| Not Yet Recruiting | A Study of the Effect of a Nurse Navigator Program on High Risk Patients NCT05592847 | Mayo Clinic | N/A |
| Recruiting | SMART-r: Substance Monitoring and Active Relapse Tracking Repository NCT06676059 | National Institute on Drug Abuse (NIDA) | — |
| Withdrawn | fNIRs-based Neurofeedback to Reduce Relapse in pOUD/AUD NCT03595293 | Milton S. Hershey Medical Center | N/A |
| Recruiting | Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controll NCT06493773 | Zealand University Hospital | N/A |
| Recruiting | Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of A NCT07216872 | Brainsway | N/A |
| Recruiting | Cohort Study on Medical Students' Mental Health NCT07305701 | Centre Hospitalier Régional d'Orléans | — |
| Recruiting | Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder NCT06415721 | VA Palo Alto Health Care System | N/A |
| Recruiting | Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design NCT07125534 | University of Illinois at Urbana-Champaign | N/A |
| Recruiting | A Trial to Investigate the Effects of Cannabidiol Plus Naltrexone on Alcohol Craving in Patients With Alcohol NCT06845124 | Central Institute of Mental Health, Mannheim | Phase 2 |
| Recruiting | Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in NCT06969937 | Dr. med. Marcus Herdener | Phase 2 |
| Recruiting | Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder NCT06939088 | Anders Fink-Jensen, MD, DMSci | Phase 2 |
| Completed | Drivers of Suicide Mobile App Study NCT05427734 | Evidence-Based Practice Institute, Seattle, WA | N/A |
| Recruiting | Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction NCT06916754 | Beykoz University | N/A |
| Not Yet Recruiting | Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use NCT06256952 | Charite University, Berlin, Germany | N/A |
| Recruiting | Role of Pavlovian Mechanisms for Control Over Substance Use NCT06701487 | Technische Universität Dresden | — |
| Recruiting | Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study NCT06687525 | University of Illinois at Urbana-Champaign | — |
| Recruiting | Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder NCT05995769 | University of Calgary | Phase 2 |
| Recruiting | Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder NCT06701500 | Technische Universität Dresden | — |
| Active Not Recruiting | Telehealth Treatment for Alcohol Use Disorder NCT05747703 | Ria Health | N/A |
| Completed | EMPOWER AUD Pivotal Trial NCT05948605 | Theranova, L.L.C. | N/A |
| Completed | Effect of Baclofen to Prevent Post-Traumatic Stress Disorder NCT05877807 | Nantes University Hospital | — |
| Recruiting | The Liver Care Trial NCT05855031 | Zealand University Hospital | N/A |
| Withdrawn | Study of the Neural Substrates of Alcohol Craving by High-resolution Electroencephalography NCT05275166 | Rennes University Hospital | N/A |
| Active Not Recruiting | Ibudilast for Treating Alcohol Use Disorder NCT05414240 | University of Pennsylvania | Phase 2 |
| Active Not Recruiting | Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support NCT05473598 | VA Office of Research and Development | N/A |
| Completed | Ibogaine in the Treatment of Alcoholism: an Open-label Escalating-dose Trial NCT03380728 | University of Sao Paulo | Phase 2 |
| Recruiting | CRP and S&A for Inpatient Veterans NCT05054738 | VA Office of Research and Development | N/A |
| Withdrawn | Digital Human-Based Brief Interventions for Harmful Alcohol Use: The PAHOLA Project NCT05906979 | Centre for Addiction and Mental Health | N/A |
| Recruiting | The Man Van Project NCT06357416 | Royal Marsden NHS Foundation Trust | N/A |
| Recruiting | Naltrexone in AUD Reward Drinkers NCT05028062 | University of Pennsylvania | Phase 4 |
| Completed | Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcoh NCT05093296 | Central Institute of Mental Health, Mannheim | Phase 2 / Phase 3 |
| Suspended | Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression NCT04934553 | Charles Taylor | N/A |
| Unknown | Pilot Study to Evaluate "Intégrer et Accompagner Les Consommations d'Alcool!" (IACA!)'s Impact and Transferabi NCT04927455 | University Hospital, Bordeaux | — |
| Recruiting | Effectiveness of High-frequency rTMS in Reducing Alcohol Consumption in Non-abstinent Patients With an Alcohol NCT04773691 | Centre Hospitalier Universitaire Dijon | N/A |
| Unknown | TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda NCT04743024 | University of Bergen | — |
| Unknown | PTSD, AUD, and Interpersonal Conflict: Within-person Associations NCT04552782 | University of South Dakota | N/A |
| Completed | Alcohol and Women : Screening in General NCT04647565 | University Hospital, Montpellier | — |
