NCT07210138

Clinical Investigation of PerioGard (Test) Regimen

The Clinical Investigation of PerioGard (Test) Regimen Compared to Control Regimen in Reducing Plaque and Gingivitis - a Three-month Study in Thailand

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The objective of this three-month clinical research study is to evaluate the clinical efficacy of the PerioGard (test) regimen (0.45% SnF-HW Toothpaste, CPC-Zinc-Fluoride Mouthwash, Gummy Toothbrush) compared to the control regimen (regular fluoride toothpaste, fluoride mouthwash, flat-trim toothbrush) in reducing gingivitis and dental plaque in adults

Conditions

• Gingivitis

Interventions

Type	Name	Description
DRUG	PeriGuard regimen	0.45% Stannous Fluoride Toothpaste, CPC-Zinc Fluoride Mouthwash, Gummy Toothbrush
DRUG	Colgate Dental Cream regimen	Colgate Cavity Protection Toothpaste, Fluoride Mouthwash,Colgate Extra Clean Soft-Bristled Toothbrush

Timeline

• Start date: 2025-08-18
• Primary completion: 2025-12-30
• Completion: 2025-12-30
• First posted: 2025-10-07
• Last updated: 2026-03-18

Locations

1 site across 1 country: Thailand

Regulatory

• FDA-regulated drug study