Clinical Trials Directory

Trials / Sponsors / Case Western Reserve University

Case Western Reserve University

Academic / Other · 156 registered clinical trials27 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingREstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic St
Intracranial Atherosclerotic Disease, Stroke, Angioplasty, Balloon
N/A2027-10-01
Not Yet RecruitingKnowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
Elder Mistreatment, Elder Abuse, Quality of Care
Phase 22026-07-31
Not Yet RecruitingHumidity Asthma Interventions for Low Socioeconomic Status Children
Pediatric Asthma
N/A2026-04-01
Not Yet RecruitingREACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)
Schizophrenia, Schizo Affective Disorder, Schizophreniform Disorders
N/A2026-04-01
RecruitingEffect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics
Periodontitis, Diabetes Mellitus Type 2
EARLY_Phase 12026-02-06
RecruitingYouth Empowerment and Safety Intervention
Suicide, Self-Injurious Behavior
N/A2026-01-31
RecruitingDevelopment of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
N/A2026-01-13
Enrolling By InvitationEffect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years
Fuchs Endothelial Corneal Dystrophy, Corneal Endothelial Decompensation
N/A2025-12-03
Completed3D Modalities for Medical Student Education of Congenital Heart Disease
Tetralogy of Fallot (TOF), Hypoplastic Left Heart Syndrome (HLHS)
N/A2025-11-20
RecruitingLT Comparative Effectiveness of 2 Caries Treatments
Dental Caries
N/A2025-10-08
RecruitingNourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy
Pregnancy Related, Prematurity, Birth Outcome, Adverse
N/A2025-10-06
Enrolling By InvitationCommunity-Engaged Sleep Intervention for School-Aged Children With Autism Spectrum Disorder
Sleep Disturbance, Autism Spectrum Disorder
N/A2025-08-27
RecruitingPreventing Athlete Under-fueling Through Nutrition.
Athlete, Relative Energy Deficiency in Sport, Low Energy Availability
N/A2025-08-19
CompletedIncreasing Men's Engagement in Preventive Healthcare Through an Enhanced Cocoon Vaccination Strategy
Vaccines, Preventive Medicine
N/A2025-08-15
RecruitingPositive Processes and Transition to Health - Single-Session (PATH-SS)
PTSD, Depression
N/A2025-07-17
RecruitingImproving Sleep Health Outcomes for Family Caregivers
Family Caregivers, Sleep
N/A2025-06-26
RecruitingNourish Clinical Trial
Nutrition, Healthy
N/A2025-05-19
RecruitingDeveloping Resilience and Anxiety Management Through the Arts
Anxiety, Depression, Mood
N/A2025-04-15
RecruitingOral Health Intervention in Adult Primary Care
Dental Caries, Dry Mouth, Periodontal Diseases
N/A2024-09-25
CompletedEffect of Grapes in Inflammatory Bowel Disease
Crohn Disease
N/A2024-09-16
Active Not RecruitingThe Impact of Technology in Obstructive Sleep Apnea Myofunctional Therapy
Obstructive Sleep Apnea (OSA), Snoring, Sleep Quality
N/A2024-08-26
CompletedExparel Versus Bupivacaine in Post-operative Pain Control
Liposomal Bupivacaine
Phase 42024-08-21
CompletedNutrition for Health and Performance in Female Collegiate Soccer Players
Healthy
N/A2024-08-19
CompletedNourish Pilot & CoDesign Study
Nutrition, Healthy
N/A2024-07-25
CompletedTexting to Promote Breastfeeding (TOPS)
Increased Breastfeeding
N/A2024-07-15
CompletedCONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)
Alzheimer Disease, Dementia, Caregiver Burden
N/A2024-03-23
CompletedEvaluating Sleep Quality With Emerging Technologies
Snoring, Sleep Disturbances, Hypoxia
2024-02-10
Active Not RecruitingLearning Skills Together Family Caregiver Complex Intervention
Dementia, Alzheimer Disease, Caregiver Burden
N/A2024-01-30
RecruitingPositive Processes and Transition to Health (PATH)
Posttraumatic Stress Disorder, Major Depressive Disorder
N/A2023-09-12
Active Not RecruitingDiabetes Inspired Culinary Education (DICE): Culinary Medicine Intervention for At-Risk Youth With Type 1 Diab
Type 1 Diabetes
N/A2023-09-01
