NCT07452341

Effect of Virtual Reality on Depression in Adolescent Females

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: 13 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effect of virtual reality on depression in adolescent females.

Detailed description

Depression is most commonly found in adolescents and large percentage of them don't receive management. People with depression usually experience at least five of the following 9 characteristics: (1) people feel sad and unhappy; (2) have less interest in doing things; (3) individuals do not follow a diet, but their weight losses are obvious; (4) their appetites change and their weight may increase; (5) they suffer insomnia or drowsiness; (6) some people have mental agitation; (7) they feel that life is meaningless, or they feel guilty; (8) they have difficulty concentrating; or (9) they have suicidal thoughts . Individuals who develop depression may have experienced an anxiety disorder earlier in life. Depression is most commonly found in adolescents and large percentage of them don't receive management The application of emerging technology in health promotion has generated substantial public interest. Among the emerging technologies that may potentially aid in the treatment of depression, virtual reality (VR) is the most exciting and technologically-advanced. A virtual environment provides a greater degree of control for the therapists to customize, reproduce, and tweak several treatment parameters according to the patient's needs.

Conditions

• Depression

Interventions

Type	Name	Description
DEVICE	Virtual reality headset	Participants will use virtual reality glasses during treatment sessions for approximately 30 minutes per session, once per week for 8 weeks .
DRUG	Selective serotonin reuptake inhibitors(SSRIs)	All adolescent females in the control group will receive antidepressant drugs Selective serotonin reuptake inhibitors(SSRIs) for 8 weeks as described by the psychiatrist

Timeline

• Start date: 2026-08-01
• Primary completion: 2027-01-01
• Completion: 2027-02-01
• First posted: 2026-03-05
• Last updated: 2026-03-11