| Recruiting | Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer NCT05992272 | Charite University, Berlin, Germany | — |
| Completed | Investigation of the Efficacy of Acamprosate and Calcium in Comparison to Placebo as Validation of a Behaviour NCT03634917 | Technische Universität Dresden | Phase 3 |
| Completed | Neuroimmune Dysfunction in Alcohol Use Disorder NCT04210713 | University of Maryland, Baltimore | Phase 1 |
| Completed | Evaluation of Physical Activity of Patients Admitted to Addiction Service NCT04953403 | University Hospital, Montpellier | — |
| Completed | Impact of Integrating an Addiction Team on Post Liver Transplantation Survival for Alcohol-related Liver Disea NCT04964687 | University Hospital, Montpellier | — |
| Unknown | Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder NCT03969251 | Nassima Ait-Daoud Tiouririne | N/A |
| Completed | Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence NCT02120365 | Virginia Commonwealth University | Phase 1 / Phase 2 |
| Unknown | Messaging Interventions to Reduce Alcohol Problems Project NCT03695653 | Partnership to End Addiction | N/A |
| Completed | Varenicline and Bupropion for Alcohol Use Disorder NCT04167306 | Vastra Gotaland Region | Phase 2 |
| Unknown | Vortioxetine for Treatment of Depressive Mood and Alcohol Use NCT04498897 | Hanyang University Seoul Hospital | Phase 2 |
| Completed | Impact of Marketing of Alcohol Products on Young People NCT03818750 | Rennes University Hospital | N/A |
| Active Not Recruiting | Behavioral Alcohol Responses (BAR) Study NCT03467191 | Carnegie Mellon University | EARLY_Phase 1 |
| Terminated | A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study) NCT03060772 | Emory University | Phase 2 |
| Completed | Understanding Alcohol Reward in Social Context NCT03449095 | University of Illinois at Urbana-Champaign | N/A |
| Completed | Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study NCT03339024 | Norwegian University of Science and Technology | Phase 3 |
| Completed | Ketogenic Diet (KD) in Alcoholism NCT03255031 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | N/A |
| Completed | Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot NCT03152760 | National Institute on Drug Abuse (NIDA) | — |
| Recruiting | Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent NCT06262958 | Kuopio University Hospital | N/A |
| Unknown | Dietary Fiber Intake in Alcohol-dependent Patients NCT03803709 | Université Catholique de Louvain | N/A |
| Unknown | Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder NCT03120468 | Nassima Ait-Daoud Tiouririne | EARLY_Phase 1 |
| Completed | Testing Doxazosin to Treat Stress Mechanisms in Alcoholism NCT02989493 | University of Wisconsin, Madison | Phase 2 |
| Completed | Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mo NCT02668250 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home NCT02885311 | Northwell Health | Phase 1 / Phase 2 |
| Completed | Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking NCT02861807 | University of New Mexico | N/A |
| Completed | Computerized Alcohol Misuse Intervention System for Health Care NCT02368899 | Research Circle Associates, LLC | N/A |
| Completed | Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment NCT02966340 | University of Wisconsin, Madison | Phase 1 / Phase 2 |
| Completed | Aripiprazole for Bipolar Disorder and Alcohol Use Disorder NCT02918370 | University of Texas Southwestern Medical Center | Phase 3 |
| Completed | Oxytocin and Alcohol Withdrawal and Dependence NCT02903251 | Norwegian University of Science and Technology | Phase 3 |
| Completed | Individualized Assessment and Treatment for Alcoholism II NCT03233802 | UConn Health | N/A |
| Completed | Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU NCT02723383 | Nantes University Hospital | Phase 3 |
| Terminated | A Novel Compound for Alcoholism Treatment: A Translational Strategy - Part II NCT02707055 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Alcohol Addiction: A Systems-oriented Approach NCT02910193 | Charite University, Berlin, Germany | — |
| Completed | HIV & Drug Abuse Prevention for South African Men NCT02358226 | University of California, Los Angeles | Phase 3 |
| Completed | Trial of a Multi-pronged Intervention to Address Prevention of Violence in Zambia NCT02790827 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Withdrawn | Oxytocin in Alcohol Use Disorder NCT02711189 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 |
| Completed | Treatment Engagement With Technology-assisted Treatment NCT02674477 | Johns Hopkins University | N/A |