RecruitingClean Hands Accessible and Manageable for Patients (CHAMPs)
Pathogen Transmission, Patient Participation, Aging
N/A2023-08-17
RecruitingChanges in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
Edentulous Mouth, Periodontal Diseases, Periodontitis, Adult
2023-08-16
RecruitingComparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums
Recession, Gingival
N/A2023-05-19
CompletedKnowledge and Interpersonal Skills to Develop Exemplary Relationships (KINDER): Pilot Study
Dementia, Caregiver Burden, Relation, Family
N/A2023-03-13
Active Not RecruitingEnhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO;
Opioid Use Disorder, Pain
N/A2023-02-10
RecruitingImmediate Versus Delayed Loading of Maxillary Overdenture Implants
Implant Complication
N/A2023-02-01
RecruitingThe Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants
Apnea of Prematurity, Intermittent Hypoxemia, Bradycardia
N/A2022-09-16
Active Not RecruitingNourishing Beginnings: Addressing Food Insecurity During Pregnancy
Pregnancy Related, Food Insecurity, Premature Birth
N/A2022-07-01
CompletedA TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk Ugandans
Stroke
N/A2022-05-13
CompletedCONFIDENCE Financial Education for Caregivers
Caregiver Burden, Financial Stress, Dementia
N/A2022-05-01
CompletedSelf-Management in Young Adults With Type 1 Diabetes
Type 1 Diabetes
N/A2022-04-29
CompletedSelf-Management and Resilience Trajectories in African American Adults With Hypertension
Hypertension, Self-Management, Quality of Life
2022-03-01
CompletedAn Intervention to Promote Use of Smoking Cessation Resources Among Adults Using Community Food Pantries
Smoking Cessation, Food Insecurity
N/A2022-02-14
CompletedAn Intervention to Promote Smoking Cessation Among Adults With Food Insecurity
Smoking Cessation, Food Insecurity
N/A2022-02-10
Active Not RecruitingEffectiveness RCT of Customized Adherence Enhancement
Bipolar Disorder
N/A2022-02-01
CompletedImpact of Donor Diabetes on DMEK Success and Endothelial Cell Loss
Corneal Endothelial Decompensation, Fuchs' Endothelial Dystrophy
N/A2022-01-21
CompletedIMAS Optimization and Applicability in Acute and Subacute Stroke.
Acute Stroke
2021-10-29
CompletedPositive Processes and Transition to Health
Major Depressive Disorder, Post Traumatic Stress Disorder
N/A2021-10-01
CompletedAcupuncture in the Emergency Department for Pain Management
Acupuncture, Pain Management, Emergency Department
N/A2021-05-03
RecruitingOptimization of NIBS for Treatment of Addiction
Opioid-use Disorder, Chronic Pain
N/A2021-04-04
Active Not RecruitingUsing mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorde
Bipolar Disorder, Non-Adherence, Medication, Hypertension
N/A2021-03-15
CompletedImproving Adherence in Adolescents and Young Adults With Bipolar Disorder
Bipolar Disorder
N/A2021-03-15
CompletedOffering Support and Electronic Resources for Care Partners of Those With Multiple Sclerosis
Multiple Sclerosis, Caregivers
N/A2021-03-10
CompletedAssess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HI
HIV-1-infection, Hypertension
N/A2021-03-01
RecruitingOPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
Hypertension, Self-Management, Technology
N/A2021-02-14
CompletedEnhancing Exercise and Psychotherapy to Treat Pain and Addiction in Opioid Use Disorders ("EXPO" Pilot Trial)
Opioid-use Disorder, Pain
N/A2021-01-08
CompletedSelf-Management Intervention: Considering Needs & Preferences of Dementia Caregivers (Caregiver Career Study)
Stress, Carer Stress Syndrome, Dementia
N/A2021-01-08
CompletedPictographic Education Handout on Tracheostomy Care
Health Literacy
N/A2020-10-01
CompletedReducing Stroke Risk in African-American Men
Stroke, Transient Ischemic Attack
N/A2020-05-05
CompletedReducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY)
Schizophrenia, Medication Nonadherence, Schizo Affective Disorder
Phase 32019-11-05
CompletedA Dietary Intervention Study on the Microbiome in Crohn's Disease Patients
