| Completed | ToothWave Calculus Reduction and Accumulation Prevention Study NCT04596761 | Home Skinovations Ltd. | N/A |
| Completed | Convalescent Plasma Therapy in Patients With COVID-19 NCT04407208 | Biofarma | Phase 1 |
| Unknown | Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health NCT04197427 | You First Services | N/A |
| Completed | Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults NCT06318819 | Maha A. Bahammam | N/A |
| Completed | Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque NCT04921371 | Johnson & Johnson Consumer Inc. (J&JCI) | Phase 1 |
| Unknown | Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients NCT03877705 | Cairo University | EARLY_Phase 1 |
| Completed | Safety and Efficacy of the ToothWave -12 Weeks Calculus Study NCT04092075 | Home Skinovations Ltd. | N/A |
| Completed | Self-selection Study of the Toothwave Toothbrush NCT04023097 | Home Skinovations Ltd. | N/A |
| Completed | The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation NCT03989427 | Melaka Manipal Medical College | N/A |
| Completed | ToothWave Plaque and Gingivitis Study NCT03885323 | Home Skinovations Ltd. | N/A |
| Completed | The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health NCT04017507 | Procter and Gamble | — |
| Completed | A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis NCT03421145 | Solventum US LLC | — |
| Completed | Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples NCT05138978 | Colgate Palmolive | Phase 2 |
| Completed | Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Chi NCT04057430 | University of California, Los Angeles | N/A |
| Unknown | Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control NCT03099551 | Faculty Sao Leopoldo Mandic Campinas | Phase 4 |
| Completed | Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mout NCT03550651 | Government College of Dentistry, Indore | N/A |
| Completed | Dental Plaque Microbiota in Caries-free and Caries-active Children NCT03906981 | Kuwait University | — |
| Completed | Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex NCT02634931 | Nobelpharma | Phase 3 |
| Completed | Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Comple NCT02635789 | Nobelpharma | Phase 3 |
| Completed | Trial of Toothpaste to Reduce Plaque and Inflammation NCT02666508 | University of Illinois at Chicago | N/A |
| Completed | A Pilot Study to Evaluate a Molecular Method for Plaque NCT02574221 | Procter and Gamble | N/A |
| Completed | A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifr NCT02543060 | Procter and Gamble | N/A |
| Completed | Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis NCT02718014 | Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre | Phase 1 / Phase 2 |
| Unknown | Adverse Plaque Characteristics in CCTA and TVC Imaging NCT02350959 | National Health Insurance Service Ilsan Hospital | Phase 4 |
| Unknown | DD2-Coronary Plaque Morphology and Plaque Progression NCT03022344 | Esbjerg Hospital - University Hospital of Southern Denmark | N/A |
| Completed | A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation NCT02233998 | Johnson & Johnson Consumer and Personal Products Worldwide | N/A |
| Completed | Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population NCT01877421 | U.S. Army Medical Research and Development Command | Phase 1 / Phase 2 |
| Completed | Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study NCT02980497 | Johnson & Johnson Consumer and Personal Products Worldwide | N/A |
| Completed | Pd/Pa vs iFR™ in an Unselected Population Referred for Invasive Angiography NCT02377310 | Golden Jubilee National Hospital | — |
| Unknown | Efficacy of a Mouthwash Containing Propolis NCT01750801 | Federal University of Minas Gerais | Phase 3 |
| Completed | A Study to Assess the Severity of Psoriasis in Brazilians Participants With Chronic Plaque-type Psoriasis NCT02274363 | Janssen Pharmaceutica | — |
| Completed | Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis NCT03214406 | Church & Dwight Company, Inc. | N/A |
| Completed | BioImage Study: A Clinical Study of Burden of Atherosclerotic Disease in an At-Risk Population NCT00738725 | BG Medicine, Inc | — |