| Not Yet Recruiting | Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE NCT05601206 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Technology dRiven Enhancement to Engage & Connect NCT06910683 | Weill Medical College of Cornell University | N/A |
| Not Yet Recruiting | Community Health Worker Implementation of Transdiagnostic Evidence-based Mental Health Intervention for Spanis NCT07390630 | University of Illinois at Chicago | N/A |
| Not Yet Recruiting | Personalizing Mental Health Treatment for Youth and Families NCT07425366 | University of Oregon | N/A |
| Not Yet Recruiting | Benefits of Exergames on Neurocognitive Functions in Adults Suffering From Depression NCT06536530 | MAP Institute | N/A |
| Recruiting | Treatment of Depression Post-SCI NCT04263285 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms NCT07202325 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Mindfulness in High Risk Pregnancies NCT04496115 | University of Alberta | N/A |
| Not Yet Recruiting | Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) NCT06811454 | Case Comprehensive Cancer Center | N/A |
| Not Yet Recruiting | Multimodal Differences in Effort-based Decision-Making in Depression NCT06648460 | Georgia Institute of Technology | N/A |
| Not Yet Recruiting | Effect of Virtual Reality on Depression in Adolescent Females NCT07452341 | Cairo University | N/A |
| Not Yet Recruiting | Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Be NCT07333014 | College of Management Academic Studies | N/A |
| Not Yet Recruiting | By Youth, For Youth: Digital Supported Peer Navigation for Addressing Child Mental Health Care NCT06122688 | University of California, Riverside | N/A |
| Not Yet Recruiting | Yoga, Meditation and Mindful Eating Intervention in University Students NCT07280078 | Universidad de Antioquia | N/A |
| Not Yet Recruiting | Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV NCT07007221 | University of Minnesota | Phase 2 |
| Not Yet Recruiting | Psychological Burden of Anxiety and Depression Among Future Physicians: A Cross-sectional Study at Assiut Univ NCT07197125 | Assiut University | — |
| Not Yet Recruiting | CommunityRx-Dementia + Peer Navigation (CRxDpeer) NCT07346183 | University of Chicago | N/A |
| Withdrawn | Intervention for Rural Cancer Patients NCT05091593 | University of Pittsburgh | N/A |
| Not Yet Recruiting | The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms NCT06701578 | HealthPartners Institute | N/A |
| Not Yet Recruiting | Cognitive Enhancement in Recurrent Depression (The COG-D-R Study) NCT07527273 | Vanderbilt University Medical Center | N/A |
| Not Yet Recruiting | Comparison of the Efficacy of Transcranial Direct Current Stimulation at Home Versus in Hospital Settings in P NCT07490379 | Nantes University Hospital | N/A |
| Not Yet Recruiting | Sleep and Circadian Interventions for College Students at High Risk of Suicide NCT07346014 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for F NCT07507214 | University of Florida | Phase 2 / Phase 3 |
| Not Yet Recruiting | The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple NCT07504120 | University of Illinois at Chicago | N/A |
| Not Yet Recruiting | Internet-Based Group CBT for Anxiety and Depression Among International Students NCT07365787 | Universiti Putra Malaysia | N/A |
| Not Yet Recruiting | Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 3) NCT07010133 | San Diego State University | N/A |
| Not Yet Recruiting | Co-Designing and Evaluating Additional Mothers and Babies Program Content for Expectant and New Parents of Chi NCT07469176 | Northwestern University | N/A |
| Recruiting | Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid NCT07336238 | University of Washington | Phase 2 |
| Not Yet Recruiting | Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis NCT07503093 | Mclean Hospital | N/A |
| Not Yet Recruiting | A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression NCT07485595 | Tasly Pharmaceutical Group Co., Ltd | Phase 2 / Phase 3 |
| Not Yet Recruiting | Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), F NCT07149428 | National Institute on Deafness and Other Communication Disorders (NIDCD) | — |
| Not Yet Recruiting | Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2) NCT06753123 | San Diego State University | N/A |
| Not Yet Recruiting | Ganoderma Spores Modulate the Gut-Brain Axis NCT07524777 | Ling Zhiqiang | N/A |
| Not Yet Recruiting | Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing NCT07216911 | Trustees of Dartmouth College | N/A |
| Recruiting | Implementing Depression and Adherence Treatment NCT07032363 | University of Miami | N/A |
| Not Yet Recruiting | The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study NCT06206226 | University of Wisconsin, Madison | N/A |
| Not Yet Recruiting | Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors NCT07481903 | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine | N/A |
