Trials / Sponsors / NRG Oncology
NRG Oncology
Academic / Other · 68 registered clinical trials — 28 currently recruiting.
| Status | Trial | Phase | Started |
|---|---|---|---|
| Not Yet Recruiting | Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cann Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 3 | 2027-01-06 |
| Not Yet Recruiting | Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Dia Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma | Phase 3 | 2026-06-08 |
| Recruiting | Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Canc Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8 | Phase 3 | 2026-02-26 |
| Recruiting | Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8 | Phase 3 | 2025-10-07 |
| Recruiting | Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8 | Phase 3 | 2025-08-21 |
| Recruiting | E-Mindfulness Approaches for Living After Breast Cancer Breast Cancer, Depression | Phase 3 | 2025-06-12 |
| Active Not Recruiting | Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causin Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm | Phase 3 | 2025-04-14 |
| Recruiting | Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma, FIGO Stage III Ovarian Cancer 2014 | Phase 3 | 2025-03-12 |
| Recruiting | Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Phase 3 | 2025-03-04 |
| Recruiting | Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy f Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | 2024-12-16 |
| Recruiting | Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma | Phase 3 | 2024-12-12 |
| Recruiting | Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During O Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | N/A | 2024-10-14 |
| Recruiting | Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors Breast Cancer, Cognitive Impairments | N/A | 2024-04-12 |
| Recruiting | Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prost Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8 | Phase 3 | 2023-12-14 |
| Recruiting | Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Pre Breast Cancer | Phase 3 | 2023-08-31 |
| Recruiting | Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable N Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8 | Phase 3 | 2023-07-12 |
| Recruiting | Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Brea HER2-positive Breast Cancer | Phase 3 | 2023-03-13 |
| Recruiting | Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma, Stage III Major Salivary Gland Cancer AJCC v8 | Phase 2 | 2023-03-03 |
| Recruiting | Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | Phase 2 | 2023-02-01 |
| Recruiting | Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometr Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 | Phase 3 | 2022-12-07 |
| Active Not Recruiting | Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases Metastatic Malignant Neoplasm in the Brain | Phase 3 | 2022-10-24 |
| Active Not Recruiting | Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, Oligometastatic Prostate Carcinoma, Prostate Adenocarcinoma, Prostate Ductal Adenocarcinoma | Phase 2 | 2022-04-20 |
| Active Not Recruiting | Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and R Glioblastoma, Gliosarcoma | Phase 3 | 2022-03-28 |
| Recruiting | Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease Stage III Colon Cancer | Phase 2 / Phase 3 | 2022-03-10 |
| Recruiting | Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | N/A | 2022-02-09 |
| Suspended | Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advan Advanced Head and Neck Squamous Cell Carcinoma, Advanced Hypopharyngeal Squamous Cell Carcinoma, Advanced Laryngeal Squamous Cell Carcinoma | Phase 2 / Phase 3 | 2022-02-01 |
| Active Not Recruiting | Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Prostate Adenocarcinoma | Phase 3 | 2021-12-06 |
| Active Not Recruiting | Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advance Advanced Esophageal Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma, Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Phase 1 | 2021-12-02 |
| Terminated | Testing the Addition of Activity Monitoring With a Wearable Electronic Device to Improve Patient Care During T Non-small Cell Lung Cancer, Non-small Cell Lung Cancer Stage III, Recurrent Non Small Cell Lung Cancer | N/A | 2021-08-26 |
| Terminated | Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma | Phase 3 | 2021-08-05 |
| Recruiting | Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma | Phase 3 | 2021-06-10 |
| Recruiting | De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Stage I Breast Cancer | Phase 3 | 2021-06-07 |
| Active Not Recruiting | Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8 | Phase 3 | 2021-01-21 |
| Recruiting | Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Ca Buccal Mucosa Squamous Cell Carcinoma, Floor of Mouth Squamous Cell Carcinoma, Gingival Squamous Cell Carcinoma | Phase 2 / Phase 3 | 2020-09-23 |
| Recruiting | A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovari Ovarian Carcinoma | N/A | 2020-09-01 |
| Recruiting | Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Phase 3 | 2020-04-16 |
