NCT06957249

Clinical Study to Evaluate the Tooth Whitening Efficacy

Clinical Study to Evaluate the Tooth Whitening Efficacy of a Colgate Toothpaste With 5% Hydrogen Peroxide and Fluoride Compared to a Toothpaste With 0% Hydrogen Peroxide and Fluoride Over a One-Week Period.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Optic White 5%HP ActivShine TP vs Crest3D White TP (head-to-head whitening clinical) The objective of this study is to evaluate the tooth whitening efficacy of a Colgate toothpaste with 5% Hydrogen Peroxide and Fluoride compared to a toothpaste with 0% Hydrogen Peroxide and Fluoride over a one-week period.

Conditions

• Whitening

Interventions

Type	Name	Description
DRUG	Optic White 5%HP ActivShine Toothpaste	0.76% MFP toothpaste
DRUG	Crest3DWhite Advanced Radiant Mint Toothpaste	0.243% NaF toothpaste

Timeline

• Start date: 2025-04-25
• Primary completion: 2025-05-03
• Completion: 2025-05-05
• First posted: 2025-05-04
• Last updated: 2025-09-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study