NCT00568087

N-acetylcysteine in Alcohol Dependence

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Minneapolis Veterans Affairs Medical Center · Federal
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The present study is designed to find out if N-acetylcysteine works in reducing alcohol drinking and craving.

Detailed description

The 2 groups (placebo and N-acetylcysteine) will be compared in a double-blind, placebo-controlled trial. The total study duration is 9 weeks which includes a 1-week screening period and an 8-week randomized study drug treatment period.

Conditions

• Alcoholism

Interventions

Type	Name	Description
DRUG	N-acetylcysteine	Patients will take oral N-acetylcysteine 900 mg/day for 1 week, 1800 mg/day for 1 week, 2700 mg/day for 1 week, and then 3600 mg/day.
DRUG	Placebo	Patients will take oral placebo (identical matching placebo) during the study period.

Timeline

• Start date: 2007-12-01
• Primary completion: 2009-08-01
• Completion: 2009-08-01
• First posted: 2007-12-05
• Last updated: 2020-03-18
• Results posted: 2013-11-01

Locations

1 site across 1 country: United States