| Completed | Validation of a Test System for Development of Medications for Alcoholism NCT02652585 | Technische Universität Dresden | Phase 3 |
| Completed | The Effects of Oxytocin on Startle Hyperreactivity in Patients With AUD and PTSD NCT02469259 | University of California, San Francisco | EARLY_Phase 1 |
| Recruiting | Suicidal Behavior in Patients Diagnosed With Bipolar Disorder NCT02604277 | Emory University | N/A |
| Completed | New Therapeutic Strategies for Inhibitory Control in Alcoholism NCT03058276 | Hospital Universitario 12 de Octubre | N/A |
| Completed | New Therapeutic Strategies for the Treatment of Alcohol Use Disorders NCT03028662 | Gabriel Rubio Valladolid, MD | N/A |
| Completed | Usability Study for SOBERLINK System NCT02650180 | Soberlink Healthcare LLC | N/A |
| Completed | Evaluating Interventions for Alcohol Use Disorder NCT02409888 | Rutgers, The State University of New Jersey | N/A |
| Unknown | Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology NCT02759874 | Institute of Health Economics, Canada | N/A |
| Completed | Clinical Study of TripleA for Treatment of Alcohol Addiction in Outpatient Care NCT03195894 | Kontigo Care AB | N/A |
| Completed | Group Motivational Interviewing (GMI) For Homeless Veterans In VA Services NCT02233738 | VA Office of Research and Development | N/A |
| Terminated | Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults NCT00890149 | University of Maryland, Baltimore | Phase 2 |
| Unknown | Gut Hormones in Obesity, Nicotine and Alcohol Dependence NCT02690987 | Imperial College London | EARLY_Phase 1 |
| Completed | Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking- Randomised Controlled Pilot Trials NCT02327858 | University of Alberta | N/A |
| Terminated | Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity NCT02372318 | Central Institute of Mental Health, Mannheim | EARLY_Phase 1 |
| Completed | Laboratory Studies on Oxytocin for Treatment of Alcohol Use Disorder NCT02407340 | Johns Hopkins University | Phase 1 |
| Unknown | Retinoic Acid Homeostasis in Neuropsychiatric Diseases NCT02439099 | Charite University, Berlin, Germany | — |
| Completed | Adaptive Interventions for Problem Drinkers NCT02511808 | Northwell Health | N/A |
| Completed | ADHD: Gaps Between Patients With Alcohol-dependence and Impact on Relapse NCT02364817 | University Hospital, Lille | — |
| Completed | A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy D NCT02371889 | University of Pennsylvania | Phase 2 |
| Completed | The Role of Neural Systems for Emotion Regulation in Coping With Alcohol Craving NCT02316574 | New York State Psychiatric Institute | N/A |
| Completed | The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism NCT02262026 | Yale University | Phase 1 |
| Completed | The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues NCT02939352 | Medical University of South Carolina | EARLY_Phase 1 |
| Completed | Mifepristone Treatment of Alcohol Use Disorder NCT02179749 | The Scripps Research Institute | Phase 2 |
| Completed | Neural Substrates of Approach-Avoidance Conflict NCT02119624 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Sleep Disturbance and Relapse in Individuals With Alcohol Dependence: An Exploratory Mixed Methods Study NCT02181569 | National Institutes of Health Clinical Center (CC) | — |
| Recruiting | Characterization Imaging Instruments in Alcoholics and Non-Alcoholics NCT02108080 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Impact of a One-month Long Detoxification Diazepam Treatment on Early Alcohol Relapse NCT02242955 | University Hospital, Lille | N/A |
| Recruiting | Behavioral and Functional Task Development, Implementation, and Testing NCT02108054 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | N/A |
| Completed | Medication Development in Alcoholism: Investigating PPAR Agonists NCT02158273 | The Scripps Research Institute | Phase 2 |
| Completed | Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho NCT02126696 | Swiss Tropical & Public Health Institute | — |
| Recruiting | Ketamine Alcohol (in Treatment-Resistant Depression) NCT02122562 | Mark Niciu | Phase 2 |
| Unknown | Substance Dependence Satisfaction With Care and Quality Of Life NCT02894476 | Central Hospital, Nancy, France | — |
| Completed | Tailored Mobile Text Messaging to Reduce Problem Drinking NCT01885312 | Northwell Health | N/A |
| Completed | A Novel Compound for Alcoholism Treatment NCT02039349 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 |
| Completed | Efficacy and Safety of High Dose Baclofen for Alcohol Dependence NCT01980706 | University of North Carolina, Chapel Hill | Phase 2 |
