Clinical Trials Directory

Trials / Sponsors / Otsuka Pharmaceutical Development & Commercialization, Inc.

Otsuka Pharmaceutical Development & Commercialization, Inc.

Industry · 268 registered clinical trials14 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingA Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001
X-linked Congenital Nephrogenic Diabetes Insipidus
Phase 12026-06-02
RecruitingA Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepi
Healthy Volunteers
Phase 12026-03-31
Not Yet RecruitingA Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults
Schizophrenia
Phase 12026-03-20
RecruitingA Trial to Assess How Centanafadine Interacts With Stimulants in the Body
ADHD
Phase 12026-02-05
RecruitingA Brain Imaging Study to Assess the Binding of MSP-2020 to Serotonin 5-HT2A Receptors in Healthy Male Adults
Incomplete Response - Major Depressive Disorder (IR-MDD)
Phase 12026-01-15
RecruitingA Study to Evaluate the Safety and Efficacy of JNT-517 in Participants With Phenylketonuria (PKU)
Phenylketonuria
Phase 32025-10-20
RecruitingA Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis
Pulmonary Tuberculosis
Phase 32025-10-16
RecruitingA Phase 2 Study of JNT-517 in Adolescent Participants With Phenylketonuria
Phenylketonuria (PKU)
Phase 22025-07-16
Not Yet RecruitingA Study to Evaluate the Long-Term Safety and Efficacy of JNT-517 in Participants With Phenylketonuria
Phenylketonuria (PKU)
Phase 32025-06-01
WithdrawnA Proof-of-concept Trial for OPC 131461 in Patients Hospitalized for Worsening Heart Failure
Heart Failure
Phase 22025-04-30
Active Not RecruitingA Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With
Sjogren Disease
Phase 22025-04-23
Active Not RecruitingP3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety
ADHD, Anxiety, Generalized Anxiety
Phase 32025-03-26
RecruitingA Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity o
Systemic Lupus Erythematosus (SLE), Alopecia Areata (AA), Immune-mediated Focal Segmental Glomerulosclerosis (FSGS)
Phase 12025-03-17
CompletedA Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women
Schizophrenia
Phase 12025-03-07
RecruitingA Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With Schizophrenia
Schizophrenia
Phase 32025-02-28
RecruitingTrial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue
IgA Nephropathy
Phase 22024-11-19
CompletedA Trial to Characterize Differences in Blood Levels of Different Lots of Centanafadine QD XR and to Understand
Attention Deficit Disorder With Hyperactivity
Phase 12024-08-29
CompletedA Study to Detect Radioactivity of [14C]-OPC-167832 in Urine and Feces in Healthy Men
Healthy Volunteers
Phase 12023-11-20
CompletedA Study to Investigate the Safety and Tolerability of CAN10 Antibody in Healthy Subjects and in Subjects With
Healthy, Plaque Psoriasis
Phase 12023-08-21
CompletedA Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion
Mental Disorder, Schizophrenia, Major Depressive Disorder
N/A2023-06-26
CompletedA Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With Schizophrenia
Schizophrenia
Phase 12023-06-21
CompletedAn Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-3638
Schizophrenia
Phase 32023-03-31
CompletedA Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anx
Generalized Anxiety Disorder
Phase 2 / Phase 32023-03-08
CompletedTrial to Demonstrate the Equivalence of Two Different Strengths of Oral Centanafadine Capsules in Healthy Subj
Healthy Adult Participants
Phase 12023-03-08
RecruitingA Study to See Iftolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years
Autosomal Recessive Polycystic Kidney (ARPKD)
Phase 32023-01-23
CompletedA Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia
Schizophrenia
Phase 32022-12-19
CompletedA Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Bod
Schizophrenia
Phase 12022-11-15
CompletedA Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder
Major Depressive Disorder
Phase 22022-11-09