Crohn Disease
N/A2019-11-01
CompletedA Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention
HIV/AIDS, Hypertension, Hyperlipidemias
N/A2019-09-20
CompletedOlder Adult Effectiveness of 2 Treatments
Dental Caries
N/A2019-09-18
CompletedDiabetes Inspired Culinary Education
Type I Diabetes
EARLY_Phase 12019-09-05
CompletedTailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With
Stress, Carer Stress Syndrome, Dementia
N/A2019-08-29
Active Not RecruitingOptimization of NIBS for Diabetic Neuropathy Neuropathic Pain
Diabetic Neuropathies, Chronic Pain
N/A2019-06-06
Active Not RecruitingEffects of Semaglutide in HIV-Associated Lipohypertrophy
HIV/AIDS, Lipohypertrophy, Obesity
Phase 22019-05-16
TerminatedHIV Reservoir Reduction With Interleukin-2
HIV Infection
Phase 22019-04-01
CompletedFatigue Management Programs for People With MS
Multiple Sclerosis
N/A2019-03-01
CompletedA COmmunity and Tech-Based ApproaCh for Hypertension Self-MANagement
Hypertension, Self-management, Technology
N/A2019-03-01
CompletedTRANSLATE: Transgender and Gender Nonconforming Individuals' Access to Healthcare
Gender Identity
N/A2019-02-01
CompletedProject 2 Airway Potential Hydrogen (pH) in Asthma
Cystic Fibrosis, Asthma, Severe Persistent Asthma
Phase 1 / Phase 22018-11-01
CompletedTechnology-based Intervention and Positive Psychological Training for Blood Pressure Control in African Americ
Hypertension, Self-management, Technology
N/A2018-10-25
CompletedTesting TRUST Depression Management Intervention
Depressive Symptoms, Quality of Life
N/A2018-10-01
CompletedMeasuring Brain Activity of School Age Children
Perinatal Hypoxia, Dopamine, Neurobehavioral Manifestations
2018-06-08
RecruitingEvaluation of an Advanced Lower Extremity Neuroprostheses
Spinal Cord Injuries, Stroke, Paralysis
N/A2018-06-01
CompletedEfavirenz for Patients With Alzheimer's Disease
Alzheimer Disease, Early Onset
Phase 12018-05-05
CompletedProviders Against Cavities in Children's Teeth
Dental Caries
N/A2017-11-15
CompletedPartnering Physical and Emotional Fitness: Improving Cardiac Recovery With Training in Emotion Regulation
Cardiac Disease, Myocardial Infarction
N/A2017-10-11
CompletedNeuroimaging During Pure Oxygen Breathing
Hyperoxia, Hypoxia, Brain, Neurobehavioral Manifestations
Phase 42017-10-02
CompletedThe Grandmother Study: Grandmother Initiatives in Family Transformation
Women, Grandmother
N/A2017-08-01
CompletedTailored Health Self-Management Interventions for Highly Distressed Family Caregivers
Distress, Caregiver
N/A2017-06-12
CompletedMedication Adherence in Hypertensive Individuals With Bipolar Disorder
Hypertension, Bipolar Disorder
N/A2017-03-13
CompletedUsing a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals
Smoking, Tobacco Dependence
N/A2016-08-01
CompletedSelf-Management Behaviors of Caregivers of the Chronically Critically Ill
Critical Illness
N/A2016-02-01
TerminatedOrgan Donation Interventions Among High Students
Tissue and Organ Procurement, Adolescent Behavior, Communication
N/A2015-10-01
CompletedBuilding Resilience After Childhood Emergencies (BRACE)
Posttraumatic Stress Disorder
N/A2015-10-01
CompletedDecision Support Among Surrogate Decision Makers of the Chronically Critically Ill (INVOLVE)
Critical Illness
N/A2015-09-01
CompletedFamily Access to Dentist Study
Dental Caries
N/A2015-08-01
CompletedDirect Comparison of Spinal Cord Stimulator Parameter Settings
Spinal Cord Stimulation, High-frequency Stimulation, High-density Stimulation
N/A2015-06-01
CompletedMindfulness Attitude to Deliver Dietary Approach to Stop Hypertension
Prehypertension
N/A2015-06-01
CompletedHandheld Mirror to Improve Child's Behavior During Dental Treatment
Behavior
N/A2015-05-01
TerminatedHelium-oxygen Gas Mixtures Delivered by a High Flow Nasal Cannula in Bronchiolitis
Bronchiolitis, Heliox, Pediatrics
N/A2014-12-01
CompletedA Clinical Trial of SystemCHANGE to Improve Exercise, Diet and Health in HIV-Infected Adults