| Withdrawn | Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolom Anaplastic Astrocytoma, Glioblastoma, Oligodendroglioma | Phase 2 / Phase 3 | 2020-01-31 |
| Terminated | Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed Pleural Biphasic Mesothelioma, Pleural Epithelioid Mesothelioma, Stage I Pleural Malignant Mesothelioma AJCC v8 | Phase 3 | 2020-01-29 |
| Active Not Recruiting | Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol Malignant Solid Neoplasm | Phase 1 | 2020-01-15 |
| Active Not Recruiting | Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery Colon Adenocarcinoma, Stage IIA Colon Cancer AJCC v8 | Phase 2 / Phase 3 | 2019-12-16 |
| Completed | Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Thera Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8 | Phase 1 / Phase 2 | 2019-10-08 |
| Active Not Recruiting | Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma | Phase 3 | 2019-09-20 |
| Completed | Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Prostate Adenocarcinoma | N/A | 2019-07-26 |
| Recruiting | Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 3 | 2019-06-26 |
| Active Not Recruiting | Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Recurrent Prostate Carcinoma, Stage III Prostate Adenocarcinoma AJCC v7, Stage IV Prostate Adenocarcinoma AJCC v7 | Phase 2 | 2018-06-20 |
| Active Not Recruiting | Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage I Stage II Prostate Adenocarcinoma AJCC v7 | Phase 3 | 2018-02-01 |
| Active Not Recruiting | Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer Recurrent Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v7, Unresectable Hepatocellular Carcinoma | Phase 3 | 2018-01-26 |
| Active Not Recruiting | Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma | Phase 2 | 2018-01-23 |
| Recruiting | Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been C Grade 2 Meningioma, Intracranial Meningioma | Phase 3 | 2017-09-12 |
| Completed | Hypofractionated Radiation Therapy or Conventional Radiation Therapy After Surgery in Treating Patients With P Prostate Adenocarcinoma, Stage I Prostate Adenocarcinoma AJCC v7, Stage II Prostate Adenocarcinoma AJCC v7 | Phase 3 | 2017-07-28 |
| Completed | Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer Breast Carcinoma, Cervical Carcinoma, Ovarian Carcinoma | Phase 2 | 2017-05-31 |
| Completed | Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery Invasive Breast Carcinoma, Stage II Breast Cancer, Stage IIA Breast Cancer | Phase 2 | 2017-04-13 |
| Active Not Recruiting | Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-sm Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer | Phase 2 | 2017-04-07 |
| Completed | Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer Stage I Prostate Adenocarcinoma AJCC v7, Stage II Prostate Adenocarcinoma AJCC v7, Stage III Prostate Adenocarcinoma AJCC v7 | Phase 2 / Phase 3 | 2017-04-05 |
| Completed | Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma | Phase 1 / Phase 2 | 2016-11-14 |
| Completed | Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma | Phase 2 | 2016-09-16 |
| Completed | Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Extensive Stage Small Cell Lung Carcinoma, Limited Stage Small Cell Lung Carcinoma | Phase 2 / Phase 3 | 2015-12-22 |
| Active Not Recruiting | Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Breast Adenocarcinoma, Estrogen Receptor Negative, HER2/Neu Negative | Phase 3 | 2015-07-26 |
| Completed | Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neuroco Cognitive Impairment, Metastatic Malignant Neoplasm in the Brain, Solid Neoplasm | Phase 3 | 2015-07-01 |
| Completed | Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Und Endometrial Serous Adenocarcinoma, Fallopian Tube Carcinoma, Malignant Female Reproductive System Neoplasm | — | 2015-02-10 |
| Terminated | Surgery With or Without Postoperative Intensity Modulated Radiation Therapy in Treating Patients With Urotheli Stage III Bladder Cancer, Stage IV Bladder Cancer | Phase 2 | 2015-02-01 |
| Completed | Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8, Metastatic Breast Carcinoma, Metastatic Malignant Neoplasm in the Bone | Phase 2 / Phase 3 | 2014-12-24 |
| Active Not Recruiting | Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozol Glioblastoma | Phase 2 | 2014-12-04 |
| Completed | Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advance Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma | Phase 2 | 2014-10-01 |
| Terminated | Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer Stage III Intrahepatic Cholangiocarcinoma, Stage IVA Intrahepatic Cholangiocarcinoma | Phase 3 | 2014-09-29 |
| Completed | Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Adenosquamous Lung Carcinoma, Bronchioloalveolar Carcinoma, Large Cell Lung Carcinoma | Phase 2 | 2014-08-01 |
| Completed | Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Ca Male Breast Carcinoma, Prostate Adenocarcinoma, Recurrent Breast Carcinoma | Phase 1 | 2014-08-01 |
| Active Not Recruiting | Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA Epstein-Barr Virus Infection, Stage II Nasopharyngeal Carcinoma, Stage III Nasopharyngeal Carcinoma | Phase 2 / Phase 3 | 2014-04-21 |