NCT06496646

Antidepressant Adherence for Depressed Adults in Primary Care

Antidepressant Medication Adherence in Adults With Depression

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 525 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 21 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

Detailed description

Participants in the study will be given a special pill bottle for depression medication. This pill bottle will track how often the bottle is opened to take medication and it will transmit that information to the research team. Participation will last 12 weeks, and will include an initial assessments over the phone and follow-up assessments over the phone or electronically approximately 6 weeks and 12 weeks later. During these assessments, a research coordinator will ask questions about your mood, quality of life, participation in the management of depression, and related topics.

Conditions

• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Arm 1 intervention	This description is blinded.
BEHAVIORAL	Arm 2 Intervention	This description is blinded

Timeline

• Start date: 2025-03-19
• Primary completion: 2029-03-31
• Completion: 2029-03-31
• First posted: 2024-07-11
• Last updated: 2025-11-26

Locations

1 site across 1 country: United States