NCT06536530

Benefits of Exergames on Neurocognitive Functions in Adults Suffering From Depression

MUDgame A Randomized Multi-Arm Controlled Experiment for Measuring the Benefits of an Exergame-based Intervention on Neuro-cognitive Functions in Adults Suffering From Depression

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: MAP Institute · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to analyse the changes derived from exergames (videogames that include cognitive and physical stimulation simultaneously), in terms of cognitive functioning, psychomotor abilities, and its neural substrate, in adults suffering from depression.

Detailed description

The experiment will consist in a randomized three-arms controlled study. After being informed about the study and potential risks, and given written informed consent, adult participants with depression will be randomly distributed into three experimental groups: an intervention group that will train with exergames, an active control group that will train only with cognitive games, and a passive control group or wait-list. Cognitive Functions will be evaluated in three different moments: before the training intervention, after the intervention, and three months after finishing the training intervention. Researchers will collect cognitive-behavioral and neural information (event-related potentials), and performing analysis of variance to compare the outcomes of the diverse groups at the three different time points, scientists will analyse the benefits of exergames on cognition.

Conditions

• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Exergame-Based Training	40-50 min sessions, two sessions per week, for a total of eight weeks.
BEHAVIORAL	Cognitive-Based Training	40-50 min sessions, two sessions per week, for a total of eight weeks.
BEHAVIORAL	Wait-List	Participants will not train with any program and they will not assist to any specific session or intervention

Timeline

• Start date: 2027-01-01
• Primary completion: 2028-02-01
• Completion: 2029-03-01
• First posted: 2024-08-05
• Last updated: 2025-07-17