| Not Yet Recruiting | Mindfulness Training During Accelerated TMS for Depression NCT07369557 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS) NCT07454460 | Milton S. Hershey Medical Center | N/A |
| Not Yet Recruiting | Effect of Reading a Personal Narrative Book on Emotional Regulation in Women of Childbearing Age Undergoing Hy NCT07430488 | Groupe SantéCité SantéCité Enseignement-Recherche-Innovation (GCS SCERI) | N/A |
| Not Yet Recruiting | A Randomized Controlled Trial of a VR Social Music-Movement Exergame for Depression and Anxiety in Young Adult NCT07482852 | Hunan University of Traditional Chinese Medicine | N/A |
| Not Yet Recruiting | Mindfulness Engaged Neurostimulation for Depression (MEND II) NCT07512284 | University of California, San Diego | Phase 2 |
| Not Yet Recruiting | Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments NCT06976840 | Marta Peciña, MD PhD | N/A |
| Not Yet Recruiting | Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression NCT07430774 | University of Texas Southwestern Medical Center | — |
| Not Yet Recruiting | Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico NCT06834893 | Aditi Bunker | N/A |
| Recruiting | A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression NCT06906939 | University of California, Los Angeles | EARLY_Phase 1 |
| Not Yet Recruiting | Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study NCT07250061 | Boston University | N/A |
| Not Yet Recruiting | The WeACT Program for Family Caregivers of People Living With Dementia NCT07342569 | University of South Florida | N/A |
| Withdrawn | Virtual Communication in the Hospital: Impact on Patients and Surrogates NCT05395039 | Indiana University | N/A |
| Recruiting | Sleep Health in U.S. Marines NCT07420205 | San Diego State University | Phase 2 |
| Not Yet Recruiting | Transcranial Direct Current Stimulation for Depression NCT07500064 | The Second Hospital of Anhui Medical University | N/A |
| Not Yet Recruiting | Development and Validation of Psycho-Social Program (PSP) NCT07456410 | Government College University Faisalabad | N/A |
| Not Yet Recruiting | Bonding Before Birth: A mHealth Intervention for First-time Expectant Couples NCT07483515 | Institute for Human Development and Potential (IHDP), Singapore | N/A |
| Recruiting | Group-Based Acceptance and Commitment Therapy Versus Active Control in University Students With Emotional Symp NCT07506148 | Mónica Larrosa Signorelli | N/A |
| Recruiting | ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities i NCT07360600 | University of South Florida | N/A |
| Not Yet Recruiting | Preliminary Testing and Development of a Short Digital Intervention for Patients on Waiting Lists for Psycholo NCT07499219 | University of Oslo | N/A |
| Recruiting | Sexual Health Education During Pregnancy NCT07517549 | Ordu University | N/A |
| Not Yet Recruiting | Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals NCT07206381 | Istanbul Galata University | N/A |
| Recruiting | ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression NCT06408246 | Stanford University | Phase 2 |
| Not Yet Recruiting | GynMDD Add-On to Supportive Psychotherapy in Mild to Moderate Depression NCT07416747 | Fondation FondaMental | N/A |
| Not Yet Recruiting | Efficacy of a Culturally-adapted Mediterranean Diet Intervention on Depression in Relation to the Gut Microbio NCT07442799 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | Physical Activity Levels and Musculoskeletal Health Among Health Science Academicians at Istanbul Aydin Univer NCT07445100 | Istanbul Aydın University | — |
| Not Yet Recruiting | Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W- NCT07449338 | Vastra Gotaland Region | — |
| Not Yet Recruiting | Bridging the Gap: Implementing BRIDGES NCT07422909 | Université Catholique de Louvain | N/A |
| Not Yet Recruiting | Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Perioperative Negative Emotions in Breast Cancer NCT07458646 | Chinese PLA General Hospital | N/A |
| Not Yet Recruiting | Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Delirium and Negative Emotions in NCT07476742 | Chinese PLA General Hospital | N/A |
| Recruiting | Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depre NCT07449676 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Virtual Patient Groups for Sarcoidosis Associated Fatigue NCT07073963 | The Cleveland Clinic | N/A |
| Recruiting | Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High Scho NCT07240792 | Milton S. Hershey Medical Center | N/A |
| Recruiting | The BEAR Program for Women With Trauma Who Have Suicidal Thoughts NCT07346638 | Stanford University | N/A |
| Recruiting | Sound Bite-- a Therapeutic Song-writing Program NCT07371962 | City University of Hong Kong | N/A |
| Not Yet Recruiting | The PredictPlusPrevent Study NCT06351800 | The Mediterranean Institute for the Advance of Biotechnology and Health Research | N/A |