Active Not RecruitingFirst-in-Human, Multiple Part Clinical Study of JNT-517 in Healthy Participants and in Participants With Pheny
Phenylketonuria
Phase 1 / Phase 22022-10-31
CompletedA Trial to Compare the Amount of Centanafadine That Enters the Bloodstream for Two Different Formulations of C
Healthy Volunteers
Phase 12022-10-27
CompletedTrial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressiv
Major Depressive Disorder
Phase 22022-09-12
TerminatedA Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Se
Post-traumatic Stress Disorder (PTSD)
Phase 12022-09-07
CompletedA Clinical Study That Will Assess the Effect of SEP-363856 and Prior Antipsychotic (PA) Standard of Care on Gl
Schizophrenia
Phase 12022-08-30
WithdrawnOpen-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety
Major Depressive Disorder (MDD)
Phase 42022-08-29
CompletedA Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)
Attention Deficit/Hyperactivity Disorder
Phase 32022-07-11
WithdrawnA Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less T
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Phase 32022-07-01
CompletedA Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subje
Schizophrenia
Phase 12022-06-13
CompletedA Study to Evaluate the Safety, PK and PD of VIS171 in Participants (Healthy and With Autoimmune Disease)
Autoimmune Diseases
Phase 12022-04-28
CompletedSafety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants Wit
Pulmonary TB
Phase 22022-04-12
Enrolling By InvitationPhase 2/3 Open-Label Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy
Immunoglobulin A Nephropathy
Phase 2 / Phase 32022-04-05
Active Not RecruitingTrial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)
Immunoglobulin A Nephropathy
Phase 32022-03-15
Active Not RecruitingA Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Dis
Attention Deficit/Hyperactivity Disorder
Phase 32022-02-24
CompletedA Trial of Centanafadine Efficacy and Safety in Adolescents With Attention- Deficit/Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder
Phase 32022-02-02
CompletedA Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder
Binge-Eating Disorder
Phase 22021-12-22
CompletedEfficacy of Centanafadine SR as a Potential Smoking Cessation Treatment
Smoking Cessation
Phase 22021-09-15
CompletedA Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the
Schizophrenia
Phase 12021-05-12
CompletedBrexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder
Major Depressive Disorder
Phase 42021-04-01
CompletedA Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine Capsules in Pediatric Subjec
Attention-deficit Hyperactivity Disorder
Phase 12021-03-09
CompletedTrial to Evaluate the Effectiveness of a Digital Therapeutics in Adults Diagnosed With Major Depressive Disord
Major Depressive Disorder
N/A2021-02-25
TerminatedStudy to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients W
Agitation in Patients With Dementia of the Alzheimer's Type
Phase 32020-09-11
TerminatedAssessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients Wit
Agitation in Patients With Dementia of the Alzheimer's Type
Phase 32020-07-13
CompletedA Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults
Schizophrenia
Phase 12020-06-18
CompletedA Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine in Pediatric Subjects With A
Attention Deficit Hyperactivity Disorder
Phase 12020-06-11
TerminatedEfficacy and Safety of Oral OPS-2071 in Participants With Crohn's Disease Showing Symptoms of Active Inflammat
Crohn's Disease
Phase 22020-02-25
CompletedA Single-blind, Placebo-controlled, Outpatient Trial to Assess the Effects of Single Oral Tablet Dose of OPC-2
Epilepsy
Phase 12020-02-18
CompletedBrexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disor
Irritability Associated With Autism Spectrum Disorder
Phase 32020-01-23
CompletedEvaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality
Borderline Personality Disorder
Phase 2 / Phase 32020-01-13
CompletedA Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.
