NCT04934553

Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression

Amplification of Positivity for Alcohol Use Disorder (AMP-A): Feasibility and Pilot Study

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Charles Taylor · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine the feasibility of a protocol in which individuals with comorbid depression or anxiety disorders and alcohol use disorder will be randomized to complete Amplification of Positivity for Alcohol Use Disorder (AMP-A)- a psychological treatment focused on increasing positive thoughts, emotions, and behaviors- or a traditional cognitive-behavioral therapy (CBT) intervention. Assessed outcomes will include participant acceptability and completion rates, participant compliance with the intervention, positive and negative affect, substance use- and depression and anxiety-related symptom severity, and functional disability.

Conditions

• Alcoholism
• Alcohol Drinking
• Drinking Behavior
• Alcohol-Related Disorders
• Substance-Related Disorders
• Mental Disorder
• Anxiety
• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Amplification of Positivity Training	12 90-minute, clinician-administered treatment sessions focused on presenting rationale and instructions for completing positive activity exercises (e.g., gratitude, acts of kindness) designed to increase positive emotions, cognitions, and behaviors.
BEHAVIORAL	Cognitive-behavioral Therapy	12 90-minute, clinician-administered treatment sessions focused on strategies to alter cognitions and behavior related to alcohol use.

Timeline

• Start date: 2021-05-20
• Primary completion: 2023-01-01
• Completion: 2023-06-01
• First posted: 2021-06-22
• Last updated: 2022-04-20

Locations

2 sites across 1 country: United States