Clinical Trials Directory

Trials / Sponsors / Royal Marsden NHS Foundation Trust

Royal Marsden NHS Foundation Trust

Academic / Other · 267 registered clinical trials45 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingIReC-Bio and IReC Registry
Head Cancer Neck
2026-04-01
Not Yet RecruitingImproving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Prostate Cancer
2026-02-28
RecruitingFeasibility of Serial Multisite Image-guided Biopsy to Study Breast Cancer Evolution
Breast Cancer, Metastatic Breast Cancer, Triple Negative Breast Cancer
2026-02-23
RecruitingAssessing a Digital Exercise Intervention for Health Outcomes and Engagement in Regular Exercise
Prostate Cancer, Prostate Cancer (Diagnosis)
N/A2025-12-16
Enrolling By InvitationCARDiac Toxicity Following ImmunOtherapy Treatment for Melanoma
Melanoma Stage III or IV
2025-09-26
WithdrawnMolecular Analysis of Gastric and OEsophageal Cancers STudy
Adenocarcinoma Esophagus, Adenocarcinoma of the Stomach, Adenocarcinoma - GEJ
2025-08-01
RecruitingFeasibility Study of Tissue and Blood Collection in Oncogene-addicted and Neoadjuvantly Treated Non Small Cell
Oncogene-addicted Non Small Cell Lung Cancer, Early-stage Operable Non Small Cell Lung Cancer, Non Small Cell Lung Cancer
2025-06-04
RecruitingPreoperative Planning With PSMA-PET in Melanoma Surgery Trial
Malignant Melanoma
Phase 22025-03-11
RecruitingZimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer
Locally Advanced Gastric Adenocarcinoma, MSI-H/dMMR Gastric Cancer, MSI-H/dMMR Gastroesophageal-junction Cancer
Phase 22025-02-20
RecruitingDose Escalated Radiotherapy for Rectal Cancers Using MR-guided Radiotherapy
Rectal Adenocarcinoma
N/A2025-02-14
Not Yet RecruitingPower of Liquid Biopsy Tracking in Immunotherapy Treated Stage IV Melanoma
Metastatic Melanoma
2025-02-01
RecruitingDose dE-eScalaTion IN prostATe radIOtherapy usiNg an MR-Linac in 2 Fractions
Prostate Cancer
N/A2025-01-20
Not Yet RecruitingLATe TreatmENT Related Toxicity in Melanoma (LATENT)
Melanoma
2024-12-01
Not Yet RecruitingBody Composition in Older Adults
Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia, Body Composition Changes
2024-11-01
RecruitingMIBREAST Making in Immediate Breast REconstruction And the Measurement of the EffectS of RadioTherapy
Breast Cancer
2024-09-12
Not Yet RecruitingGene Expression Profiling in a Validation Cohort of Locally Advanced and Recurrent/Metastatic Salivary Gland C
Salivary Gland Cancer
2024-09-01
Enrolling By InvitationProphylactic Prostatectomy for Prostate Cancer (PPPC)
Prostate Cancer, Genetic Predisposition to Disease, BRCA Mutation
2024-06-24
RecruitingThe EMIRATES Study
Differentiated Thyroid Cancer (DTC)
2024-06-19
RecruitingBreast Cancer Evolution During Neoadjuvant Systemic Therapy
Breast Cancer, Triple Negative Breast Cancer, ER+ Breast Cancer
2024-05-29
RecruitingVideo Capsule Examination in Patients With Lynch Syndrome
Lynch Syndrome, Li Fraumeni Syndrome, PTEN Hamartoma Syndrome
N/A2024-03-04
UnknownUse of Artificial Intelligence in the Symptomatic BReAst Clinic SEtting
Cancer, Breast
2024-03-01
RecruitingSingle and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer
Cancer Head Neck
2023-12-19
UnknownPelvic Radiation Disease in Childhood Cancer Survivors
Radiation Disease
2023-10-01
Not Yet RecruitingIMaC - Immune Pathways in Oesophagogastric Cancer
Oesophagogastric Cancer
2023-10-01
UnknownFat Grafting for Vaginal Stenosis in Gynaelogical Cancer
Cervical Cancer
N/A2023-10-01
Active Not RecruitingImpact of Apalutamide in Metastatic Hormone Sensitive Prostate Cancer Patients
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
2023-09-26
RecruitingCLIMB: CNS Lymphoma Imaging and Molecular Biomarkers Study
CNS Lymphoma
2023-09-18
RecruitingThe RESCUE Study: Survival and Functional Outcomes Following Salvage Surgery for RESidual or reCurrent sqUamou
Head and Neck Cancer
2023-09-08
Not Yet RecruitingSepsis in Oncology Patients
Sepsis in Cancer Patients
2023-09-01
RecruitingRDC Biomarker Study
Cancer
2023-07-10
RecruitingSafe De-escalation of Chemotherapy for Stage 1 Breast Cancer
Breast Cancer
N/A2023-06-05
UnknownA Study Comparing Urolift and TURP Ahead of Radiotherapy in Men With Urinary Symptoms Secondary to Prostate En
Prostate Cancer
N/A2023-05-09
CompletedThe Role of tHyroid cAncer Specific Patient Concerns iNventory (PCI-TC) in Enhancing Shared decisiOn Making
Thyroid Cancer
2023-05-03
RecruitingPartial Volume High-Dose Irradiation in Renal Cell Carcinoma for Intra-TUmoural Control ALongside Current Mana
Renal Cell Carcinoma, Renal Cell Carcinoma Metastatic