Schizophrenia
Phase 32019-11-21
TerminatedA Clinical Study to Evaluate the Long-term Safety and Tolerability of an Investigational Drug in People With S
Schizophrenia
Phase 32019-11-20
CompletedBrexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disor
Irritability Associated With Autism Spectrum Disorder (ASD)
Phase 32019-10-30
CompletedBrexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Dis
Post Traumatic Stress Disorder
Phase 32019-10-30
CompletedA Trial of Brexpiprazole in the Treatment of Borderline Personality Disorder
Borderline Personality Disorder
Phase 22019-10-17
CompletedBrexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD
Post Traumatic Stress Disorder
Phase 32019-10-17
CompletedOpen-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Ped
Attention Deficit Hyperactivity Disorder
Phase 22019-10-07
CompletedA Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic Peopl
Schizophrenia
Phase 32019-09-30
CompletedA Clinical Trial to Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With
Schizophrenia
Phase 32019-09-11
CompletedA Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychot
Schizophrenia
Phase 12019-08-07
CompletedA Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder
Schizophrenia, Bipolar I Disorder
Phase 1 / Phase 22019-08-01
TerminatedA Trial in Adult Participants With Schizophrenia Treated Prospectively for 6-months With Abilify MyCite®
Schizophrenia
Phase 32019-04-29
CompletedTrial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar D
Bipolar Disorder, Schizophrenia
Phase 12019-03-27
TerminatedEfficacy, Safety, and Tolerability of AVP-786 for the Treatment of Negative Symptoms of Schizophrenia
Schizophrenia
Phase 2 / Phase 32019-02-15
CompletedA Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
Phase 32019-02-14
CompletedA Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disord
Schizophrenia, Bipolar I Disorder
Phase 12019-01-31
CompletedA Trial Evaluating the Efficacy, Safety, & Tolerability of Centanafadine Sustained-release Tablets in Adults W
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
Phase 32019-01-16
CompletedA Trial to Evaluate the Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adult
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
Phase 32019-01-16
CompletedA Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis
Pulmonary TB
Phase 1 / Phase 22018-10-18
TerminatedTrial to Evaluate the Long-term Efficacy of Oral Aripiprazole in the Treatment of Pediatric Participants With
Tourette's Disorder (TD)
Phase 42018-10-13
CompletedA 12-week Extension Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subject
Alzheimer's Disease
Phase 32018-10-11
CompletedA Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adult
Major Depressive Disorder
Phase 32018-07-13
TerminatedA Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite
Schizophrenia, Bipolar 1 Disorder, Major Depressive Disorder
Phase 42018-06-28
CompletedA Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals
Schizophrenia, Schizoaffective Disorder, First Episode Psychosis
Phase 42018-05-21
CompletedA Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated W
Agitation Associated With Alzheimer's Dementia, Alzheimer Dementia
Phase 32018-05-16
TerminatedStudy to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive
Intermittent Explosive Disorder
Phase 22018-01-18
CompletedThe Safety and Efficacy of OPC-64005 in the Treatment of Adult Attention-deficit/Hyperactivity Disorder
Adult Attention Deficit Hyperactivity Disorder
Phase 22017-11-09
CompletedA Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar
Bipolar I Disorder, Acute Mania
Phase 32017-10-24
CompletedAssessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quin
Agitation in Patients With Dementia of the Alzheimer's Type
Phase 32017-10-13
CompletedTrial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years O
ADHD, Autism, Bipolar I Disorder
Phase 12017-10-10
CompletedA Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes, Associated With Bipo
Bipolar I Disorder, Manic Episode
Phase 32017-09-19
CompletedA Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipol
Bipolar I Disorder, Manic Episode
Phase 32017-09-14
CompletedSafety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With
Schizophrenia
Phase 32017-08-23
CompletedTrial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescent
Schizophrenia
Phase 32017-06-30
CompletedStudy to Determine the Pharmacokinetics, Safety & Tolerability of Aripiprazole in Adults With Schizophrenia
Schizophrenia
Phase 12017-06-14
