NCT01125436

A Trial of Vitamin D Therapy in Patients With Heart Failure

A Randomized Placebo Controlled Trial of Vitamin D Therapy in Patients With Heart Failure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Case Western Reserve University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if vitamin D will improve physical performance in older adults with heart failure.

Detailed description

The study is designed as a short pilot study which will assess safety and efficacy of high dose Vitamin D therapy in a heart failure population. A 6 month randomized double blind placebo-controlled trial of 50,000 units of oral vitamin D3(cholecalciferol) weekly plus 800 calcium daily vs. weekly placebo plus 800 calcium alone in 64 heart failure (HF) patients \> 50 years old. This design was chosen over a cross-over design due to the long wash-out period for vitamin D.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cholecalciferol	50,000 units of oral vitamin D3(cholecalciferol) weekly plus 800 calcium daily
DIETARY_SUPPLEMENT	Cholecalciferol	Weekly placebo plus 800 calcium alone

Timeline

• Start date: 2008-07-01
• Primary completion: 2011-09-01
• Completion: 2011-09-01
• First posted: 2010-05-18
• Last updated: 2022-08-10
• Results posted: 2022-08-10

Locations

1 site across 1 country: United States