| Not Yet Recruiting | Prevention of ANxiety and Depression Over Risk Assessment NCT07185867 | The Mediterranean Institute for the Advance of Biotechnology and Health Research | N/A |
| Recruiting | Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital NCT07359157 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | Telehealth Music Therapy for Adults With Endocrine Disorder and Depression NCT07413874 | Appalachian State University | N/A |
| Not Yet Recruiting | Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal NCT07376395 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms NCT07469462 | University of Reading | N/A |
| Not Yet Recruiting | Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis NCT07319338 | China Academy of Chinese Medical Sciences | — |
| Not Yet Recruiting | A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Sel NCT07115381 | Lei Huang | N/A |
| Not Yet Recruiting | Blended Unified Protocol for Emotional Disorders in Primary Care NCT07432906 | Aydin Adnan Menderes University | N/A |
| Not Yet Recruiting | Effects of Craniosacral Therapy in Primary Caregivers of Individuals With Special Needs NCT07443527 | Istanbul Rumeli University | N/A |
| Withdrawn | The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 | Goddess Zena I. Jones | N/A |
| Recruiting | Lakota Family Acceptance Project NCT07326748 | University of Michigan | N/A |
| Not Yet Recruiting | Effects of Circadian-Based Acupressure on Sleep Quality in Nursing Home Residents NCT07349446 | Taipei Medical University | N/A |
| Not Yet Recruiting | Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depressi NCT07374211 | Chinese PLA General Hospital | N/A |
| Not Yet Recruiting | Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Su NCT07374198 | Chinese PLA General Hospital | N/A |
| Not Yet Recruiting | Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery NCT07367542 | Chinese PLA General Hospital | N/A |
| Recruiting | Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors NCT07091968 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | Interactive Technological Intervention to Improve Mental Health Symptoms in Primary Health Care NCT06692842 | University of Sao Paulo General Hospital | N/A |
| Recruiting | Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Ca NCT07364825 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Self-Affirmation Intervention After Mastectomy NCT07355244 | Muş Alparslan University | N/A |
| Not Yet Recruiting | Implementation of Internet-based Psychotherapy for Symptoms of Depression, Insomnia and Anxiety in Primary Car NCT06817109 | University of Sao Paulo General Hospital | N/A |
| Not Yet Recruiting | Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury NCT07224165 | Northwestern University | N/A |
| Not Yet Recruiting | Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression NCT07174557 | Dartmouth-Hitchcock Medical Center | N/A |
| Not Yet Recruiting | Effectiveness of a Guided Self-Help CBT Manual 'KOK' in Cancer Patients NCT07236164 | Pakistan Association of Cognitive Therapists | N/A |
| Recruiting | Just-in-Time Training for Youth Mentors NCT07129070 | University of Minnesota | N/A |
| Recruiting | Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure. NCT07319117 | Leeds Beckett University | N/A |
| Recruiting | Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients NCT07392879 | University of Michigan | N/A |
| Recruiting | Incidence of Depression and Its Complications After Surgical Site Infection - ISODEP. NCT07125196 | University Hospital, Bordeaux | N/A |
| Not Yet Recruiting | Using Virtual Reality Technology on Depression, Anxiety, and Stress Among Palestinian Patients Undergoing Brea NCT07267741 | Nablus University for Vocational and Technical Education | N/A |
| Not Yet Recruiting | Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders NCT07268729 | University of Toronto | — |
| Not Yet Recruiting | Transparent Communication to Improve Mental Wellbeing and Attitude Towards Reintegration NCT07251478 | Teesside University | N/A |
| Recruiting | A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder NCT06793397 | Cybin IRL Limited | Phase 3 |
| Recruiting | Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression NCT06419439 | VA Office of Research and Development | Phase 2 |
| Recruiting | Improving Treatment for Depression in General Practice Using a Step-by-Step Care Plan. NCT07263321 | Aalborg University Hospital | N/A |
| Not Yet Recruiting | Influence of a PSychological Intensive Support Program for Lung Cancer Patients ON Post-operative Outcomes. NCT07260227 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Completed | ACTing Minds: An ACT-based Videogame for Mental Health NCT07272096 | Swansea University | N/A |
| Recruiting | Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study NCT07247968 | Min Su | EARLY_Phase 1 |