| Terminated | Preventing Alcohol Withdrawal With Oral Baclofen NCT01937364 | Essentia Health | Phase 2 |
| Completed | Tidal Model's Effect on Coping and Self-Esteem NCT02604758 | Mahire Olcay Çam | N/A |
| Completed | A Study of LY2940094 in Participants With Alcohol Dependency NCT01798303 | BlackThorn Therapeutics, Inc. | Phase 2 |
| Completed | Project 4: Acute Effects of Alcohol on Learning and Habitization in Healthy Young Adults NCT01858818 | Technische Universität Dresden | — |
| Completed | ARCH Research Protocol for Provider Alcohol Pharmacotherapy Training and Assessment NCT02610517 | University of Alabama at Birmingham | N/A |
| Completed | Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics NCT01899521 | VA Office of Research and Development | N/A |
| Completed | Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients NCT01671501 | University of California, San Francisco | N/A |
| Completed | Transient Elastography in the Determination of Advanced Fibrosis in Alcoholic Liver Disease. NCT01789008 | Rennes University Hospital | N/A |
| Completed | ABT-436 for Alcohol Dependence NCT01613014 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Integrated Alcohol Disorder and PTSD Treatment NCT01601067 | VA Office of Research and Development | Phase 2 |
| Completed | Pregabalin for Alcohol Dependence NCT02205879 | St. Petersburg Bekhterev Research Psychoneurological Institute | Phase 4 |
| Completed | Integrated Stepped Care for Unhealthy Alcohol Use in HIV NCT01410123 | Yale University | N/A |
| Completed | Dutasteride Treatment for the Reduction of Heavy Drinking in Men NCT01758523 | UConn Health | Phase 4 |
| Completed | Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers NCT01779024 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK15 NCT01738867 | GlaxoSmithKline | Phase 1 |
| Completed | Baclofen for Treating Anxiety and Alcoholism NCT01751386 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Withdrawn | Deep Brain Stimulation for Refractory Alcoholism NCT01798888 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 |
| Completed | Varenicline Treatment of Alcohol Dependence in Smokers NCT01553136 | Yale University | Phase 2 |
| Terminated | Topiramate for Alcohol Use in Posttraumatic Stress Disorder NCT01408641 | University of Maryland, Baltimore | N/A |
| Completed | Consequences of At-risk Alcohol Consumption in ICU Patients NCT03565016 | Nantes University Hospital | — |
| Withdrawn | Pharmacogenetic Treatments for Alcoholism NCT01591291 | University of Virginia | Phase 2 / Phase 3 |
| Completed | Baclofen for the Treatment of Alcohol Drinkers NCT01604330 | Assistance Publique - Hôpitaux de Paris | Phase 2 / Phase 3 |
| Completed | Component Analysis for Motivational Interviewing NCT01642381 | Northwell Health | N/A |
| Completed | A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease NCT01504295 | Brown University | Phase 2 |
| Completed | Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists NCT01548417 | The Scripps Research Institute | Phase 2 |
| Completed | Trial Testing the Effect of Strategies on Performance of Brief Intervention Programmes for Harmful Alcohol Con NCT01501552 | Fundacion Clinic per a la Recerca Biomédica | N/A |
| Unknown | From Uncomplicated Alcoholism to Korsakoff's Syndrome NCT01455207 | University Hospital, Caen | N/A |
| Completed | Risperidone and Desipramine in Alcohol Use and Schizophrenia NCT01411085 | Dartmouth-Hitchcock Medical Center | Phase 2 |
| Unknown | Does Serum-DXM Increase Diagnostic Accuracy of the Overnight DXM Suppression Test in the Work-up of Cushing's NCT01504555 | Haukeland University Hospital | — |
| Completed | Overcoming Addictions: A Randomized Clinical Trial of a Web Application Based on SMART Recovery NCT01389297 | Behavior Therapy Associates, LLP | N/A |
| Withdrawn | Effect of JNJ 31001074 on Urge to Drink in Alcohol-Dependent Adults NCT01362699 | Janssen Research & Development, LLC | Phase 2 |
| Terminated | Genetics of the Acute Response to Alcohol in Social Drinkers NCT01375556 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 |
| Completed | GSK1521498 Alcohol Interaction Study NCT01366573 | GlaxoSmithKline | Phase 1 |
| Completed | Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alc NCT01904487 | Rajesh Narendran | Phase 1 |
| Terminated | Vigabatrin for Cocaine and Alcohol Dependence NCT01335867 | University of Pennsylvania | Phase 2 |
| Completed | Effects of Ghrelin on Alcohol Cue Reactivity and Craving NCT01190085 | Brown University | N/A |
| Completed | Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence NCT01528748 | University of Virginia | — |
