NCT04574063

PIONEER Study of Lifestyle Intervention to Reduced Breast Cancer Risk

Pilot of Lifestyle InterventiON to reducE brEast Cancer RiSk (PIONEER)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Royal Marsden NHS Foundation Trust · Academic / Other
• Sex: Female
• Age: 30 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

A randomised controlled trial in which women discharged from the symptomatic breast clinic, who are above population risk (according to Tyrer Cuzick) will be asked to create lifestyle related goals. They will be told their estimated risk of developing breast cancer and will be randomised to one of three interventions: * Breast cancer risk leaflet only * lifestyle website * lifestyle website plus group coaching. Fifty per cent of women will also be randomised to have Single Nucleotide Polymorphisms (SNPs) performed, and these will be incorporated into their risk score. The primary end point will be whether or not women achieve their lifestyle goal.

Conditions

• Breast Cancer
• Lifestyle Risk Reduction

Interventions

Type	Name	Description
BEHAVIORAL	Lifestyle intervention to reduce breast cancer risk	Women will be educated about lifestyle factors which increase breast cancer risk. They will also be guided through an online goal setting process.

Timeline

• Start date: 2020-09-16
• Primary completion: 2023-12-01
• Completion: 2023-12-01
• First posted: 2020-10-05
• Last updated: 2023-01-18

Locations

1 site across 1 country: United Kingdom