| Enrolling By Invitation | Deep Versus Standard Prolonged Intermittent Theta Burst Stimulation for Depression NCT07198438 | National Taiwan University Hospital | N/A |
| Enrolling By Invitation | Treatment of SSD With tcVNS and taVNS NCT07198542 | National Taiwan University Hospital | N/A |
| Recruiting | Neural Mechanisms of Temporal Interference Stimulation on Improving Social Reward Function in Depression NCT07287878 | Shanghai Mental Health Center | N/A |
| Not Yet Recruiting | Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care NCT07236437 | Scott A. Irwin, MD, PhD | N/A |
| Recruiting | Therapeutic Music Listening in Post Stroke Patients. NCT07432204 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Recruiting | Efficacy of Narrative Therapy for Older People With Depression NCT07371988 | City University of Hong Kong | N/A |
| Not Yet Recruiting | Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial NCT07223736 | University of California, San Diego | N/A |
| Recruiting | Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients NCT06903819 | Texas Tech University Health Sciences Center | Phase 4 |
| Recruiting | Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study NCT07227337 | Johns Hopkins University | N/A |
| Recruiting | Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners NCT07220486 | Massachusetts General Hospital | N/A |
| Completed | Using Conversational AI to Teach Growth Mindset Skills to Youths in India NCT07316647 | Harvard University | N/A |
| Recruiting | Dapagliflozin in Depression NCT07239011 | Tanta University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Mediterranean Diet and the Microbiota Gut Brain Axis in Major Depression NCT04772651 | Medical University of Graz | N/A |
| Not Yet Recruiting | Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic NCT06644573 | Nyree Penn | Phase 1 |
| Not Yet Recruiting | A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety NCT06820723 | Ohio State University | Phase 2 |
| Recruiting | The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network NCT07066631 | Women's College Hospital | N/A |
| Recruiting | Parent Encouragement And Coaching of Happiness in Youth NCT06725160 | University of Pittsburgh | N/A |
| Recruiting | Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit NCT07173205 | East Carolina University | N/A |
| Recruiting | Readiness and Progress in Emotion Regulation Therapy NCT07478393 | Teachers College, Columbia University | N/A |
| Recruiting | Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Card NCT07143357 | Massachusetts General Hospital | N/A |
| Recruiting | Social Needs Screening and Chronic Diseases Study (WE CARE) NCT06903897 | University of Massachusetts, Worcester | N/A |
| Recruiting | Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment NCT07221409 | Mayo Clinic | N/A |
| Recruiting | Evaluating the Impact AI Avatar-led Mental Health Interventions for Keeping Employees in Work NCT07436117 | University of Roehampton | N/A |
| Not Yet Recruiting | Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients NCT06026709 | Peking Union Medical College | N/A |
| Recruiting | Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Pati NCT06707012 | Fazaia Ruth Pfau Medical College | Phase 4 |
| Not Yet Recruiting | Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in NCT06996054 | Fundació d'investigació Sanitària de les Illes Balears | N/A |
| Recruiting | Fluoxetine on Emotional Experience (FLEX) Study NCT07424781 | University of Oxford | N/A |
| Recruiting | Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay NCT06294119 | IRCCS Policlinico S. Donato | N/A |
| Recruiting | Improving Care and Mental Well-Being for Adults With Heart Failure NCT07313657 | Bruyère Health Research Institute. | N/A |
| Recruiting | Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU NCT07351799 | Mayo Clinic | N/A |
| Recruiting | Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia NCT07187492 | Xijing Hospital of Digestive Diseases | Phase 4 |
| Recruiting | Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia NCT07182890 | Xijing Hospital of Digestive Diseases | Phase 4 |
| Recruiting | Effectiveness of the Safe Haven Application (App) Among Undergraduates NCT07340983 | National Cheng-Kung University Hospital | N/A |
| Recruiting | Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention NCT07235852 | Khyber Medical University Peshawar | N/A |
| Recruiting | Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression NCT07082998 | Massachusetts General Hospital | N/A |
| Recruiting | Community-based Approach to Lowering Stress Through Mindfulness NCT06987799 | Northwestern University | N/A |
| Recruiting | Assessment of Music Experiences in Navigating Depression Part 2 NCT07218055 | Icahn School of Medicine at Mount Sinai | N/A |
| Active Not Recruiting | Neonatal Neurodevelopmental Outcomes NCT07101757 | Baylor College of Medicine | — |
| Active Not Recruiting | Nano-Learning for Improving Compliance Among Older Adults With Sarcopenia NCT07185763 | Alexandria University | N/A |
