NCT01553136

Varenicline Treatment of Alcohol Dependence in Smokers

1/2-Multi-site Study: Varenicline Treatment of Alcohol Dependent Smokers

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 131 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether varenicline is effective in the treatment of alcohol dependence in smokers.

Detailed description

Building upon knowledge about the role of nicotinic acetylcholine receptors in alcohol drinking and smoking, varenicline, a smoking cessation treatment that targets these receptors, will be tested as a potential treatment for alcohol dependent smokers seeking alcohol treatment.

Conditions

• Alcoholism
• Alcohol Abuse
• Smoking
• Alcohol Drinking

Interventions

Type	Name	Description
DRUG	Varenicline	0.5 mg once per day for Days 1 to 3, 0.5 mg twice per day for Days 4 to 7, then two 0.5 mg tablets (1 mg) twice per day

Timeline

• Start date: 2012-09-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2012-03-13
• Last updated: 2020-03-06
• Results posted: 2018-02-12

Locations

2 sites across 1 country: United States