Clinical Trials Directory

Trials / Terminated

TerminatedNCT02012959

Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia

A Phase 3b, Multicenter, Open-label, Randomized Withdrawal Trial of the Effects of Titrated Oral SAMSCA ® (Tolvaptan) on Serum Sodium, Pharmacokinetics, and Safety in Children and Adolescent Subjects Hospitalized With Euvolemic or Hypervolemic Hyponatremia

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
9 (actual)
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc. · Industry
Sex
All
Age
4 Weeks – 17 Years
Healthy volunteers
Not accepted

Summary

The purpose of this trial was to demonstrate that tolvaptan effectively and safely increases and maintains serum sodium concentrations in children and adolescent participants with euvolemic or hypervolemic hyponatremia.

Conditions

Interventions

TypeNameDescription
DRUGTolvaptan

Timeline

Start date
2015-09-22
Primary completion
2017-07-24
Completion
2017-07-24
First posted
2013-12-17
Last updated
2018-09-26
Results posted
2018-08-28

Locations

7 sites across 3 countries: United States, Italy, United Kingdom

Source: ClinicalTrials.gov record NCT02012959. Inclusion in this directory is not an endorsement.