HIV, Cardiovascular Disease
N/A2014-11-01
CompletedSelf-management for People With Epilepsy and a History of Negative Health Events
Epilepsy
N/A2014-09-01
CompletedAIDS 347: IL-6 Blockade in Treated HIV Infection
HIV Infections
Phase 1 / Phase 22014-08-01
CompletedChlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Surgical Site Infection
N/A2014-03-01
Completede-Mobile Tablet for People With Chronic Conditions
Fibromyalgia, Multiple Sclerosis, Osteoarthritis
N/A2013-11-01
CompletedUniversity Student Intervention to Increase Organ Donation
Organ Donation, Health Behavior
N/A2013-10-01
CompletedTargeted Self-Management for Epilepsy and Serious Mental Illness (TIME)
Epilepsy, Schizophrenia, Schizoaffective Disorder
N/A2013-09-01
CompletedRandomized Trial of an HIV Navigation Program for Early Palliative Care
HIV, Chronic Disease
Phase 22013-06-01
CompletedHome or Office Visit for the Insertion of Implantable Birth Control
Contraception
N/A2013-06-01
CompletedHealth Promotion and Wellness Program for Adults With Disabling Conditions
Stroke, Multiple Sclerosis, Rheumatoid Arthritis
N/A2013-01-01
CompletedWheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy
Wheezing, Allergy
Phase 42013-01-01
CompletedPatient and Physician Intervention to Increase Organ Donation
Tissue and Organ Donation, Communication
N/A2012-09-01
CompletedTargeted Management Intervention for African-American Men With TIA or Stroke
Stroke, Transient Ischemic Attack (TIA)
N/A2012-05-01
CompletedCornea Preservation Time Study
Cornea Preservation Time, Endothelial Keratoplasty, Transplant Success
Phase 42012-04-16
CompletedTreatment Adherence Enhancement in Bipolar Disorder
Treatment Noncompliance, Bipolar Disorder
N/A2012-04-01
WithdrawnPharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis
Cystic Fibrosis, Methicillin-resistant Staphylococcus Aureus
Phase 12012-01-01
CompletedExamining the Effects of a Telehealth Self-management Intervention in Multiple Sclerosis
Multiple Sclerosis
N/A2011-07-01
CompletedImproving Outcomes for Individuals With Serious Mental Illness and Diabetes
Diabetes Mellitus, Bipolar Disorder, Depression
N/A2011-07-01
CompletedNonvisual Foot Examination for People With Diabetes and Visual Impairment
Diabetes, Visual Impairment
N/A2011-07-01
CompletedPromoting Physical Activity Behavior in Persons With Multiple Sclerosis
Multiple Sclerosis
N/A2011-07-01
CompletedOptimizing Posttraumatic Stress Disorder Treatment: Prolonged Exposure (PE) Versus PE Plus Sertraline
Posttraumatic Stress Disorder
Phase 32011-03-01
CompletedIdeas Moving Parents and Adolescents to Change Together (IMPACT)
Overweight, Obese
N/A2011-02-01
CompletedElectronic Self-management Resource Training for Mental Health
Depression, Generalized Anxiety Disorder
N/A2011-02-01
CompletedStudy of SystemCHANGE-HIV
HIV
N/A2011-01-01
CompletedCancer Prevention and Care Among Aged
Cancer
N/A2011-01-01
CompletedUse of Sterile Water Feeds for Treatment of Hypernatremia in Extremely Low Birth Weight Infants
Extremely Low Birth Weight Infants, Hypernatremia
N/A2010-11-01
CompletedNonvisual Foot Inspection for People With Visual Impairment
Diabetes, Visual Impairment
N/A2010-09-01
CompletedEnhancing Teachable Moment Communication for Smoking Cessation and Weight Management
Clinician Patient Communication, Smoking Cessation, Weight Management
N/A2010-07-01
CompletedLactobacillus Reuteri in the Prevention of Antibiotic Associated-diarrhea and Clostridium Difficile
Antibiotic-associated Diarrhea, Clostridium Difficile
N/A2010-05-01
TerminatedInterpreters as Advocates for Hypertensive Patients
Hypertension
N/A2010-04-01
CompletedImproving Urinary Continence and Quality of Life in Prostate Cancer Patients
Urinary Incontinence
N/A2010-01-01
CompletedInterstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
2009-09-01
CompletedDose of Early Therapeutic Mobility: Does Type or Frequency Matter?