| Not Yet Recruiting | Effect of Music Activities on Depression and Sleep Quality in Frail Older Adults NCT07049445 | National Chung Hsing University | N/A |
| Not Yet Recruiting | Use of Virtual Reality as a Tool for Cognitive Remediation in Elderly Depressed Patients NCT07119008 | University Hospital, Brest | N/A |
| Not Yet Recruiting | Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life Depression NCT06591091 | University of Illinois at Chicago | Phase 2 |
| Recruiting | Effect of Vagal Nerve Stimulation on Gastric Motor Functions NCT06038929 | Mayo Clinic | N/A |
| Not Yet Recruiting | Multimodal Identification of Depressive Symptoms in the Elderly NCT07112118 | Wuhan Mental Health Centre | — |
| Recruiting | Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Qui NCT07118722 | Massachusetts General Hospital | N/A |
| Enrolling By Invitation | Multifaceted Benefits of Auricular Point Sticking for IVF Patients: Psychological Well-being, Sleep, and Treat NCT07409792 | Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University | N/A |
| Recruiting | Psilocybin-Assisted Therapy for Intergenerational Trauma NCT06899165 | Rachel Yehuda | Phase 2 |
| Active Not Recruiting | Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Dis NCT06545071 | University of Minnesota | Phase 1 |
| Not Yet Recruiting | Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Stude NCT07139249 | Cairo University | N/A |
| Recruiting | Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD) NCT07111390 | NYU Langone Health | N/A |
| Not Yet Recruiting | Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in Nigeria NCT07110831 | University of Ibadan | Phase 4 |
| Enrolling By Invitation | The University of Oregon ACCESS Project NCT07264621 | University of Oregon | N/A |
| Recruiting | fMRI Neurofeedback With Matter Neuroscience App NCT06735885 | Stanford University | N/A |
| Recruiting | Optimizing Care for Cancer Survivors With Depression: Project 3 NCT06930729 | Medical University of South Carolina | N/A |
| Recruiting | Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS) NCT06901687 | NYU Langone Health | Phase 2 |
| Recruiting | Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Sympto NCT07064551 | The University of Hong Kong | N/A |
| Not Yet Recruiting | Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study NCT06974214 | Herlev Hospital | N/A |
| Recruiting | A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression NCT07112001 | University of Florida | N/A |
| Recruiting | Effectiveness of CAT-GSH for Returning Patients NCT06806176 | University of Sheffield | N/A |
| Recruiting | A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression NCT06597695 | Juliana Zambrano, MD, MPH | Phase 1 / Phase 2 |
| Recruiting | Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Chi NCT06262178 | New York University | N/A |
| Recruiting | Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course NCT07088939 | University of Windsor | N/A |
| Recruiting | Positive Processes and Transition to Health - Single-Session (PATH-SS) NCT06900712 | Case Western Reserve University | N/A |
| Not Yet Recruiting | Long-term Follow-up of Depressive Disorders in Psychiatric Care NCT07078227 | Region Skane | — |
| Recruiting | Validation of EmoDTx as a Digital Endpoint for Mood Monitoring in Adult Patients Suffering From Unipolar Depre NCT06860165 | Emobot | — |
| Recruiting | RCT for Latina Mental Health Using Web-Based Apps NCT06874790 | University of California, Los Angeles | N/A |
| Recruiting | Clinical Trial of TJ0113 Capsules in the Treatment of Patients With Depressive Disorder NCT07018245 | Hangzhou PhecdaMed Co., Ltd. | Phase 2 |
| Recruiting | Training Reward Responsiveness Through Virtual Reality NCT07219875 | University of California, Los Angeles | Phase 2 |
| Terminated | Mental Health App for Cancer Survivors Study NCT06472726 | University of Wisconsin, Madison | N/A |
| Recruiting | Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons NCT06923423 | University of Arkansas | N/A |
| Recruiting | A Study of Ketamine Infusions to Treat Clinically-depressed ICU Patients NCT05803551 | Mayo Clinic | Phase 2 |
| Not Yet Recruiting | StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression NCT06567340 | Rotherham Doncaster and South Humber NHS Foundation Trust | N/A |
| Recruiting | Electroacupuncture on Treating Cancer-related Depression NCT07003763 | Shanghai Municipal Hospital of Traditional Chinese Medicine | N/A |
| Recruiting | Brain STimulation for ANxiety and Depression in Youth NCT06892847 | University of Calgary | N/A |
| Not Yet Recruiting | Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood NCT07033520 | Fundación Cardiovascular de Colombia | N/A |
| Recruiting | Researching Heat and Yoga for Mood Enhancement NCT06094088 | Massachusetts General Hospital | N/A |