CompletedStudy to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhi
Neurobehavioral Disinhibition
Phase 22017-05-30
CompletedAn Extension Study of Safety and Tolerability of SEP-363856 in Adult Subjects With Schizophrenia
Schizophrenia
Phase 22017-01-31
CompletedA Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With P
Stress Disorders, Post-Traumatic
Phase 22017-01-26
TerminatedSafety and Tolerability Study of Single-dose Administration of Brexpiprazole in Adult Subjects With Schizophre
Schizophrenia
Phase 12017-01-01
CompletedA Study to Evaluate the Efficacy, Safety and Tolerability of SEP-363856 in Subjects With Parkinson's Disease P
Parkinson Disease Psychosis
Phase 22016-12-31
CompletedA Study to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic Adults With Schizophrenia
Schizophrenia
Phase 22016-12-05
CompletedSafety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autos
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Phase 32016-09-23
TerminatedAn Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euv
Hyponatremia
Phase 32016-04-22
CompletedExploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System
Schizophrenia, Major Depressive Disorder, Bipolar I Disorder
Phase 22016-03-01
TerminatedA Phase 1 Study to Investigate the Safety, Tolerance, Food Effect, Pharmacokinetics and Pharmacodynamics of Si
Adult Attention-deficit Hyperactivity Disorder (ADHD)
Phase 12015-12-01
TerminatedLong Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients Wi
Agitation in Patients With Dementia of the Alzheimer's Type
Phase 32015-11-13
CompletedEfficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Participants With Dementia of
Agitation in Participants With Dementia of the Alzheimer's Type
Phase 32015-11-11
WithdrawnA Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic Hyponatremia
Hyponatremia
Phase 32015-11-01
TerminatedStudy of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hyp
Hyponatremia
Phase 32015-09-22
CompletedSafety and Efficacy Study of Centanafadine Sustained-Release (CTN SR) in Adults With Attention-Deficit Hyperac
Attention Deficit Disorder With Hyperactivity
Phase 22015-08-03
CompletedEfficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the A
Agitation in Patients With Dementia of the Alzheimer's Type
Phase 32015-07-23
CompletedStudy to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescent
Schizophrenia
Phase 12015-03-01
CompletedMonotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Schizophrenia With Impulsivity
Schizophrenia With Impulsivity
Phase 32015-02-01
CompletedSubstudy 'B' of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (
Device Latency
Phase 42015-02-01
CompletedLong Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease
Polycystic Kidney, Autosomal Dominant
Phase 32014-10-17
WithdrawnBrexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and Irritability
Major Depressive Disorder and Irritability
Phase 32014-09-01
CompletedOpen-label Study to Assess Usability of the Medical Information Device #1 (MIND1) System in Adults With Schizo
Schizophrenia, Mental Disorder, Nervous System Diseases
Phase 22014-08-01
CompletedStudy of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatmen
Depressive Disorder, Depression, Depressive Disorder, Major
Phase 32014-07-01
CompletedA Study to Evaluate the Effectiveness and Safety of Topical OPA-15406 Ointment to Treat Participants With Atop
Atopic Dermatitis
Phase 22014-06-20
CompletedThis is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in Peopl
Narcolepsy
Phase 12014-06-05
CompletedSafety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previo
Agitation Associated With Alzheimer's Disease, Alzheimer's Type, Mental Disorder
2014-06-01
CompletedEfficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4
Chronic Kidney Disease, Autosomal Dominant Polycystic Kidney Disease
Phase 32014-05-01
CompletedA Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users
Healthy Volunteers, Drug Users
Phase 12014-05-01
CompletedSubstudy of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND
Device Latency
Phase 42014-03-21
CompletedStudy Assessing SEP-363856 in Male and Female Volunteers With High or Low Schizotype Characteristics
Schizophrenia
Phase 12014-03-01
WithdrawnAdherence to Treatment, Safety and Tolerability Study of the Medical Information Device #1 (MIND1) in Subjects
Bipolar 1 Disorder, Schizophrenia, Mental Disorder
Phase 22014-03-01
CompletedBrexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia
Schizophrenia
Phase 32014-02-01