| Completed | Varenicline for Alcohol Dependence NCT01146613 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Terminated | Varenicline and Alcohol in Inpatient Addictions Program (IAP) NCT01169610 | Mayo Clinic | Phase 3 |
| Completed | Dutasteride for the Reduction of Alcohol Use in Male Drinkers NCT01262287 | UConn Health | Phase 4 |
| Completed | Neural Mechanisms Underlying Alcohol Induced Disinhibition NCT01097213 | Technische Universität Dresden | — |
| Completed | Will Having Alcohol Treatment Improve Functioning? NCT01245647 | University of Florida | Phase 2 |
| Completed | Couples Therapy for Alcoholic Patients NCT01659957 | Harvard University | Phase 2 |
| Completed | N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence NCT01214083 | VA Office of Research and Development | Phase 2 |
| Completed | Project SERVE: Post Deployment Functioning NCT01123642 | VA Office of Research and Development | — |
| Completed | Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^ NCT01227980 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Ab NCT01414907 | Skane University Hospital | N/A |
| Completed | Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethan NCT01063166 | Technische Universität Dresden | — |
| Completed | Venue-Based Couples CoOp in South Africa NCT01121692 | RTI International | Phase 2 |
| Completed | Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot NCT01087736 | University of California, San Francisco | Phase 4 |
| Unknown | Brief Interventions in General Hospital (BIG) NCT00982306 | Partnerships in Care | Phase 1 |
| Completed | A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking NCT01076283 | Brown University | Phase 2 |
| Completed | Alcohol Interaction Study NCT01181908 | GlaxoSmithKline | Phase 1 |
| Completed | Alcohol Detoxification in Primary Care Treatment (ADEPT) NCT00855699 | University of Bristol | Phase 4 |
| Terminated | Assessing the Fit of Motivational Interviewing by Cultures With Adolescents NCT01948700 | University of New Mexico | N/A |
| Completed | Levetiracetam XR in Very Heavy Drinkers NCT00970814 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Unknown | Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury. NCT01326663 | Paul Saenger | N/A |
| Completed | The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD NCT00896038 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Terminated | Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism NCT00862563 | Boston Medical Center | Phase 2 |
| Withdrawn | Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Us NCT00871039 | Virginia Commonwealth University | Phase 4 |
| Terminated | Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants Wi NCT00764660 | Merck Sharp & Dohme LLC | Phase 2 |
| Unknown | Alcohol Addiction and Otorhinolaryngology Cancer NCT00825448 | Department of Clinical Research and Innovation | N/A |
| Completed | Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Accep NCT00760994 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Completed | The Teachable Moment: Screening and Brief Intervention for Admitted Trauma Patients NCT00865774 | Wake Forest University Health Sciences | N/A |
| Completed | Chronic Alcohol and Brain Stress Circuit Response NCT01031264 | Yale University | — |
| Completed | Imaging Cannabinoid CB1 Receptors in Alcohol Dependence NCT00816439 | National Institute of Mental Health (NIMH) | — |
| Completed | Ultra-brief Intervention for Problem Drinkers NCT00688584 | Centre for Addiction and Mental Health | N/A |
| Completed | Combining Medications for the Treatment of Alcohol Dependence: An Inpatient Preliminary Study NCT00769158 | Bankole Johnson | Phase 1 |
| Completed | Matching Genotypes and Serotonergic Medications for Alcoholism NCT01113164 | Brown University | Phase 1 |
| Completed | Valproate for Mood Swings and Alcohol Use Following Head Injury NCT01760785 | University of Colorado, Denver | N/A |
| Completed | Combined Pharmacotherapies for Alcoholism NCT00768508 | Bankole Johnson | Phase 3 |
| Completed | Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of He NCT00698464 | Novartis Pharmaceuticals | Phase 1 |
| Completed | High Dose Vitamin B1 to Reduce Abusive Alcohol Use NCT00680121 | University of Kansas | Phase 4 |
| Completed | Varenicline (Chantix™) for the Treatment of Alcohol Dependence NCT00705523 | University of Pennsylvania | Phase 2 |
| Completed | Acamprosate: Genes Associated With Response NCT00662571 | Mayo Clinic | — |
| Completed | GABRA2 and the Pharmacokinetics of Risk for Alcoholism (GPRA) NCT00681655 | Indiana University | N/A |