| Recruiting | SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families NCT06627764 | Duke University | N/A |
| Recruiting | Identifying and Treating Depression in the Orthopaedic Trauma Population NCT05976347 | Wake Forest University Health Sciences | Phase 4 |
| Not Yet Recruiting | Effect of Laughter Therapy on Breast Cancer Patients NCT07020962 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | N/A |
| Recruiting | Optimizing Suicide Prevention Strategies for Pediatric Primary Care NCT06194331 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Nalbuphine Dosing and Its Impact on Anxiety and Depression in Ectopic Pregnancy Surgery NCT07009808 | Chengdu Jinjiang Maternity and Child Health Hospital | N/A |
| Recruiting | Ecological Momentary Intervention for Reward in Anhedonia NCT07155941 | Philipps University Marburg | N/A |
| Recruiting | Enhancing Internet-Delivered Cognitive Behaviour Therapy With Additional Content NCT07095582 | University of Regina | N/A |
| Not Yet Recruiting | Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life NCT07005596 | Far Eastern Memorial Hospital | N/A |
| Recruiting | Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Communi NCT07179172 | Taipei Medical University Shuang Ho Hospital | N/A |
| Recruiting | E-Mindfulness Approaches for Living After Breast Cancer NCT06748222 | NRG Oncology | Phase 3 |
| Recruiting | Mood Effects of Serotonin Agonists: Depression NCT07017478 | University of Chicago | EARLY_Phase 1 |
| Recruiting | Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries NCT06812247 | Boston Medical Center | N/A |
| Recruiting | Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms NCT06786936 | NHS Greater Glasgow and Clyde | — |
| Active Not Recruiting | The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. NCT06993662 | Rakitzi, Stavroula | Phase 1 |
| Recruiting | Cocooned Moms Study NCT06968650 | InovCares Connected Comprehensive Healthcare Corporation | N/A |
| Not Yet Recruiting | From Fear to Purpose ACT Protocol. Implications of Death Anxiety in Depression and Anxiety Symptoms. NCT06810999 | Babes-Bolyai University | N/A |
| Recruiting | Change My Story Task Shifted Mental Health Intervention NCT06389565 | Massachusetts General Hospital | N/A |
| Recruiting | TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survi NCT06801041 | M.D. Anderson Cancer Center | Phase 2 |
| Recruiting | Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions NCT06557005 | Massachusetts General Hospital | N/A |
| Recruiting | Assessing Improvements in Mood and Sleep Trial NCT06639477 | University of Pittsburgh | N/A |
| Recruiting | Implementation of DWM in Dutch SMEs NCT06979089 | VU University of Amsterdam | N/A |
| Recruiting | Probiotic Administration for Adolescent Depression NCT06898788 | University of California, San Francisco | EARLY_Phase 1 |
| Recruiting | Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments NCT06997549 | Neuronetics | — |
| Recruiting | Investigation to Understand and Optimize Psilocybin NCT06512194 | Charles Raison | Phase 2 |
| Completed | Low Load With Blood Flow Restriction for Improving Strength, Balance, and Cognition in Older Adults NCT06962514 | Sahmyook University | N/A |
| Recruiting | Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS NCT06963463 | University of Pittsburgh | N/A |
| Enrolling By Invitation | Social Media Intervention for Online Victimized Youth NCT06835985 | University of Pittsburgh | N/A |
| Active Not Recruiting | Screening and Referral Practices for Anxiety and Depression Among Patients With Chronic Neck, Shoulder and Low NCT07177547 | Ana Catarina Navarro Ramalho | — |
| Recruiting | Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression NCT06384196 | University of Barcelona | N/A |
| Not Yet Recruiting | Treating Common Mental Disorders in Women in Mozambique by Addressing Intimate Partner Violence in Couples NCT06252909 | New York State Psychiatric Institute | N/A |
| Not Yet Recruiting | RCT Protocol for 'OverThinking': A Mobile EMI for Reducing Experiential Avoidance NCT06570694 | University of Social Sciences and Humanities, Warsaw | N/A |
| Not Yet Recruiting | Neurocardiac Predictors of Treatment Response to RTMS in Depression NCT05139862 | University of British Columbia | N/A |
| Recruiting | Project neuroARTEMIS NCT06814275 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) NCT06942637 | National University of Singapore | N/A |
| Recruiting | Family Acceptance Project Online (Pilot RCT) NCT06839859 | University of Michigan | Phase 2 |
| Not Yet Recruiting | Depression Among Cardiothoracic Surgery Patients in Baghdad NCT06734169 | Al-Nahrain University | — |
| Recruiting | Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women NCT06353113 | San Diego State University | N/A |
| Recruiting | Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Af NCT05624931 | Boston University Charles River Campus | N/A |
| Recruiting | Income Volatility and Mental Health, Full Experiment NCT06988410 | Cornell University | N/A |