CompletedA Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy
Drug-drug Interaction
Phase 12014-01-01
CompletedOpen-Label Observational Pilot Study to Evaluate the Pharmacokinetics of Aripiprazole in Subjects With Bipolar
Bipolar 1 Disorder, Schizophrenia, Mental Disorder
2013-12-01
CompletedMonotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Early-Episode Schizophrenia
Schizophrenia
Phase 32013-11-01
CompletedBrexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressi
MDD
Phase 32013-11-01
CompletedBrexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symp
Major Depressive Disorder, Anxiety
Phase 32013-11-01
CompletedBrexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adju
Major Depressive Disorder (MDD)
Phase 32013-11-01
CompletedA PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
Phase 1 / Phase 22013-11-01
CompletedStudy of Flexible Doses of the Triple Reuptake Inhibitor EB-1020 Sustained Release (SR) in the Treatment of Ad
Adult ADHD
Phase 22013-10-03
CompletedStudy Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With
Schizophrenia
Phase 12013-10-01
CompletedPET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With Schizophrenia
Schizophrenia
Phase 12013-09-01
CompletedSafety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation
Agitation Associated With, Alzheimer's Disease, Alzheimer's Type
Phase 32013-09-01
CompletedA Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects Wit
Schizophrenia
Phase 12013-08-01
CompletedA 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidr
Multidrug Resistant Tuberculosis
Phase 22013-07-20
CompletedA Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy,
Agitation Associated With, Alzheimer's Disease, Alzheimer's Type
Phase 32013-07-11
CompletedSafety and Tolerability Study of Aripiprazole IM Depot in Adult Subjects With Schizophrenia
Schizophrenia, Mental Disorder, Nervous System Diseases
Phase 12013-07-01
CompletedPharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resis
Multidrug Resistant Tuberculosis, Pediatric
Phase 12013-06-14
CompletedA Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation
Normal, Healthy Volunteers
Phase 12013-02-01
CompletedOpen-label, Extension Study of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in Patients With Schiz
Schizophrenia
Phase 32013-01-01
CompletedSafety and Tolerability of Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
Tourette's Disorder, Tic Disorder
Phase 32013-01-01
CompletedA Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive
Depressive Disorder, Depression, Depressive Disorder, Major
Phase 32012-12-01
CompletedOpen-label Study to Evaluate the Effectiveness of an Intramuscular Formulation of Aripiprazole (OPC-14597) as
Bipolar I
Phase 32012-11-01
CompletedStudy Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescent
Tourette's Disorder, Tic Disorder
Phase 32012-11-01
CompletedTrial of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in the Acute Treatment of Adults With Schizo
Schizophrenia
Phase 32012-10-01
CompletedEfficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults With Schizo
Acute Schizophrenia
Phase 32012-10-01
CompletedA Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermati
Atopic Dermatitis
Phase 12012-08-01
CompletedEfficacy, Safety, and Tolerability of an Intramuscular Formulation of Aripiprazole (OPC-14597) as Maintenance
Bipolar I Disorder
Phase 32012-08-01
CompletedPhase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects Wit
Major Depressive Disorder
Phase 12012-07-01
CompletedA Phase 1, Open-label, Multiple Dose Escalation Trial to Determine Safety and Tolerability of Once Daily OPB-1
Solid Tumors
Phase 12012-06-01
CompletedAn Open Label Study of Aripiprazole Intramuscular Injection in Subjects With Schizophrenia
Schizophrenia
Phase 12012-05-01
CompletedSafety and Tolerability Trial of Aripiprazole IM Depot Treatment in Adult Subjects With Schizophrenia Stabiliz
Schizophrenia
Phase 12012-01-01
TerminatedOpen-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics V
Schizophrenia
Phase 32012-01-01
TerminatedAscending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fib
Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Phase 12011-11-01
CompletedSafety and Tolerability Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Dis
Tourette's Disorder
Phase 32011-10-19
CompletedSafety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the
Depressive Disorder, Depression, Depressive Disorder, Major
Phase 32011-10-01
Completed8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Autosomal Dominant Polycystic Kidney Disease
