NCT07224828

The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis

Clinical Investigation to Assess the Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis: a 12-week Clinical Study.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 130 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

A clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults.

Detailed description

This is a Phase III, randomized, single-center, parallel group, double blind, clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults. This study will have 3 arms to determine the efficacy of a battery toothbrush vs a positive control regimen and a negative control regimen to reduce plaque and gingivitis.

Conditions

• Plaque
• Gingivitis

Interventions

Type	Name	Description
DRUG	Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush	0.454 Stannous Fluoride toothpaste with battery toothbrush
DRUG	Colgate Great Regular + Total Active Prevention Battery Toothbrush	regular fluoride toothpaste with battery toothbrush
DRUG	Colgate Great Regular + standard reference flat trim toothpaste	regular fluoride toothpaste with manual toothbrush

Timeline

• Start date: 2025-10-14
• Primary completion: 2026-01-28
• Completion: 2026-01-28
• First posted: 2025-11-05
• Last updated: 2026-02-06

Locations

1 site across 1 country: Puerto Rico

Regulatory

• FDA-regulated drug study