| Active Not Recruiting | Group Cognitive Evolutionary Therapy for Depression NCT06359769 | University of Bucharest | N/A |
| Recruiting | Filipino Family Health Initiative 1.0 NCT06569303 | Kaiser Permanente | N/A |
| Recruiting | Improving Mental Health in Forcibly Displaced Populations NCT06635486 | Boston Medical Center | N/A |
| Enrolling By Invitation | Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya NCT06489314 | Florida International University | N/A |
| Recruiting | Effects of Spirulina Supplementation on Mental Health in Healthy Adults NCT06936202 | Arizona State University | N/A |
| Recruiting | Developing Resilience and Anxiety Management Through the Arts NCT07033052 | Case Western Reserve University | N/A |
| Recruiting | Neuroscience of Psychotherapy for Depression NCT06696001 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Internet-Delivered Psychological Treatment for Cancer Survivors NCT06046586 | Karolinska Institutet | N/A |
| Recruiting | Visual Frailty in Ageing NCT06604104 | University of Edinburgh | — |
| Recruiting | Aligning Facility Leadership and Climate to Advance Mental Health Services Integration in Malawi NCT06399991 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal NCT06834867 | Possible | N/A |
| Enrolling By Invitation | Clinical and Psychosocial Characteristics of Adolescent Patients With Non-Suicidal Self-Injury NCT06885749 | Xijing Hospital | — |
| Not Yet Recruiting | Evaluation of an Asynchronous Remote Communities Approach to Behavioral Activation for Depressed Adolescents NCT06786247 | University of Washington | N/A |
| Completed | The Effect of Mobile Application-Based Education Given to Patients With Tracheostomy on Depression, Social Ada NCT07337668 | Saglik Bilimleri Universitesi | N/A |
| Completed | Treating Psychosocial Distress in Glaucoma NCT06053307 | Duke University | N/A |
| Recruiting | Pharmacologic Augmentation of TMS for Depression With D-serine NCT06876129 | Mclean Hospital | Phase 1 |
| Not Yet Recruiting | Heart Rate Variability and Music Listening NCT06929208 | KK Women's and Children's Hospital | N/A |
| Completed | Teach Back Method on Depression Levels in Hemodialysis Patients NCT07069634 | Saglik Bilimleri Universitesi | N/A |
| Enrolling By Invitation | Depression, Illness Perception, and Erectile Dysfunction Outcomes NCT06996925 | Haseki Training and Research Hospital | — |
| Completed | Cross-Cultural Differences in the Network Structure of Social Anxiety and Body Dysmorphic Symptoms NCT06962917 | Philipps University Marburg | — |
| Recruiting | Dosing rTMS for Depression Post-SCI NCT05553353 | VA Office of Research and Development | N/A |
| Recruiting | Kintsugi Voice Device Pivotal Study NCT06809907 | Kintsugi Mindful Wellness, Inc. | — |
| Active Not Recruiting | Integrating Depression Care Into HIV Services for Older People With HIV Using a Stepped Care, Task-Sharing App NCT06894680 | Royal Society of Tropical Medicine and Hygiene | N/A |
| Recruiting | Teen Brain Online II: Understanding How Social Media Affects the Teen Brain NCT06817993 | University of Pittsburgh | N/A |
| Completed | Primary Care-based Study of an Online Workshop for Family Caregivers of PLWD NCT06928467 | University of California, San Francisco | N/A |
| Recruiting | Accelerated iTBS for Depression: Monitoring Brain Hemodynamics With Simultaneous iTBS/fNIRS NCT06971549 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Antidepressant Adherence for Depressed Adults in Primary Care NCT06496646 | University of Pennsylvania | N/A |
| Recruiting | Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST) NCT05942469 | Northwestern University | N/A |
| Recruiting | Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans NCT06671977 | Deepak C. D'Souza | Phase 1 |
| Recruiting | Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU) NCT06627894 | Indiana University | N/A |
| Recruiting | Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction NCT06678880 | University of California, San Diego | N/A |
| Recruiting | Self-Help Plus for Distress in University Students NCT06606249 | University of Padova | N/A |
| Enrolling By Invitation | Effects of Tuijing Therapy on Heart Rate Variability and Psychological Symptoms NCT06888284 | The Hong Kong Polytechnic University | N/A |
| Enrolling By Invitation | Acute Psychological Sleep Stabilisation for Patients Hospitalised With Depression NCT06145555 | Karolinska Institutet | N/A |
| Recruiting | Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II NCT06867549 | Washington University School of Medicine | Phase 2 |
| Not Yet Recruiting | Behavioural Activation and Severe Learning Disabilities NCT06851741 | NHS Greater Glasgow and Clyde | N/A |
| Recruiting | Neural and Psychiatric Consequences of Cannabis Use in Adolescents NCT06941298 | University of Miami | N/A |
| Not Yet Recruiting | Biopsychosocial Effects of Gardening Activities NCT06844084 | Ordu University | N/A |