Phase 22011-10-01
CompletedSafety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis
Multidrug-resistant Tuberculosis
Phase 32011-09-02
CompletedOpen-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics V
Schizophrenia
Phase 32011-09-01
CompletedSafety and Tolerability Study of Oral OPC-34712 as Maintenance Treatment in Adults With Schizophrenia
Schizophrenia
Phase 32011-09-01
CompletedEfficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
Tourette's Disorder
Phase 32011-08-02
CompletedEfficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
Tourette's Disorder
Phase 32011-07-27
CompletedStudy of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With
Depressive Disorder, Depression, Depressive Disorder, Major
Phase 32011-07-01
CompletedStudy of the Effectiveness of Three Different Doses of OPC-34712 in the Treatment of Adults With Acute Schizop
Acute Schizophrenia
Phase 32011-07-01
CompletedEfficacy & Safety Study of Oral Aripiprazole in Adolescents With Schizophrenia
Schizophrenia
Phase 32011-07-01
CompletedTrial to Evaluate the Effects of OPC-34712 on QT/QTc in Subjects With Schizophrenia or Schizoaffective Disorde
Schizophrenia, Schizoaffective Disorder
Phase 12011-07-01
CompletedEfficacy Study of OPC-34712 in Adults With Acute Schizophrenia
Acute Schizophrenia
Phase 32011-07-01
CompletedObservational Study in Patients With Autosomal Dominant Polycystic Kidney Disease
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
2011-06-01
CompletedStudy of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adu
Depressive Disorder, Depression, Depressive Disorder, Major
Phase 32011-06-01
CompletedDasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic Cancer
Pancreatic Cancer
Phase 22011-06-01
CompletedRetrospective Database Study of Real World Abilify Outcomes in Major Depressive Disorder (MDD)
Depressive Disorder, Major
2011-01-01
CompletedTrial Evaluating OPC-34712 in Subjects With Normal Renal Function and Renally Impaired Subjects
Schizophrenia, Psychiatric Disorders
Phase 12011-01-01
CompletedA Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired Subjects
Schizophrenia
Phase 12010-12-01
TerminatedTo Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants
Major Depressive Disorder (MDD)
Phase 32010-11-18
TerminatedStudy to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera
Major Depressive Disorder (MDD)
Phase 32010-10-04
TerminatedEffects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia
Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
Phase 32010-10-01
CompletedShort-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Diseas
Autosomal Dominant Polycystic Kidney Disease
Phase 22010-10-01
CompletedDose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD
Autosomal Dominant Polycystic Kidney Disease
Phase 22010-10-01
TerminatedStudy to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera
Major Depressive Disorder (MDD)
Phase 32010-07-29
TerminatedStudy to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Thera
Major Depressive Disorder (MDD)
Phase 32010-07-13
TerminatedSafety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bip
Adolescent Schizophrenia, Child or Adolescent Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features
Phase 32010-07-01
CompletedAn Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Participants With
Schizophrenia
Phase 32010-06-24
CompletedTolvaptan Extension Study in Participants With ADPKD
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Phase 32010-05-26
CompletedIV Busulfan Plus Bortezomib Conditioning Regimen for Second Autologous Stem Cell Transplant in Multiple Myelom
Multiple Myeloma
Phase 22010-05-01
CompletedStudy of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention D
Attention Deficit Hyperactivity Disorder
Phase 22010-03-16
CompletedStudy of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depr
Major Depressive Disorder
Phase 22010-03-01
TerminatedSafety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosis
Tuberculosis
Phase 22010-02-19
CompletedPhase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer
Advanced Cancer
Phase 12010-02-01
CompletedPK-directed Dose Adjustment of IV Busulfan Conditioning Regimen for Autologous Stem Cell Transplant in Lymphom
Lymphoma
Phase 22010-01-01
CompletedStudy of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major De
Major Depressive Disorder
Phase 22009-09-01
CompletedMulticenter, Open-label, Safety and Tolerability Study
Schizophrenia
Phase 22009-08-01