N/A2023-03-27
RecruitingInvestigating Utility of ctDNA and Tumour Evolution in Advanced Thyroid Cancer
Thyroid Cancer
2023-03-23
UnknownEVEREST-HN 1: EVolution of a patiEnt-REported Symptom-based Risk Stratification sySTem
Head and Neck Cancer
2023-03-17
RecruitingDose De-escalation in Prostate Radiotherapy Using the MRL
Prostate Adenocarcinoma
N/A2023-03-01
UnknownAssessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Col
Hepato-Biliary Carcinoma in Situ Nos, Pancreatic Cancer, Colorectal Cancer
2023-03-01
RecruitingLiquid Biopsy for Early DiagNosis of Squamous Cell Carcinoma of the HeAd and NeCk rEgion
Head and Neck Squamous Cell Carcinoma
2023-02-01
Active Not RecruitingFulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Su
Metastatic Breast Cancer, ER+ Breast Cancer, Advanced Breast Cancer
Phase 22022-12-28
UnknownHaemorrhage Risk Reduction Using Endovascular Embolisation in Place of Vessel Ligation for Patients Undergoing
Head and Neck Cancer
N/A2022-08-01
UnknownPINPOINT Feasibility Study
Prostate Cancer, Image Guided Radiotherapy
N/A2022-08-01
UnknownInherited Cancer Early Diagnosis (ICED) Study
Li Fraumeni Syndrome, Lynch Syndrome, Hereditary Diffuse Gastric Cancer
2022-07-26
UnknownBiological Characteristics of Older Women (> 70 Years) With ER Positive, HER2 Negative Early Breast Cancer
Breast Cancer Female
2022-07-21
CompletedRandomised Study to Investigate the Effectiveness of Acupuncture for the Relief of Long COVID-19 Related Fatig
COVID-19
Phase 22022-07-19
UnknownAccelerated Body Diffusion-Weighted MRI Using Artificial Intelligence
Cancer
2022-05-06
UnknownPorto-Venous Radiomics in Pancreatic Cancer
Pancreatic Cancer
2022-05-05
CompletedMapping Arterial Perforators Within the Breast During Mammoplasty
Breast Cancer
2022-04-27
RecruitingThe Man Van Project
Prostate Cancer, Urologic Cancer, Urologic Diseases
N/A2022-04-13
RecruitingUnderstanding immunE-related toXicities by multifACeT Profiling
Oncology
2022-04-06
RecruitingORganoid GeneratioN Study for Cancer
Cancer
2022-04-04
RecruitingA Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palboc
ER+ Breast Cancer, HER2-negative Breast Cancer
Phase 22022-03-30
RecruitingExploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the H
Head and Neck Cancer
2022-03-09
RecruitingPrecision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients
Sarcoma, Sarcoma, Leiomyo-, Adult, Sarcoma, Synovial, Adult
2021-11-19
CompletedChanges to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurren
Recurrent Oropharynx Carcinoma
2021-10-27
UnknownPRELUDE Study of Lymphatic Surgery to Treat Breast Cancer Related Lymphoedema
Breast Cancer, Lymphedema
N/A2021-10-13
RecruitingAI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer
Indeterminate Pulmonary Nodules, Lung Metastases, Second Primary Cancer
2021-10-13
UnknownSingle Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical
Head and Neck Squamous Cell Carcinoma
2021-09-02
UnknownImproving Diagnosis and Treatment of Metastatic Advanced Prostate Cancer
Advanced Prostate Carcinoma
2021-07-30
UnknownBreast-implant ASsocIated anaplastIc Large Cell Lymphoma and CApsular Contracture
Breast Implant-Associated Anaplastic Large Cell Lymphoma, Capsular Contracture, Implant, Breast Implant; Complications
2021-07-27
RecruitingEvaluation of New Magnetic Resonance Techniques
Magnetic Resonance Imaging
2021-04-21
RecruitingPredicting Radiotherapy Response and Toxicities in Soft Tissue Sarcoma of the Extremities - Cohort B
Soft Tissue Sarcoma of the Extremities
2021-04-16
RecruitingNodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study
Lung Cancer
2021-04-07
TerminatedPembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma
Advanced Malignant Pleural Mesothelioma
Phase 12021-02-12
CompletedOptimising Cancer Therapy And Identifying Causes of Pneumonitis USing Artificial Intelligence (COVID-19)
Lung Cancer, Covid19, Pneumonitis
2021-01-27
CompletedInformation Needs Around Parenteral nUTrition in Cancer
Cancer, End Stage Cancer, Terminal Cancer
2021-01-19
UnknownMulti -paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases
Brain Metastases, Adult
2020-12-01
RecruitingExploratory Study of Clonal Evolution in Cancer for Patients Undergoing Transoral Robotic Surgery for Radiatio
Head and Neck Cancer
2020-11-18
Unknown'Lung Health Check' Biomarker Study
Lung Cancer, Cancer
2020-09-28
UnknownPIONEER Study of Lifestyle Intervention to Reduced Breast Cancer Risk
Breast Cancer, Lifestyle Risk Reduction
N/A2020-09-16
RecruitingPAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer
Triple Negative Breast Cancer, Locally Advanced Breast Cancer, Recurrent Breast Cancer
Phase 12020-08-11
UnknownOncotype DX DCIS: Impact on Radiotherapy Decision Making
Breast Cancer
N/A2020-07-07
WithdrawnCombination Nab-paclitaxel (N-P) and Nintedanib or N-P and Placebo in Relapsed NSCLC Adenocarcinoma
NSCLC, Recurrent, Adenocarcinoma of Lung
Phase 1 / Phase 22020-07-01
UnknownFeasibility of Wearable Activity Trackers for Detection of TOXicity in People Receiving Systemic Anticancer Tr
Lung Cancer, Small Cell, Pancreatic Cancer, Gastric Cancer
2020-07-01
UnknownImproving Cyberknife Spinal Stereotactic Radiotherapy in Difficult to Treat Cases (IMPRESS)
Solid Tumor, Adult
N/A2020-07-01
UnknownImproving Informed Consent for Early Phase Anti-Cancer Trials
Solid Neoplasms
N/A2020-06-26
CompletedPreventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsie
Neoplasm, Colorectal, Neoplasm of Lung, Neoplasm, Bladder
2020-06-18
UnknownInvestigating National Solutions for Personalised Iodine-131 Radiation Exposure
Differentiated Thyroid Cancer
2020-06-17
UnknownLung Nodule Imaging Biobank for Radiomics and AI Research
Lung Cancer, Pulmonary Nodule, Multiple, Pulmonary Nodule, Solitary
2020-06-01
UnknownFeasibility of Frailty Assessment and Implementation of Interventions in Women Over 70 With Epithelial Ovarian
Ovarian Cancer, Chemotherapy, Quality of Life
N/A2020-06-01
CompletedCancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19)
Infectious Disease, Cancer, Coronavirus Infection
2020-05-26
CompletedTransoral Robotic Surgery for rECurrent Tumours of the Upper Aerodigestive Tract
Recurrent Head and Neck Cancer
2020-02-14
Active Not RecruitingWaKING: Wnt and checKpoint INhibition in Gastric Cancer
Metastatic Esophageal Cancer, Metastatic Gastric Cancer
Phase 1 / Phase 22020-02-11
UnknownMulti-Centre Observational Study of Maintenance Niraparib in Treatment of Ovarian CanceR
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
2020-02-03
Active Not RecruitingEvaluation of Tongue Base MucOsectomy & Step sErial Sectioning
Squamous Cell Carcinoma of the Oropharynx
2019-11-01
UnknownGeneration Of a Lung Biobank for Future Use
Cancer, Lung Cancer
2019-10-31
UnknownOptimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Bio
Head and Neck Cancer
Phase 1 / Phase 22019-10-23
UnknownWhole Body Magnetic Resonance Imaging Study
Advanced Prostate Cancer
2019-10-09
UnknownEvaluating a Digital Tool for Supporting Breast Cancer Patients
Breast Cancer
N/A2019-10-01
UnknownExploratory Study of Molecular Characterization in Patients With Metastatic Germ Cell Tumours Refractory/Resis
Testicular Germ Cell Tumor
2019-08-01
UnknownA Translational Study of Single Agent Olaparib in the Treatment of Advanced Oesophagogastric Cancer
Oesophageal Cancer, Gastro-Oesophageal Junction Cancer, Gastric Cancer
Phase 22019-07-02
UnknownEvaluation of an Educational Intervention for Women With Breast Pain
Breast Pain, Mastalgia
N/A2019-05-31
CompletedCrizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid
Lobular Breast Carcinoma, Gastric Cancer, Triple Negative Breast Cancer
Phase 22019-05-09
UnknownThe Effect of ENZAlutamide on the Anti-Xa Levels of Patients Receiving DOACs
Drug Interaction
2019-05-01
Active Not RecruitingiSCORE: Immunotherapy Sequencing in COlon and REctal Cancer
Metastatic Colorectal Cancer
Phase 22019-03-27
UnknownLifestyle Changes Using Digital Technology in Colorectal Cancer
Life Style, Colo-rectal Cancer
N/A2019-03-18
CompletedMen's Experience of Prostate Biopsy
Prostate Biopsy
2019-01-25
UnknownEpigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE)
Cancer, GI Cancer
Phase 22019-01-11
UnknownA Prospective Translational Tissue Collection Study in Early and Advanced Pancreatic Ductal Adenocarcinoma and
Pancreatic Adenocarcinoma
2019-01-10
CompletedPhase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma
Soft-tissue Sarcoma
Phase 1 / Phase 22018-11-05
RecruitingValue of Analysing Under-utilised Leftover Tissue (VauLT)
Oncology
2018-09-10
WithdrawnA Phase Ib Combination Study of Rituximab, TinostamustinEAnd CHeckpoint Inhibition With Pembrolizumab in Relap
Relapsed or Refractory Diffuse Large B-cell Lymphoma
Phase 12018-09-01
TerminatedAvelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer
POLE Exonuclease Mutant Colon Cancer, Microsatellite Instability, Stage III Colon Cancer
Phase 32018-08-31
UnknownGustatory Function Following Radiotherapy to the Head and Neck
Head and Neck Cancer
2018-08-29
UnknownGamma Delta T Cells in AML
Acute Myeloid Leukemia
2018-08-23
UnknownTargeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients.