| Not Yet Recruiting | Precision Transcranial Magnetic Stimulation for Depression Based on Orbital Frontal Cortex-habenula Circuitry NCT06837207 | Xijing Hospital | N/A |
| Recruiting | Death Anxiety, Depression and Anxiety: An Experimental Study NCT07201480 | Babes-Bolyai University | N/A |
| Completed | Qigong Relaxation Exercise NCT07294443 | Saglik Bilimleri Universitesi | N/A |
| Not Yet Recruiting | Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults with SCI NCT06708026 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Impact of Depression on Thermoregulation NCT06805851 | Penn State University | — |
| Completed | Dyspnea and Psychosocial Effects of Hand Fan Application in COPD Patients NCT06857422 | Ardahan University | N/A |
| Recruiting | Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes NCT06702722 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity NCT06831994 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Recruiting | Retrospective Analyses of TrakStar Database NCT06917339 | Neuronetics | — |
| Recruiting | Mobile Cognitive Behavioral Therapy for Stroke NCT06689878 | Weill Medical College of Cornell University | N/A |
| Recruiting | Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents NCT06881693 | University of Regina | N/A |
| Completed | The Effect of Mandala Coloring on Depression, Anxiety and Quality of Life of Inpatients in a Psychiatric Clini NCT06840171 | reyhan eskiyurt | N/A |
| Recruiting | Cannabis, Linked Emotions, and Adolescent Risk Study NCT06576076 | Massachusetts General Hospital | N/A |
| Recruiting | Potential Benefits of Parent Child Interaction Therapy (PCIT) NCT06827951 | University of Florida | — |
| Recruiting | Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer NCT06687291 | Karolinska Institutet | — |
| Recruiting | 7T Amygdala and Citalopram Study NCT06412315 | University of Oxford | N/A |
| Completed | Validity and Reliability of the Turkish Version of the Cardiac Depression Scale NCT06836804 | Kırıkkale University | — |
| Completed | The Effectiveness of Acceptance and Commitment Therapy (ACT) on Dysfunctional Attitudes and Difficulties in Em NCT07256093 | Universiti Sains Malaysia | N/A |
| Completed | Effects of a 10-Week Zumba Program on Anxiety and Depression in Adults NCT07317908 | Manuel Jesús Rodríguez Chavarría | N/A |
| Not Yet Recruiting | Stepped Care Model of Lifestyle-based Mental Health Care for Depression NCT06825507 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | The Efficacy of Lavender Herbal Tea in Misophonia NCT06785649 | Sakarya University | N/A |
| Recruiting | Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program NCT05789446 | Penn State University | N/A |
| Not Yet Recruiting | The Impact of a Home-Based Walking Exercise Program on Heart Failure NCT06791967 | National Taiwan University Hospital | N/A |
| Completed | Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined Methotrexate and Antidepre NCT07432815 | Cairo University | Phase 4 |
| Enrolling By Invitation | EMDR Versus Imagery Rescripting for Trauma-Related Intrusions NCT06215313 | Geestelijke Gezondheidszorg Eindhoven (GGzE) | N/A |
| Active Not Recruiting | Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression NCT06317636 | Stanford University | Phase 4 |
| Recruiting | Conversations With Caregivers About Health and Appearance NCT06843200 | University of Oregon | N/A |
| Recruiting | PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study NCT06713616 | Yale University | Phase 3 |
| Recruiting | Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Inflammation and Depression Following SCI NCT06493071 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Vibraimage Technology for Detecting Depression in Psychiatric Outpatients NCT06793176 | Peking University People's Hospital | — |
| Recruiting | CAPABLE Transplant NCT06326905 | Johns Hopkins University | N/A |
| Recruiting | Digital InteGrated Behavioral TreatmeNt for Comorbid ObesITy and DeprEssion Among Racial and Ethnic Adults Age NCT06636058 | University of Illinois at Chicago | N/A |
| Recruiting | Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease NCT05568498 | University of British Columbia | Phase 2 |
| Recruiting | Stress and Pain in People Living With HIV NCT06784908 | Yale University | N/A |
| Completed | Community Based Mental Health Screening and Referral NCT06756165 | Dr Jai Kumar Das | N/A |
| Not Yet Recruiting | Improvement of Depression in Terminal Cancer Patients NCT06785623 | National Taiwan University Hospital | N/A |
| Completed | Adaptive Messaging to Support Depression Self-Management NCT06458192 | Northwestern University | N/A |
| Recruiting | Michigan Men's Diabetes Project III(MenDIII): Mind and Motion NCT06574035 | University of Michigan | N/A |
| Recruiting | The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program NCT06652503 | Nova Southeastern University | N/A |