CompletedStudy to Evaluate the Efficacy, Safety, and Tolerability of Oral OPC-34712 and Aripiprazole for Treatment of A
Schizophrenia
Phase 22009-07-01
CompletedThe Effect of Patient Cost-Sharing on Antidepressant and Adjunctive Therapy Use
Depressive Disorder, Major
2009-06-01
CompletedStudy of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major De
Major Depressive Disorder
Phase 22009-05-01
CompletedOutcomes in MEasurement-Based Treatment
Depressive Disorder, Major
2009-05-01
TerminatedTrial Comparing the Effects of Aripiprazole With Those of Standard of Care on Non-HDL Cholesterol in Patients
Schizophrenia, Schizoaffective Disorder, Bipolar I Disorder
Phase 32009-04-01
CompletedA Trial to Evaluate Safety, Tolerability, and Efficacy of Orally Administered OPC-67683
Tuberculosis, Multidrug-Resistant
Phase 22009-03-26
TerminatedPilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema
Chronic Obstructive Pulmonary Disease
Phase 22009-03-01
CompletedIntramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia
Schizophrenia
Phase 32008-12-01
CompletedPositron Emission Tomagraphy (PET) Study Following a Single Oral Dose of OPC-34712
Schizophrenia
Phase 12008-12-01
CompletedIntramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia
Schizophrenia
Phase 32008-09-01
CompletedIntramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia
Schizophrenia
Phase 32008-07-01
CompletedStudy to Evaluate the Efficacy and Safety of Aripiprazole Administered With Lithium or Valproate Over 12 Weeks
Bipolar Disorder Mania
Phase 32008-06-01
CompletedA Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tube
Tuberculosis, Pulmonary, Tuberculosis, Multidrug Resistant, Extensively Drug-Resistant Tuberculosis
Phase 22008-05-08
CompletedA Multiple Dose Safety, Tolerability and Pharmacokinetics Study in Adult Patients With Schizophrenia Following
Schizophrenia
Phase 12007-11-01
CompletedImpact of Atypical Antipsychotic Therapy on Health Outcomes and Costs Among Patients With Major Depressive Dis
Depressive Disorder, Major
2007-10-01
CompletedEffects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly
Hyponatremia
Phase 32007-08-01
CompletedTolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Polycystic Kidney Disease, Autosomal Dominant
Phase 32007-01-01
WithdrawnA Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode
Bipolar Disorder
Phase 32006-12-01
CompletedStudy of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autisti
Autistic Disorder, Behavioral Symptoms
Phase 32006-09-01
CompletedAripiprazole and Lexapro Drug Interaction Study
Healthy
Phase 12006-08-01
CompletedAripiprazole and Effexor XR Drug Interaction Study
Healthy
Phase 12006-08-01
CompletedDrug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder
Bipolar Disorder
Phase 12006-07-01
CompletedAripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaff
Schizophrenia, Schizoaffective Disorder
Phase 42006-07-01
CompletedStudy of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
Behavioral Symptoms, Autistic Disorder
Phase 32006-06-01
CompletedStudy of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
Autistic Disorder
Phase 32006-06-01
CompletedOral Aripiprazole Open-Label Rollover Study
Schizophrenia
Phase 32006-04-01
CompletedA Study of Adjunctive Treatment of Aripiprazole in Schizophrenic Patients
Schizophrenia
Phase 42005-12-01
CompletedA Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term M
Bipolar Disorder
Phase 42005-12-01
CompletedTolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Di
Polycystic Kidney, Autosomal Dominant
Phase 22005-12-01
CompletedA Study of Aripiprazole (Abilify) in Patients With Bipolar Mania
Bipolar Disorder
Phase 42005-09-01
CompletedA Switch Study of BMS-337039 in Schizophrenic Out-patients
Schizophrenia
Phase 42005-06-01
CompletedEffect on Cognitive Function of a Treatment With Aripiprazole
Schizophrenia
Phase 42005-03-01
CompletedA Study of Aripiprazole in Patients With Major Depressive Disorder
Major Depressive Disorder
Phase 32005-03-01
CompletedAripiprazole in Children and Adolescents With Bipolar I Disorder
Bipolar Disorder
Phase 32005-03-01
CompletedA Study of Aripiprazole in Patients With Schizophrenia in General Psychiatric Practices
Schizophrenia and Schizoaffective Disorder
Phase 32005-03-01
CompletedHeart Pressure Assessment Study With Tolvaptan to Treat Congestive Heart Failure
Heart Failure, Congestive
Phase 22004-12-01
CompletedStudy of Aripiprazole in Patients With Acute Bipolar Mania
Bipolar Disorder
Phase 32004-12-01
CompletedStudy of Aripiprazole in Patients With Bipolar I Disorder
