Trials / Conditions / Substance-Related Disorders

Substance-Related Disorders

339 registered clinical trials studyying Substance-Related Disorders — 29 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	SMART-r: Substance Monitoring and Active Relapse Tracking Repository NCT06676059	National Institute on Drug Abuse (NIDA)	—
Not Yet Recruiting	Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL) NCT07520617	University Hospital, Clermont-Ferrand	N/A
Recruiting	Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families NCT07365293	Chestnut Health Systems	N/A
Not Yet Recruiting	Prevention of Relapse in Behavioral Disorders NCT07052175	Clínica Nuestra Señora de la Paz	N/A
Recruiting	Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years NCT05910580	Emory University	N/A
Not Yet Recruiting	Development of the Drug and Alcohol Respiratory Health Test NCT06921278	King's College London	—
Active Not Recruiting	Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary NCT06810076	University of Pittsburgh	N/A
Recruiting	Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction NCT06916754	Beykoz University	N/A
Recruiting	Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits NCT06387290	University of Utah	Phase 3
Recruiting	Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Ove NCT06852170	Chestnut Health Systems	N/A
Recruiting	GLP-1R Agonist Treatment for Opioid Use Disorder NCT06548490	Milton S. Hershey Medical Center	Phase 2
Recruiting	Understanding the Role of Doulas in Supporting People With PMADs NCT05763537	University of Montana	N/A
Recruiting	Phase II: Scalable Digital Delivery of CRAFT Training for Professionals to Maximize Treatment Rates of OUD in NCT06685003	We The Village, Inc.	N/A
Active Not Recruiting	Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) NCT06023459	Yih-Ing Hser	Phase 3
Recruiting	Feasibility of the 5-Step Method in the U.S. NCT06565429	Villanova University	N/A
Terminated	Mobile Technologies Extending Reach of Primary Care for Substance Use Disorders NCT06208839	Chess Mobile Health	N/A
Completed	Validation of the Behavioral Activation for Depression Scale in Individuals With Substance Use Disorders NCT07395700	Lauro Gutiérrez Castro	—
Completed	Evaluating Feasibility, Acceptability, Usability, and an Initial Estimate of Effect of a Novel Training Platfo NCT07090590	Thrive Digital Health, LLC	N/A
Enrolling By Invitation	Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder NCT06415994	Indiana University	—
Recruiting	CMAP Plus Intervention for Self-harm in Individuals with Substance Use Disorder in Pakistan NCT05476601	Pakistan Institute of Living and Learning	N/A
Recruiting	Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program NCT06236100	RTI International	N/A
Recruiting	Disrupting SRFOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions NCT06560866	Chestnut Health Systems	N/A
Recruiting	The Road to Recovery Initiative (R2RI) NCT06639373	BC Centre on Substance Use	—
Enrolling By Invitation	Fatal Overdose Review Teams - Research to Enhance Surveillance Systems NCT06084221	Indiana University	N/A
Recruiting	Transdermal Rotigotine as Adjunct to Behavioral Therapy for Cocaine Use Disorder NCT05886582	Virginia Commonwealth University	Phase 2
Recruiting	First Face Training Evaluation in Tribal Communities NCT05998005	Cambridge Health Alliance	N/A
Active Not Recruiting	Maternal Brain Imaging in Opioid Use Disorder NCT06008990	Indiana University	—
Recruiting	Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention NCT05973838	University of Maryland, College Park	N/A
Completed	Reducing Drug Use in Justice-Involved Emerging Adults NCT05834881	Chestnut Health Systems	N/A
Completed	Scalable Digital Delivery of Evidence-based Training for Professionals to Maximize Treatment Rates of OUD in F NCT05875142	We The Village, Inc.	N/A
Active Not Recruiting	Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder NCT05322954	University of Wisconsin, Madison	Phase 1
Recruiting	Whole Health in VA Mental Health: Omnis Salutis NCT05400252	VA Office of Research and Development	N/A
Unknown	Validation of the Cannabis Abuse Screening Test in General Practice(GP-CAST) NCT05633043	University Hospital, Clermont-Ferrand	—
Active Not Recruiting	Scalable Digital Delivery of Evidence-based Training for Family to Maximize Treatment Admission Rates of Opioi NCT05666856	We The Village, Inc.	N/A
Active Not Recruiting	Socializing a Science-Based Digital Therapeutic for Substance Use Disorders NCT05648786	Square2 Systems, Inc.	N/A
Completed	Multifamily Group Psychoeducation for SUD's in Turkey NCT05564559	Ege University	N/A
Completed	Data-driven Identification for Substance Misuse NCT03833804	University of Wisconsin, Madison	N/A
Recruiting	CRP and S&A for Inpatient Veterans NCT05054738	VA Office of Research and Development	N/A
