NCT00961792

Chicago Social Drinking Project

Individual Differences After Consumption of Alcohol and Other Common Substances and Long-Term Follow-Up of Social Drinking, Young Adults

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 800 (estimated)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study attempts to elucidate the factors that contribute to escalation and maintenance of excessive ethanol drinking in young adults by: 1. Examining subjective and objective response differences to alcohol and other common substances in a sample of adults with varying consumption patterns. 2. Determining whether response to alcohol and other substances is predictive of future consumption patterns through longitudinal follow-up interviews. 3. Examining the relationship between responses to alcohol and other substances at baseline and re-examination testing to evaluate if consumption patterns moderate this relationship.

Conditions

• Alcoholism

Interventions

Type	Name	Description
DRUG	Ethanol	Beverage containing 0.8 g/kg ethanol, 0.4 g/kg ethanol
DRUG	Placebo	Beverage containing 0.0 g/kg alcohol to act as placebo
DRUG	Diphenhydramine	Beverage containing dose equivalent to 1.5 standard doses of Diphenhydramine (Benadryl)
DRUG	Caffeine	Beverage containing the equivalent of 1.5 times the participant's daily caffeine intake

Timeline

• Start date: 2004-03-01
• Primary completion: 2026-09-01
• Completion: 2027-10-01
• First posted: 2009-08-19
• Last updated: 2026-04-09

Locations

1 site across 1 country: United States