| Completed | The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion NCT00667771 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | EARLY_Phase 1 |
| Completed | Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis NCT00615862 | Virginia Commonwealth University | — |
| Completed | Naltrexone for Heavy Drinking in Young Adults NCT00568958 | Yale University | Phase 4 |
| Completed | Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics NCT00605904 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Study of the Medication Prazosin for Alcohol Dependence NCT00762710 | Seattle Institute for Biomedical and Clinical Research | Phase 2 |
| Completed | Seroquel for Frequent, Heavy Drinkers NCT00674765 | University of Pennsylvania | Phase 2 |
| Completed | Understanding Treatment Response With Naltrexone Among White Alcoholics NCT00817089 | University of Pennsylvania | Phase 4 |
| Completed | Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency NCT00498628 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | N-acetylcysteine in Alcohol Dependence NCT00568087 | Minneapolis Veterans Affairs Medical Center | Phase 1 / Phase 2 |
| Completed | Medication Development in Alcoholism: Acamprosate Versus Naltrexone NCT00656630 | The Scripps Research Institute | Phase 2 |
| Completed | Quetiapine vs. Placebo in Alcohol Relapse Prevention - a Pilot Study NCT00561587 | Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH | Phase 2 |
| Completed | The Stress-Hormone System in Alcohol-Dependent Subjects NCT00536146 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women NCT00127231 | Johns Hopkins University | N/A |
| Terminated | Cognitive Vulnerability Factors in Alcohol-dependence NCT02842528 | CHU de Reims | N/A |
| Completed | Cannabinoid Receptor Function & Alcoholism NCT00624715 | Yale University | Phase 1 |
| Completed | Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder NCT00572117 | Stanford University | Phase 4 |
| Completed | The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence NCT00434876 | Subhajit Chakravorty | Phase 3 |
| Completed | Effects of Alcohol on Simulated Driving NCT00477984 | Utrecht Institute for Pharmaceutical Sciences | N/A |
| Completed | Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment NCT00288886 | US Department of Veterans Affairs | Phase 2 |
| Completed | Pharmacogenetics of Alcohol: Treatment Implications NCT00734656 | UConn Health | N/A |
| Unknown | Antabuse in Severe Alcoholism: an Open Controlled Study NCT00431262 | Psykiatrisk Center Gentofte | Phase 4 |
| Unknown | Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence (ALC-DRD2-APO) NCT00437177 | Hospital Universitari Vall d'Hebron Research Institute | Phase 2 |
| Completed | OPRM1 A118G SNP, Alcohol Response, and Striatal Dopamine NCT00401999 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | The Effects of Zonisamide on Alcohol Dependence NCT00406692 | Boston University | Phase 2 |
| Completed | Alcohol Self Administration Laboratory NCT00398918 | Boston University | N/A |
| Completed | An Internet-based Intervention for Problem Drinking NCT00367575 | Centre for Addiction and Mental Health | N/A |
| Completed | Zonisamide vs. Placebo in the Treatment of Alcohol Dependence NCT00595556 | UConn Health | Phase 4 |
| Completed | Medication and Counseling for Controlled Drinking (Project SMART) NCT00444418 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 3 |
| Completed | Addiction Health Evaluation And Disease Management (AHEAD) Study NCT00278447 | Boston Medical Center | Phase 3 |
| Completed | Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects NCT00802321 | UConn Health | N/A |
| Completed | Effect of LY686017 on Alcohol Craving NCT00310427 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Terminated | Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism NCT00449007 | New York State Psychiatric Institute | Phase 4 |
| Completed | Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence NCT00142818 | Kyle Kampman | Phase 2 |
| Completed | Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety NCT00352469 | Creighton University | Phase 4 |
| Completed | The Effects of Levetiracetam on Alcohol Dependent Subjects NCT00325182 | Boston University | Phase 4 |
| Completed | Treatment of Patients With Alcoholism and Attention Deficit Disorder NCT00261872 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 4 |
| Completed | Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoh NCT00368862 | Finnish Institute for Health and Welfare | Phase 4 |
| Completed | Health Focused Motivational Treatment for Alcohol Dependent Veterans NCT00252590 | VA Office of Research and Development | N/A |