Prostate Cancer, Metastasis, Toxicity Due to Radiotherapy
N/A2018-08-13
UnknownProstate Radiotherapy Integrated With Simultaneous MRI (The PRISM Study)
Prostate Cancer
N/A2018-08-07
UnknownMachine Learning in Myeloma Response
Myeloma
N/A2018-07-04
CompletedSimplification of Low Level Internal Dosimetry
Exposure to Medical Diagnostic Radiation
2018-06-30
CompletedTITAN (Tumoural Injection of T-VEC and Isolated Limb Perfusion)
Melanoma and Sarcoma
Phase 1 / Phase 22018-06-26
UnknownLab-on-a-chip Detection of Cervical Cancer Tumour Markers
Cervical Cancer
2018-04-01
TerminatedPembRolIzuMab and Stereotactic Body Radiotherapy In Metastatic Non-small-cell lunG Cancer Patients
Metastatic Non-small-cell lunG Cancer
Phase 12018-03-01
UnknownRadiation Exposure Awareness From Patients Undergoing Nuclear Medicine Diagnostic Scans
Skeletal Scintigraphy, FDG PET/CT
2018-02-26
UnknownHRQoL in Advanced Soft Tissue Sarcoma Patients Treated With Chemotherapy.
Quality of Life
2018-02-23
CompletedSBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects
Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage I
Phase 1 / Phase 22018-02-08
TerminatedA Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer
Cervix Cancer
Phase 12017-12-21
CompletedMR-guided RAdiotherapy to Breast With Dose Escalation to regionaL Lymph NodEs
Breast Cancer
N/A2017-12-18
CompletedPembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma
Sarcoma
Phase 1 / Phase 22017-11-29
UnknownLondon Investigation Into diElectric Scanning of Lesions
Breast Cancer
N/A2017-11-01
UnknownStudy Title: Peri-operative Immuno-Chemotherapy in Operable Oesophageal and Gastric Cancer
Gastric Adenocarcinoma, Oesophageal Adenocarcinoma
Phase 22017-07-31
UnknownBlood Immunophenotyping in Staging of Indolent B-cell Lymphomas V1.0
Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL)
2017-07-19
TerminatedPEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma
Phase 12017-07-12
UnknownPilot Study for 3-Dimensional Surface Imaging in Implant-based Breast Reconstruction
Breast Cancer
2017-06-09
CompletedSurgical Anatomy and 'Waisting' of the sIgmoid SpEcimen
Sigmoid, Sigmoid Colon, Neoplasm, Cancer
2017-05-18
UnknownImproving Diagnosis in Idiopathic Cytopenia Using Gene Sequencing
Cytopenia
2017-05-05
UnknownSimulating Outcomes From Breast Conserving Surgery Using 3D Surface Imaging
Breast Cancer Female
N/A2017-05-01
UnknownLaboratory Studies Into the Pathology of Leukaemia
Leukemia
2017-04-24
CompletedMagnetic Resonance Breast Tissue Characterisation to Improve Risk Stratification for Breast Cancer
BRCA1 Mutation, BRCA2 Mutation, Mammography
2017-03-13
UnknownA Trial Assessing Post-Operative Use of ProSpare, a Rectal Obturator in Prostate Cancer Radiotherapy
Cancer
Phase 22017-02-08
RecruitingCombination Study of Guadecitabine/ASTX727 and Pembrolizumab
Non Small Cell Lung Cancer
Phase 12017-01-26
CompletedThe HeartSpare Plus 1B Trial
Breast Cancer
Phase 22016-12-12
RecruitingTracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer
Colorectal Cancer
2016-12-05
UnknownConventional Care Versus Radioablation (Stereotactic Body Radiotherapy) for Extracranial Oligometastases
Prostate Cancer, Breast Cancer, Carcinoma, Non-Small-Cell Lung
Phase 2 / Phase 32016-11-01
Active Not RecruitingEnhancing Diagnosis in Chronic B-cell Lymphoproliferative Disorders Using Next-Generation Sequencing
Lymphoma
2016-08-01
UnknownProof-of-concept Study of Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma
Gastrooesophageal Cancer
Phase 22016-07-19
CompletedPembrolizumab and Palliative Radiotherapy in Lung
Thoracic Tumours
Phase 12016-06-24
Active Not RecruitingPembrolizumab in Muscle Invasive/Metastatic Bladder Cancer
Invasive Bladder Cancer
Phase 12016-06-06
UnknownTenovus Cancer Choirs Study: the Benefits of Singing for Those Affected by Cancer
Cancer
N/A2016-04-01
CompletedEvaluation Of CanADVICE+®M-Health System To Support Breast Cancer Patients Receiving Capecitabine
Metastatic Breast Cancer
N/A2016-03-16
UnknownDeveloping a Symptom List for Children With Cancer
Paediatric Oncology Palliative Care
2016-03-01
TerminatedTrial of Pembrolizumab and Radiotherapy in Melanoma
