NCT00071331

EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan

Protocol 156-03-236: Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long Term Efficacy and Safety of Oral Tolvaptan Tablets in Subjects Hospitalized With Worsening Congestive Heart Failure

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 3,600 (planned)
• Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF).

Detailed description

Study Design: Multicenter, randomized, double-blind, placebo-controlled

Conditions

• Congestive Heart Failure

Interventions

Type	Name	Description
DRUG	Tolvaptan

Timeline

• Start date: 2003-09-01
• Primary completion: 2006-07-01
• Completion: 2006-07-01
• First posted: 2003-10-21
• Last updated: 2012-05-03

Locations

378 sites across 18 countries: United States, Argentina, Belgium, Brazil, Canada, Czechia, France, Germany, Italy, Netherlands, Norway, Poland, Romania, Russia, Spain, Sweden, Switzerland, United Kingdom