Critical Illness
N/A2009-05-01
CompletedCommunity Trial to Enhance Organ Donation
Tissue and Organ Procurement, Health Behavior
N/A2009-03-01
CompletedInterferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected Children
Tuberculosis, HIV
2009-01-26
CompletedTransplant Navigator Intervention to Overcome Barriers to Kidney Transplantation
End Stage Renal Disease
N/A2009-01-01
CompletedA Trial of Vitamin D Therapy in Patients With Heart Failure
Heart Failure
N/A2008-07-01
CompletedCustomized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
Bipolar Disorder
N/A2008-07-01
CompletedPersonal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients
Bipolar Disorder
2008-04-01
CompletedPortable Monitoring for Diagnosis and Management of Sleep Apnea
Sleep Apnea, Obstructive
N/A2008-02-01
CompletedDiagnosis of Tuberculosis Infection in HIV Co-infected Children
Latent Tuberculosis Infection, Tuberculosis, HIV Infections
2008-01-15
CompletedA Trial of Telemonitoring in Adults With Heart Failure
Heart Failure
N/A2007-11-01
CompletedXylitol for Caries Prevention in Inner-City Children
Dental Caries
N/A2007-08-01
CompletedAnalyzing Genes That May Increase the Risk of Developing High Blood Pressure
Hypertension
2007-08-01
CompletedPentoxifylline in Patients With Nonalcoholic Steatohepatitis
Nonalcoholic Steatohepatitis
Phase 22006-12-01
CompletedEfficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
N/A2006-09-01
CompletedLong-term Exercise in Older Cardiac Patients
Coronary Artery Disease
N/A2006-04-01
CompletedSafety and Efficacy of Autologous, Intracoronary Stem Cell Injections in Total Coronary Artery Occlusions
Coronary Occlusion
Phase 12006-01-01
CompletedIntensive Communication for Chronically Critically Ill
Critical Care
N/A2005-11-01
RecruitingGenetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Barrett's Esophagus, Esophageal Neoplasm
2005-10-01
CompletedCross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus
Nystagmus
N/A2005-02-01
CompletedComparison of Two Treatments for Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Phase 32004-09-01
CompletedHuman Immunity to MSP-1 in Western Kenya
Plasmodium Falciparum Malaria
2004-07-01
CompletedUnderstanding Treatment Adherence Among Individuals With Rapid Cycling Bipolar Disorder
Bipolar Disorder
2004-07-01
CompletedDefining an Obesity QTL on Chromosome 3q
Cardiovascular Diseases, Heart Diseases, Obesity
2004-07-01
CompletedUnderstanding Treatment Adherence Among Individuals With Bipolar Disorder
Bipolar Disorder
2004-03-01
CompletedKangaroo Care and Premature Infant Sleep
Premature Birth of Newborn
N/A2003-01-01
CompletedOvercoming Nutritional Barriers in Hemodialysis Patients
End Stage Renal Disease
N/A2002-02-01
CompletedEnhancing Treatment Adherence in Pediatric Asthma With a Problem Solving Intervention
Asthma
N/A2001-01-22
CompletedAbbreviated MgSO4 Therapy in Post-partum Preeclampsia
Pregnancy, Preeclampsia
N/A2001-01-01
CompletedStudy of an Implantable Functional Neuromuscular Stimulation System for Patients With Spinal Cord Injuries
Spinal Cord Injury
N/A1996-09-01
TerminatedStudy of Combined Intercostal and Diaphragm Pacing for Artificial Respiration in Quadriplegic Patients
Quadriplegia
N/A1991-05-01
CompletedChelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
Anemia (Iron-Loading), Beta-Thalassemia, Hematologic Diseases
Phase 21989-06-05