Melanoma
Phase 22016-02-01
CompletedPrimary Radiotherapy And DIEP flAp Reconstruction Trial
Breast Cancer
N/A2016-01-14
UnknownImpact of Radiotherapy on Patients Undergoing DIEP Flap Breast Reconstruction
Breast Cancer
2016-01-14
WithdrawnA Study of Anti-PD-1 (Pembrolizumab) Therapy in Metastatic Melanoma (ADAPTeM)
Advanced Melanoma
Phase 22016-01-01
UnknownThe Effect of an Aromatherapy Intervention on Sleep in the ICU
Sleep Deprivation
N/A2016-01-01
CompletedGI Consequences Economic Evaluation
Cancer
2016-01-01
UnknownIdentification of Molecular Biomarkers for Thyroid Cancer
Thyroid Cancer
2015-12-21
UnknownUsing an Electronic Nose to Predict Gastrointestinal Consequences of Pelvic Radiotherapy
Cancer, Toxicity, Malignancy
2015-11-01
CompletedComparing Immobilisation Shells in Cranial Radiotherapy
Brain Metastases, Bone Metastases, Brain Tumor, Primary
N/A2015-11-01
UnknownGynaecologic Organ Segmentation and Motion Tracking Using Ultrasound
Cervical Cancer
2015-09-01
UnknownMri IN STaging REctal Polyp Planes
Rectal Cancer, Rectal Neoplasms, Colonic Polyps
N/A2015-08-13
CompletedStudy of PRoliferation and Apoptosis in Rectal Cancer, Predictive & Prognostic biOmarkers: Histopathology and
Neoplasms, Colorectal Neoplasms, Rectal Diseases
2015-06-01
UnknownArt Therapy for Pain Relief in Breast Cancer Patients
Pain
2015-06-01
CompletedA Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)i
Melanoma, Cancer
Phase 12015-04-15
UnknownThe Use of 3D Surface Imaging in the Objective Assessment of Breast Conserving Therapy
Breast Cancer
2015-04-01
TerminatedA Study of Anti-PD1 (Nivolumab) Therapy as Pre- and Post-operative Therapy in Metastatic Renal Cell Cancer (AD
Renal Cell Carcinoma
Phase 22015-04-01
CompletedPIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib
Advanced Solid Tumours, Breast Cancer
Phase 12015-03-25
Active Not RecruitingPlanning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial
Adenocarcinoma of the Oesophagus, Adenocarcinoma of the Gastro-oesophageal Junction, Adenocarcinoma of the Stomach
Phase 22015-02-01
CompletedProspective Translational Study Investigating Molecular Predictors of Resistance and Response to Regorafenib M
Metastatic Colorectal Cancer
2015-01-01
CompletedPPALM-Palm Oil and Pentoxifylline Against Late Morbidity
Long-term Adverse Effects of Radiotherapy for Pelvic Cancer
Phase 22014-11-25
UnknownTissue Collection for Biomarkers Determining Resistance to Ibrutinib
Mantle Cell Lymphoma, Chronic Lymphocytic Leukaemia
2014-10-01
UnknownPhase I Study to Assess Safety of AZD6738 Alone and in Combination With Radiotherapy in Patients With Solid Tu
Solid Tumour Refractory to Conventional Treatment
Phase 12014-07-01
UnknownDevelopment of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surger
Persistent Post-surgical Pain, Neuropathic Pain, Cancer Pain
N/A2014-06-01
CompletedThe FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms"
Cancer
2014-04-01
CompletedTrial of Olaparib in Combination With AZD5363 (ComPAKT)
Advanced Cancer
Phase 12014-03-31
UnknownRapid Medical Donation Programme for Breast Cancer
Metastatic Breast Cancer
2014-03-01
UnknownFeasibility of a Molecular Characterisation Approach to Treatment
Advanced Gastrointestinal Cancers
2014-02-01
UnknownInternational Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Week
Squamous Cell Carcinoma of the Anus
Phase 22013-12-01
UnknownPhase II Study Comparing LR-GEM to R-GEM-P in Second-line Treatment of Diffuse Large B-cell Lymphoma (LEGEND)
Diffuse Large B-Cell Lymphoma
Phase 22013-09-01
CompletedPhase I Trial of ONX-0801 Once Weekly or Alternate Weekly
Solid Tumours
Phase 12013-09-01
CompletedPhase I Trial of VS-6766 Alone and in Combination With Everolimus
Solid Tumours, Multiple Myeloma, Lung Cancer
Phase 12013-06-17
UnknownMolecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous In
Adenocarcinoma, Rectal Diseases, Colorectal Neoplasms
2013-06-07
UnknownThe SPARC Trial: Stereotactic Prostate Ablative Radiotherapy Using Cyberknife
Prostate Cancer
Phase 22013-06-01
CompletedA Phase I Trial of the Combination of AZD2014 and Weekly Paclitaxel.