| Completed | GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence NCT00611767 | Yale University | N/A |
| Completed | 12-step Facilitation for the Dually Diagnosed NCT00583440 | University of New Mexico | Phase 1 / Phase 2 |
| Completed | Prazosin Alcohol Dependence IVR Study NCT00167687 | University of Washington | Phase 4 |
| Completed | New Medications to Treat Alcohol Dependence NCT00223639 | Bankole Johnson | Phase 2 |
| Completed | FMRI of Stress and Addictive Disorders NCT01558973 | Yale University | — |
| Completed | Using Telephone Technology to Prevent Relapse After Alcoholism Treatment NCT00132795 | University of Vermont | Phase 2 |
| Completed | Alcoholism Assessment and Treatment NCT00106093 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Unknown | Alcohol Dependency Study: Combining Medication Treatment for Alcoholism NCT00006205 | Bankole Johnson | Phase 2 |
| Completed | Acamprosate to Reduce Symptoms of Alcohol Withdrawal NCT00106106 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Completed | Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI) NCT00249405 | University of Cincinnati | Phase 2 |
| Completed | Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound NCT01208311 | Northwell Health | — |
| Completed | Clinical Trial With Ziprasidone for the Treatment of Psychiatric Pathology Associated to Alcoholism NCT00197951 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 3 |
| Completed | Simultaneous Measurement of Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) in P NCT00216905 | Ludwig-Maximilians - University of Munich | — |
| Unknown | Endocrine Regulation of Energy and Fluid Supplies in Alcoholic Patients NCT00447785 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | — |
| Completed | Topiramate for Alcohol and Cocaine Dependence NCT00167245 | Kyle Kampman | Phase 2 |
| Completed | Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms NCT00202514 | Seattle Institute for Biomedical and Clinical Research | Phase 2 / Phase 3 |
| Terminated | ALK21-006EXT: Long-term Safety of Medisorb® Naltrexone (VIVITROL®) in Alcohol- or Opioid-dependent Adults (Ext NCT00156936 | Alkermes, Inc. | Phase 3 |
| Completed | Serotonin Transporters in Alcoholism NCT00085865 | National Institute of Mental Health (NIMH) | — |
| Completed | Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients NCT00342563 | Yale University | Phase 2 |
| Terminated | Prazosin for ETOH or Cocaine Craving NCT00240227 | US Department of Veterans Affairs | N/A |
| Suspended | Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcohol NCT00226109 | University of Aarhus | Phase 4 |
| Completed | Study of Aripiprazole in Subjects With Alcoholism NCT00082199 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Phase 4 |
| Active Not Recruiting | Chicago Social Drinking Project NCT00961792 | University of Chicago | N/A |
| Completed | Levetiracetam for the Treatment of Alcohol Dependence and Anxiety NCT00141115 | New York State Psychiatric Institute | Phase 2 |
| Completed | An Efficacy and Safety Study of Topiramate in the Treatment of Alcohol Dependence NCT00210925 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 2 |
| Completed | Sertraline Pharmacotherapy for Alcoholism Subtypes NCT00368550 | UConn Health | Phase 4 |
| Completed | Gabapentin Treatment of Alcohol Dependence NCT00391716 | The Scripps Research Institute | Phase 2 |
| Completed | Health Behavior Feedback Study for Veterans With Hepatitis C NCT00229580 | University of Washington | Phase 1 |
| Completed | Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects. NCT00147576 | Pfizer | Phase 2 |
| Completed | ALK21-010: Long-term Safety of Medisorb® Naltrexone (VIVITROL®) in Alcohol-dependent Adults NCT00156923 | Alkermes, Inc. | Phase 3 |
| Completed | The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects NCT00329407 | Boston University | Phase 4 |
| Completed | Managing Alcoholism in People Who Do Not Respond to Naltrexone NCT00115037 | University of Pennsylvania | Phase 4 |
| Completed | Alcohol and Gender Effects on Stress Circuit Function NCT00226694 | University of Cincinnati | N/A |
| Completed | Improving Hepatitis C Treatment in Injection Drug Users NCT00148031 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Outpatient Treatment of Alcohol Withdrawal Syndrome NCT00136617 | Hvidovre University Hospital | Phase 3 |
| Completed | ALK21-006: Long-Term Study of Medisorb® Naltrexone (VIVITROL®) NCT01218997 | Alkermes, Inc. | Phase 3 |
| Completed | Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism NCT00338598 | Yale University | Phase 2 |
| Completed | Targeted Naltrexone for Problem Drinkers NCT00369408 | UConn Health | Phase 4 |
