NCT04552782

PTSD, AUD, and Interpersonal Conflict: Within-person Associations

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: University of South Dakota · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The present study seeks to increase understanding of Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD) among veterans, an important public health concern. We will study the effects of regulatory deficits and sleep disturbance on the dynamic course of PTSD and AUD. The study will investigate whether a short, computerized training in the laboratory will alter maladaptive response biases and reduce associations between sleep disturbance, affect and behavioral dysregulation, AUD symptoms, and PTSD symptoms in the real world.

Conditions

• Stress Disorders, Post-Traumatic
• Alcoholism

Interventions

Type	Name	Description
BEHAVIORAL	Alcohol CBM	Trains approach or avoidance responses to alcohol cues.
BEHAVIORAL	PTSD CBM	Trains approach or avoidance responses to trauma cues.
BEHAVIORAL	Alcohol Sham	Will not train approach or avoidance responses.
BEHAVIORAL	PTSD Sham	Will not train approach or avoidance responses.

Timeline

• Start date: 2020-12-04
• Primary completion: 2025-04-30
• Completion: 2025-04-30
• First posted: 2020-09-17
• Last updated: 2023-05-09

Locations

3 sites across 1 country: United States