Recruiting	Expression of Stress Markers During Meth Treatment (EXPRESS+) NCT05558345	University of California, Los Angeles	N/A
Withdrawn	Trauma-Focused Intervention With Women Experiencing Homelessness NCT05873517	Rush University Medical Center	Phase 1
Completed	Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa NCT05282173	University of Maryland, College Park	N/A
Completed	Effectiveness of a Training Program for Self-management of the Substance Addiction Consequences - a Study Prot NCT05397925	Nursing School of Lisbon	N/A
Unknown	Housing for Recovery Initiative NCT05341830	Adrienne Sabety	N/A
Completed	Effect of Fruit Smoothie Supplementation on Psychological Distress Among People Receiving Opioid Agonist Thera NCT05229770	Haukeland University Hospital	N/A
Active Not Recruiting	Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco NCT05290025	Haukeland University Hospital	N/A
Completed	Integrated Exercise Program in Opioid Agonist Therapy Clinics NCT05242848	Haukeland University Hospital	N/A
Completed	Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence NCT05299515	University of Maryland, College Park	N/A
Completed	Feasibility and Effects of Activity Trackers Among Alcohol Users Receiving In-patient Treatment for Alcohol Us NCT06629493	University of Oviedo	N/A
Recruiting	Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment NCT05489068	University of New Mexico	N/A
Completed	Feasibility and Acceptability Study of the "O'Dide" Application in People Suffering From an Addiction NCT04659954	University Hospital, Toulouse	N/A
Active Not Recruiting	Impact of Work Activity on SUD Outcomes NCT04969081	VA Office of Research and Development	N/A
Completed	Preventing Impaired Driving Among Adolescents NCT04959461	Stanford University	N/A
Completed	Mental Health in Latin American Countries With Different Economic Incomes During the Covid-19 Pandemic. NCT05060445	Universidad Westhill, Facultad de Psicología	—
Completed	Anxiety, Depression and Substance Use in Undergraduate Health Science Students During the Covid-19 Pandemic. NCT05075629	Universidad Westhill, Facultad de Psicología	—
Withdrawn	An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder NCT04157062	West Virginia University	N/A
Completed	Benzodiazepines in Opiate Replacement Therapy NCT04622995	University of Stirling	—
Suspended	Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression NCT04934553	Charles Taylor	N/A
Unknown	Addiction in Intensive Cardiac Care Units NCT05063097	Assistance Publique - Hôpitaux de Paris	—
Unknown	Transcranial Direct Current Stimulation on Inhibitory Control in Addictions. NCT05350033	Universidad de Almeria	N/A
Completed	Resonance Breathing Intervention Opioid Use Disorder NCT05830773	University of Texas at Austin	N/A
Completed	Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Car NCT05907174	University of Maryland, College Park	N/A
Terminated	Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation NCT04228276	VA Office of Research and Development	N/A
Recruiting	Alcohol, Psychoactive Drugs, Analgesics and Evaluation in Penetrating Abdominal Trauma NCT07330349	Fundacion Clinica Valle del Lili	—
Completed	Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes NCT04637581	Dartmouth-Hitchcock Medical Center	N/A
Completed	Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders NCT04556552	Emory University	Phase 3
Completed	Neuroimaging and CBD for Opioid Use Disorder NCT04567784	Yasmin Hurd	Phase 2
Completed	Incentives to Decrease Opioid Use - Pilot NCT04235582	Wake Forest University Health Sciences	N/A
Completed	Addictology Expert Patients' Fields of Intervention NCT04458987	Assistance Publique - Hôpitaux de Paris	N/A
Unknown	Quality of Life and Addiction Among Hospital Night Workers NCT04291534	University Paris 7 - Denis Diderot	—
Enrolling By Invitation	Alliances to Disseminate Addiction Prevention and Treatment (ADAPT) NCT04499079	Indiana University	N/A
Completed	EffectS of CAnnabidiol in Patients: Evaluation NCT04405414	Nantes University Hospital	—
Suspended	Cognitive Rehabilitation for Opioid Abuse-related Cognitive Impairment NCT04404348	Oklahoma State University Center for Health Sciences	N/A
Recruiting	Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use Disorder NCT04141202	St. Olavs Hospital	—
Completed	Neuroimmune Dysfunction in Alcohol Use Disorder NCT04210713	University of Maryland, Baltimore	Phase 1
Completed	We The Village Family Support Study NCT04250077	We The Village, Inc.	N/A
Completed	Increasing Linkage to Family Planning Care for Individuals With Substance Use Disorder NCT04162184	Denver Health and Hospital Authority	N/A
Completed	Phone App for Grounding NCT03258905	Treatment Innovations	Phase 2
Completed	Evaluation of the Efficacy of the Individually Adjusted Therapy Scale (ATI) on the Addiction Severity NCT03606759	University Hospital, Bordeaux	N/A