Advanced Cancer
Phase 12013-04-26
CompletedPROSPECT-C: A Study of Biomarkers of Response or Resistance to Anti-EGFR Therapies in Metastatic Colorectal Ca
Metastatic Colorectal Cancer
2012-11-01
UnknownIncidence of Postoperative Ketosis and Metabolic Acidosis
Metabolic Acidosis
2012-10-01
UnknownProof-of-Concept Study of AZD4547 in Patients With FGFR1 or FGFR2 Amplified Tumours
Gastric Cancer, Oesophageal Cancer, Breast Cancer
Phase 22012-09-01
Active Not RecruitingProstate Advances in Comparative Evidence
Prostate Cancer
Phase 32012-08-07
UnknownCHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study
Peripheral T-cell Lymphoma NOS, Anaplastic Large Cell Lymphoma, ALK-Negative, Angioimmunoblastic T-cell Lymphoma
Phase 22012-03-01
UnknownTRACERx Renal CAPTURE Sub-study
Renal Cell Carcinoma, Cancer, Healthy Volunteers
2012-02-05
CompletedThe HeartSpare Study (Stage I)
Breast Cancer
Phase 2 / Phase 32012-02-01
CompletedA Cross-sectional Study Looking at the Effect of Radiotherapy on Carotid Intima-medial Thickness in Head and N
Head and Neck Tumours
2011-10-01
UnknownA Prospective Longitudinal Cohort Study Looking at the Difference in Carotid Intima-medial Thickness Between I
Head and Neck Tumours
2011-10-01
UnknownEvaluation of the Hospital2Home Palliative Care Service for Patients With Advanced Progressive Lung Disease
Lung Disease
Phase 22011-10-01
CompletedA Survivorship Care Plan for Gynaecological Cancer Patients
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer
2011-08-01
CompletedValidation of a Nutrition Screening Tool
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer
2011-07-01
UnknownPain: Screen and Treat
Head and Neck Cancer, Pain
Phase 32011-01-01
CompletedReflexology or Aromatherapy Massage in Relieving Symptoms in Patients With Cancer
Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
N/A2010-10-01
UnknownThe Use of a Quality of Life Questionnaire in Patients With Lung Cancer
Lung Cancer
N/A2010-09-01
CompletedComparison of the Diagnostic Accuracy of 3D Volume Acquisition MRI With CT in Staging Colonic Cancer
Colon Cancer
2010-08-18
CompletedStudy of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gas
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer
2010-08-01
CompletedChemotherapy Induced Painful Peripheral Neuropathy Ethosuximide (The CIN-E Study)
Cancer, Peripheral Neuropathy
Phase 22010-05-01
UnknownPhase II Study of Whole or Partial Parotid Sparing Intensity Modulated Radiotherapy in Patients With Head and
Head and Neck Cancer
2010-03-01
UnknownOptimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks
Adenocarcinoma of the Rectum, Adenocarcinoma, Adenocarcinoma, Mucinous
Phase 22009-10-16
CompletedLow-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy fo
Anal Cancer, Bladder Cancer, Cervical Cancer
N/A2009-10-01
UnknownAn Exploration of Genetic Testing for Prostate Cancer Susceptibility
Prostate Cancer
2009-08-01
UnknownEvaluation of Bladder Volumes in Patients Receiving Radiotherapy to the Rectum, Using Kilovoltage Cone-beam Im
Rectal Cancer
2009-05-01
CompletedPain Prevalence and Risk Factors Among Sarcoma/Melanoma Oncology Patients in an Outpatients Setting
Sarcoma, Melanoma
2009-05-01
CompletedThe Physiological Response to Routine Head and Neck Cancer Surgery
Head and Neck Cancer
2009-05-01
TerminatedA Clinical Study of UFT/Leucovorin, Radiotherapy With or Without Cetuximab Following Induction Gemcitabine Plu
Pancreatic Cancer
Phase 22009-03-01
UnknownMultifunctional Magnetic Resonance (MR) for Radiotherapy Planning in Prostate Cancer
Prostate Cancer
N/A2009-03-01
TerminatedMethotrexate in Metastatic Colorectal Cancer With MSH2 Deficiency
Advanced Colorectal Cancer
Phase 22009-02-01
UnknownPatient Satisfaction in the Critical Care Unit: A Qualitative Phenomenological Study
Patient Satisfaction in the Critical Care Unit
2009-02-01
UnknownFunctional Imaging in HNC Undergoing Chemoradiation
Head and Neck Cancer
2009-02-01
UnknownAdaptive Planning in Bladder Cancer
Bladder Cancer