Bipolar Disorder
Phase 32004-10-01
CompletedA Long-Term Study of Aripiprazole in Patients With Major Depressive Disorder
Major Depressive Disorder
Phase 32004-09-01
CompletedAripiprazole Open-Label, Safety and Tolerability Study
Schizophrenia, Bipolar Disorder
Phase 32004-09-01
CompletedSchizophrenia Trial of Aripiprazole
Schizophrenia
Phase 32004-07-01
CompletedAripiprazole in Adolescents With Schizophrenia
Schizophrenia
Phase 32004-07-01
CompletedAripiprazole Pharmacokinetics (PK) and Tolerability Study in Children and Adolescents
Schizophrenia, Mania
Phase 22004-07-01
CompletedAripiprazole in Patients With Acute Mania
Bipolar Disorder
Phase 32004-06-01
CompletedA Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode
Bipolar I Disorder
Phase 32004-06-01
CompletedCORE: A Study of OPC-6535 With Asacol® in Maintaining Ulcerative Colitis (UC) Remission
Ulcerative Colitis
Phase 32004-05-01
CompletedInternational, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Pa
Hyponatremia
Phase 32004-05-01
CompletedStudy of Rebamipide Eye Drops to Treat Dry Eye
Keratoconjunctivitis Sicca
Phase 32004-05-01
CompletedStudy of Rebamipide Eye Drops to Treat Dry Eye
Keratoconjunctivitis Sicca
Phase 32004-05-01
CompletedStudy of Aripiprazole in Subjects With Alcoholism
Alcoholism
Phase 42004-04-01
CompletedEffects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Di
Body Weight Change, Schizophrenia, Schizoaffective Disorder
Phase 32004-03-01
CompletedAripiprazole Oral Acceptability Trial
Schizophrenia
Phase 32004-03-01
CompletedStudy of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode
Bipolar Disorder
Phase 32004-01-01
CompletedIntramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
Dementia, Alzheimer's Disease
Phase 32003-12-01
Completed"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
Hyponatremia, Water Intoxication, Inappropriate ADH Syndrome
Phase 32003-11-01
CompletedStudy of Three Doses of Aripiprazole in Patients With Acute Schizophrenia
Schizophrenia
Phase 42003-11-01
CompletedEVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
Congestive Heart Failure
Phase 32003-09-01
CompletedAripiprazole in Patients With Psychosis Associated With Parkinson's Disease
Parkinson's Disease, Psychoses
Phase 42003-07-01
CompletedFACTS I: A Study to Test the Safety and Effectiveness of a New Medication on the Treatment of Active Ulcerativ
Ulcerative Colitis
Phase 32003-05-01
CompletedFACTS II: A Study to Test the Safety and Effectiveness of a New Medication on the Treatment of Active Ulcerati
Ulcerative Colitis
Phase 32003-05-01
Completed"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
Hyponatremias, Water Intoxication, Inappropriate ADH Syndrome
Phase 32003-04-01
CompletedAripiprazole for Schizophrenia Outpatients Completing BMS Clinical Trials
Schizophrenia
Phase 32003-03-01
CompletedA Study of Aripiprazole in the Management of Patients With Schizophrenia in the General Psychiatric Practices
Schizophrenia
Phase 32002-09-01
CompletedMulticenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left
Congestive Heart Failure
Phase 22002-07-01
CompletedBroad Effectiveness: Study With Aripiprazole
Schizophrenia, Schizoaffective Disorder
Phase 32002-07-01
CompletedStudy of Aripiprazole in the Treatment of Patients With Acute Symptoms of Bipolar Disorder
Bipolar I Disorder
Phase 32002-06-01
CompletedStudy to Compare the Effects of Two Dosages of Tolvaptan in Congestive Heart Failure Patients
Congestive Heart Failure
Phase 22002-05-01
CompletedStudy of Alternate Formulation of Aripiprazole in Agitated Patients With Schizophrenic Disorders
Schizophrenia
Phase 2 / Phase 32002-04-01
CompletedStudy of Aripiprazole in the Treatment of Patients With Acute Symptoms in Bipolar Disorder
Bipolar Disorder
Phase 32002-02-01
CompletedAripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of Alzheimer's Type
Dementia, Alzheimer Type
Phase 32000-08-01
CompletedComparative Study of Aripiprazole and Olanzapine in the Treatment of Patients With Acute Schizophrenia
Schizophrenia
Phase 32000-06-01
CompletedStudy of Aripiprazole in Patients With a History of Bipolar Disorder
Bipolar Disorder
Phase 32000-03-01
CompletedStudy of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's
Alzheimer Disease
Phase 32000-03-01
CompletedStudy of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's
Alzheimer Disease
Phase 32000-01-01
TerminatedA Follow-on Study of the Long-Term Safety of Aripiprazole in Patients With Chronic Schizophrenia
Schizophrenia
Phase 31998-04-01