NCT06565897

Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.

Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Established Plaque and Gingivitis: a 6-week Clinical Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Colgate Palmolive · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after 1, 3, and 6, weeks of unsupervised product use at home. All subjects will be followed for adverse events throughout the study

Conditions

• Plaque, Dental
• Gingivitis

Interventions

Type	Name	Description
DRUG	Test regimen	toothpaste \& manual toothbrush
DRUG	Control regimen	toothpaste \& manual toothbrush

Timeline

• Start date: 2024-07-26
• Primary completion: 2024-09-10
• Completion: 2024-09-10
• First posted: 2024-08-22
• Last updated: 2026-03-18

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study