Phase 22009-01-01
UnknownHyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy i
Bladder Cancer, Cervical Cancer, Colorectal Cancer
Phase 32009-01-01
UnknownAnalysis of Pharmacodynamic Changes With AUY922A, an HSP90 Inhibitor
Advanced Solid Malignancies
2008-12-01
CompletedNovel Prognostic Markers in Renal Cancer
Renal Cell Carcinoma
2008-12-01
UnknownThe Identification of Novel Prognostic Markers in Melanoma
Malignant Melanoma
2008-12-01
UnknownSS-GCC1- Screening Study of Genetic Changes in Colorectal Cancer
Colorectal Cancer
2008-11-01
CompletedSuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy)
Breast Cancer
Phase 32008-11-01
CompletedMeasurement of the Folate Receptor in Blood
Healthy
2008-09-01
UnknownEvaluation of Stents to Open Restricted Airways in Patients With Centrally Placed Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Phase 32008-09-01
CompletedFR in Stored Plasma
Ovarian Cancer
2008-07-01
CompletedEducational Follow-up in a Cohort of Children at the Royal Marsden Hospital (RMH)
Brain Tumour
2008-06-01
TerminatedREAL3 Trial of Efficacy of EOX With/Without Panitumumab in Previously Untreated Adv OG Cancer
Oesophago-gastric Cancer
Phase 32008-05-01
UnknownRadioiodine Dosimetry Protocol for Thyroid Cancer Metastases
Thyroid Carcinoma, Metastatic Sites Lung Bone Nodal
N/A2008-05-01
TerminatedR-CHOP-B Bevacizumab for Diffuse Large B Cell Lymphoma
Non-Hodgkin's Lymphoma, B-cell Lymphoma
Phase 22008-05-01
CompletedRadiation Therapy Planning Techniques in Reducing Damage to Normal Tissue in Women Undergoing Breast-Conservin
Breast Cancer
N/A2007-11-01
UnknownMultifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Bre
Breast Cancer
N/A2007-11-01
UnknownLow Rectal Cancer Study (MERCURY II)
Adenocarcinoma, Adenocarcinoma, Mucinous, Carcinoma
2007-08-13
CompletedA Study of Intensity-modulated Radiotherapy in Patients With Squamous Cell Carcinoma of Unknown Primary (SCCUP
Head and Neck Cancer
N/A2007-07-01
CompletedCare of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis
Cancer
N/A2007-04-01
UnknownEvaluation of Group CBT Programme With Breast Cancer Patients
Breast Cancer
2007-01-01
UnknownPartial Liver Radiotherapy for Unresectable Liver Metastases
Metastatic Colorectal Liver Cancer
N/A2006-11-01
CompletedGemcitabine and Oxaliplatin (Gem-Ox) Plus Glivec in Gemcitabine-refractory Pancreatic Cancer
Advanced Pancreatic Cancer
Phase 12006-07-01
UnknownAvoiding Surgery in Rectal Cancer After Pre-Operative Therapy
Rectal Adenocarcinoma
Phase 22006-06-06
UnknownModelling Internal Hepatic Movement With an External Abdominal Marker
Patients With Liver Metastases From Colorectal Cancer
2006-06-01
CompletedCapecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only M
Metastatic Colorectal Cancer
Phase 22006-06-01
UnknownFollow-up Evaluation Using CT Scans in Patients Who Have Been Treated For Metastatic Testicular Cancer
Testicular Germ Cell Tumor
2006-04-01
CompletedParotid-sparing IMRT for Nasopharyngeal Cancer
Nasopharyngeal Cancers, Intensity Modulated Radiotherapy With Chemotherapy
2006-02-01
CompletedCombining Erlotinib Plus Bevacizumab and Gemcitabine Plus Capecitabine to Treat Advanced Pancreatic Cancer
Pancreatic Cancer
Phase 1 / Phase 22005-11-01
UnknownOxaliplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients Undergoing Sur
Colorectal Cancer
Phase 22005-09-01
CompletedA Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and Neck
Oropharyngeal Squamous Cell Cancer, Hypopharyngeal Squamous Cell Cancer
2005-07-01
CompletedPhase II Fixed Dose Rate Gemcitabine for Advanced or Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22004-05-01
UnknownParotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating
Head and Neck Cancer, Radiation Toxicity, Xerostomia
Phase 32004-01-01
CompletedNipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing
Breast Cancer
N/A2003-11-01
CompletedMolecular Markers of Prognosis in Colorectal Cancer Patients
Colorectal Cancer
2003-11-01
UnknownDuct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast C