| Completed | Integrative Therapy in Alcoholism NCT00159107 | Heinrich-Heine University, Duesseldorf | Phase 4 |
| Completed | Naltrexone Treatment of Alcohol Abuse in Schizophrenia NCT00145847 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence. NCT00124059 | University of Pennsylvania | Phase 3 |
| Unknown | Trial for the Treatment of Alcohol Dependence NCT00120601 | University of Sydney | Phase 4 |
| Completed | Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline) NCT00000451 | Yale University | Phase 2 |
| Completed | Individually Adapted Therapy of Alcoholism NCT00317031 | Central Institute of Mental Health, Mannheim | Phase 4 |
| Completed | Outpatient Versus Inpatient Detoxification Program for Alcohol Dependent Patients Seeking Abstinence: The IN/O NCT00226720 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Clinical-Genetic Variation in GABA/Alcohol Sensitivity NCT00223444 | The University of Texas Health Science Center at San Antonio | — |
| Completed | Combination Nicotine Replacement for Alcoholic Smokers NCT00064844 | Yale University | Phase 4 |
| Completed | Trazodone for Sleep Disturbance in Early Alcohol Recovery NCT00027053 | Rhode Island Hospital | Phase 2 |
| Completed | Bupropion as a Smoking Cessation Aid in Alcoholics NCT00044434 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 4 |
| Completed | ALK21-003: Study of Medisorb® Naltrexone (VIVITROL®) in Alcohol-Dependent Adults NCT01218958 | Alkermes, Inc. | Phase 3 |
| Terminated | Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1 NCT00249431 | New York State Psychiatric Institute | Phase 2 |
| Completed | Naltrexone & SSRI in Alcoholics With Depression/PTSD NCT00338962 | Yale University | Phase 3 |
| Completed | Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron) NCT00027079 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Terminated | Alcoholism: Emotion and Thinking NCT00300638 | Boston University | — |
| Completed | Pharmacological Intervention Project (Fluoxetine) NCT00027378 | University of Pittsburgh | Phase 2 |
| Completed | Healthy Moms Alcohol Intervention NCT00244062 | University of Wisconsin, Madison | N/A |
| Completed | Ketamine/Placebo Family History Positive Study NCT00588952 | Yale University | N/A |
| Completed | Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of NCT00612352 | Yale University | N/A |
| Completed | Serotonin in Alcoholism NCT00011752 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) NCT00006489 | University of Pennsylvania | Phase 4 |
| Completed | Drug Treatment for Alcoholics With Bipolar Disorder NCT00000439 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Post-Treatment Effects of Naltrexone NCT00006449 | Indiana University | Phase 4 |
| Completed | Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine) NCT00006204 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 4 |
| Completed | Sertraline for Alcohol Dependence and Depression NCT00004554 | University of Pennsylvania | Phase 4 |
| Completed | Treating Alcohol Use In Older Adults With Depression NCT00018824 | US Department of Veterans Affairs | Phase 4 |
| Completed | Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse NCT00220597 | Stanford University | N/A |
| Completed | Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1 NCT00142844 | University of Pennsylvania | Phase 2 |
| Completed | Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch) NCT00004551 | Mayo Clinic | Phase 4 |
| Completed | Behavioral/Drug Therapy for Alcohol-Nicotine Dependence (Naltrexone/Nicotine Patch) NCT00000447 | The University of Texas Health Science Center, Houston | Phase 4 |
| Completed | Pharmacologic Relapse Prevention for Alcoholic Smokers NCT00000457 | Mayo Clinic | Phase 2 |
| Completed | Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1 NCT00218660 | University of Pennsylvania | Phase 3 |
| Completed | The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics NCT00001675 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence NCT00167232 | University of Pennsylvania | Phase 3 |
| Completed | Screening Evaluation for Studies of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) NCT00001673 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone) NCT00000437 | The Scripps Research Institute | Phase 4 |
| Completed | Timing of Smoking Intervention in Alcohol Treatment (Nicotine Patch) NCT00000444 | Minneapolis Veterans Affairs Medical Center | Phase 4 |
| Completed | COMBINE (Acamprosate/Naltrexone) NCT00006206 | University of North Carolina, Chapel Hill | Phase 3 |
| Completed | Naltrexone Maintenance Treatment of Alcoholism NCT00000450 | The Scripps Research Institute | Phase 4 |