Trials / Not Yet Recruiting
Not Yet RecruitingNCT07374211
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression
Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression: A Randomized Controlled Trial
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 242 (estimated)
- Sponsor
- Chinese PLA General Hospital · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This project employs a prospective, randomized, controlled, blinded, dual-center study design to investigate the effects of intraoperative esketamine on perioperative anxiety and depression symptoms in patients with severe depression undergoing breast cancer surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esketamine 0.3mg/kg | A single intravenous bolus of 0.3 mg/kg of esketamine is administered during anesthesia induction, and the infusion is completed over 40 minutes. |
| DRUG | normal saline | Receiving the same volume of normal saline during induction of anesthesia. |
Timeline
- Start date
- 2026-01-18
- Primary completion
- 2026-01-18
- Completion
- 2027-02-01
- First posted
- 2026-01-28
- Last updated
- 2026-01-28
Source: ClinicalTrials.gov record NCT07374211. Inclusion in this directory is not an endorsement.