Breast Cancer
Phase 22003-10-01
UnknownNipple Aspiration, Ductal Lavage, and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for
Breast Cancer
Phase 22003-09-01
CompletedProspective Study in Pelvic Radiotherapy Patients
Gynaecological, Urological or Rectal Cancer
2003-04-01
CompletedPhase II Trial Evaluating Irinotecan and Capecitabine Relapsed/Refractory Upper GI Tumours
Upper Gastrointestinal Tumours
Phase 42003-01-01
CompletedNeoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Su
Oesophageal Carcinoma
Phase 22002-11-01
CompletedPre-operative Epirubicin, Cisplatin, and Capecitabine in Patients With Newly Diagnosed Localised Oesophageal A
Adenocarcinoma of Oesophagus
Phase 22002-11-01
UnknownIH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy
Breast Cancer, Radiation Fibrosis
Phase 22002-09-01
CompletedPhase II Trial Assessing Efficacy and Toxicity of Capecitabine and Oxaliplatin in the Treatment of Colorectal
Colorectal Cancer
Phase 22002-08-01
CompletedA Randomized Trial of Human Growth Hormone (hGH) vs Placebo in Intensively Treated Haemato-Oncology Patients.
Multiple Myeloma, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Phase 2 / Phase 32002-07-01
CompletedAssessing Free Immunoglobulin Light Chains in Patients With Myeloma
Multiple Myeloma
2002-06-01
UnknownDetermination of the Role of Microarray for Prognosis and Prediction to Chemotherapy Sensitivity in Patients W
Oesophageal Cancer
N/A2002-06-01
CompletedA Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and
Locally Advanced Larynx, Hypopharyngeal Squamous Cell Cancers, Locally Advanced Thyroid Cancers
Phase 1 / Phase 22002-01-01
CompletedA Phase II Study of Oxaliplatin Capecitabine and Pre-operative Radiotherapy for Patients With Locally Advanced
Rectal Cancer
Phase 22001-11-01
CompletedA Phase II Trial Comparing the Quality of Life, Tolerability and Toxicity of PEG Intron With INTRON® A in Pati
Multiple Myeloma
Phase 22001-03-01
CompletedA Phase II Trial Evaluating Irinotecan Plus 5FU/LV in Patients With Relapsed/Refractory Upper GI Tumours
Upper Gastrointestinal Tumours
Phase 22000-07-01
UnknownIntensity-Modulated Radiation Therapy in Treating Patients With Prostate Cancer
Prostate Cancer
Phase 12000-03-01
CompletedVitamin E and Pentoxifylline in Treating Women With Lymphedema After Radiation Therapy for Breast Cancer
Breast Cancer, Lymphedema
Phase 22000-01-01
UnknownSentinel Lymph Node Biopsy to Assess Axillary Lymph Nodes in Women With Stage I or Stage II Breast Cancer
Breast Cancer
Phase 21998-12-01
CompletedComparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer
Breast Cancer
Phase 21998-10-01
UnknownDiagnosis and Treatment Planning in Patients Suspected of Having Lung Cancer
Lung Cancer
N/A1998-10-01
UnknownAxillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer
Breast Cancer, Lymphedema, Perioperative/Postoperative Complications
N/A1997-11-01
CompletedSargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer
Head and Neck Cancer, Oral Complications, Radiation Toxicity
Phase 21997-10-01
UnknownEnhanced Ultrasound in Determining Extent of Disease in Women With Primary Breast Cancer
Breast Cancer
N/A1997-08-01
CompletedA Single-arm Phase II Study of Alemtuzumab in Combination With High-dose Methylprednisolone in CLL Patients Wi
Chronic Lymphocytic Leukaemia
Phase 2
UnknownDual Time Point PET Imaging in Lymphoma
Hodgkin's or Non-Hodgkin's Lymphoma
CompletedA Retrospective Review of Gemcitabine, Methylprednisolone Cisplatin (GEM-P) With or Without Rituximab in Patie
Non-Hodgkins Lymphoma
CompletedA Retrospective Study of Toxicity and Outcome of High Dose Chemotherapy With Autologous Stem Cell Transplant i
Non-Hodgkins Lymphoma
CompletedA Retrospective Study of Toxicity and Outcome of High Dose Chemotherapy With Autologous Stem Cell Transplant i
Hodgkin Lymphoma
UnknownA Multicenter, Open-Label Continuation Trial Evaluating the Tolerability and Activity of Depsipeptide (FK228)
Peripheral T Cell Lymphoma (PTCL)
Phase 2