Trials / Unknown
UnknownNCT01037049
Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks
Is Greater Downstaging and Tumour Regression Observed When Surgery is Delayed to 12 Weeks After Completion of Chemoradiotherapy vs 6 Weeks?
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 237 (actual)
- Sponsor
- Royal Marsden NHS Foundation Trust · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to determine whether greater rectal cancer downstaging and regression occurs when surgery is delayed to 12 weeks after completion of radiotherapy/chemotherapy compared to 6 weeks. Hypothesis: Greater downstaging and tumour regression is observed when surgery is delayed to 12 weeks after completion of CRT compared to 6 weeks.
Conditions
- Adenocarcinoma of the Rectum
- Adenocarcinoma
- Adenocarcinoma, Mucinous
- Carcinoma
- Neoplasms, Glandular and Epithelial
- Neoplasms by Histologic Type
- Neoplasms
- Neoplasms, Cystic, Mucinous, and Serous
- Colorectal Neoplasms
- Intestinal Neoplasms
- Gastrointestinal Neoplasms
- Digestive System Neoplasms
- Neoplasms by Site
- Digestive System Diseases
- Gastrointestinal Diseases
- Intestinal Diseases
- Rectal Diseases
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Patients who have surgery at 12 weeks after radiotherapy/chemoradiotherapy |
Timeline
- Start date
- 2009-10-16
- Primary completion
- 2014-12-08
- Completion
- 2019-12-08
- First posted
- 2009-12-21
- Last updated
- 2018-09-17
Locations
23 sites across 4 countries: Brazil, Canada, Cyprus, United Kingdom
Source: ClinicalTrials.gov record NCT01037049. Inclusion in this directory is not an endorsement.