Completed	Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop NCT03868930	VA Office of Research and Development	N/A
Completed	Encouraging Judicious Prescribing of Opioids in Los Angeles County NCT03856593	University of Southern California	N/A
Completed	Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students NCT03925220	Tufts University	N/A
Unknown	Growing Together: Women in Opioid Treatment and Their Infants NCT03866694	Boston University Charles River Campus	N/A
Completed	COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM NCT03306173	Virginia Polytechnic Institute and State University	N/A
Completed	Increasing MSM in the Continuum of Care in Kazakhstan NCT02786615	Columbia University	N/A
Unknown	Computerized Exercise to Alter Stimulant Approach Responses NCT03902405	University of British Columbia	N/A
Completed	Behavioral Activation for Heroin Use in China: A Randomized Controlled Trial NCT03705143	University of North Carolina, Chapel Hill	N/A
Withdrawn	Methylphenidate for Cocaine Dependence NCT03090269	ANRS, Emerging Infectious Diseases	Phase 2
Terminated	Effects of Repeated Memory Training on Memory Function and Addiction Related Processes NCT03285256	Johns Hopkins University	N/A
Unknown	French Validation of the Dual Diagnosis Screening Interview (F_DDSI) NCT03585842	University Hospital, Clermont-Ferrand	—
Completed	Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study NCT03414411	Boston University	—
Completed	Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study NCT03339024	Norwegian University of Science and Technology	Phase 3
Completed	Preventing Addiction Related Suicide (PARS) NCT03166709	University of Washington	N/A
Completed	Behavioral Economic Purchasing Decisions for Cigarettes of Varied Compositions NCT02888249	Johns Hopkins University	N/A
Completed	Development of a Patient Centered Mental Health Intervention for Recent Veterans NCT02943408	VA Office of Research and Development	N/A
Completed	Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults NCT03944954	Michael J. Wesley, PhD	EARLY_Phase 1
Active Not Recruiting	Medication Misuse and Dependence Among Elderly NCT03162081	University Hospital, Akershus	—
Unknown	Integrated Prevention and Collaborative Care for Youth Mental Health NCT03114007	St. Justine's Hospital	N/A
Unknown	Peer MI for Substance-using Emerging Adults NCT03264872	University of Illinois at Urbana-Champaign	Phase 2
Completed	Behavioral Insights to Encourage Judicious Prescribing of Opioids NCT02790476	University of Southern California	N/A
Completed	Women's Initiative Supporting Health Increasing Healthcare Access NCT02964845	University of Rochester	N/A
Completed	Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace NCT02951143	Virginia Polytechnic Institute and State University	N/A
Completed	Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3 NCT03048552	New York State Psychiatric Institute	N/A
Completed	Oxytocin and Alcohol Withdrawal and Dependence NCT02903251	Norwegian University of Science and Technology	Phase 3
Unknown	The Development and Evaluation of the Ho'Ouna Pono Drug Prevention Curriculum NCT03119129	Hawaii Pacific University	N/A
Completed	Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation NCT02907944	Yale University	N/A
Completed	A Text Messaging Program to Help Prevent Early Opioid Relapse NCT02846649	University of Pittsburgh	N/A
Completed	Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD NCT02755103	Medical University of South Carolina	N/A
Completed	Conflict Between Maternal Autonomy and Child Health in Substance-use NCT02797990	London School of Hygiene and Tropical Medicine	—
Completed	HIV & Drug Abuse Prevention for South African Men NCT02358226	University of California, Los Angeles	Phase 3
Completed	A Bundled Rapid HIV/HCV Testing Intervention to Increase Receipt of Test Results NCT02355080	Columbia University	Phase 2 / Phase 3
Completed	Treatment Engagement With Technology-assisted Treatment NCT02674477	Johns Hopkins University	N/A
Completed	Study of Structural Imaging NCT02564991	National Institute on Alcohol Abuse and Alcoholism (NIAAA)	—
Completed	Adolescent Mental Health InSciEd Out NCT02680899	Mayo Clinic	N/A
Completed	Technology Enhanced Behavioral Activation Treatment for Substance Use NCT02707887	University of North Carolina, Chapel Hill	N/A
Completed	Alcohol, Behavior, and Brain Imaging NCT03930446	University of Chicago	EARLY_Phase 1
Completed	Interactions Between Drug Effects and Environments II NCT03075501	University of Illinois at Chicago	Phase 4
Completed	Women's Treatment and Early Recovery NCT02977988	University of Southern California	N/A
Unknown	Brain Electrophysiological Study(EEG/ERP) on Opiate Addicts Treating by Bilateral NAc/ALIC Deep Brain Stimulat NCT02594306	Tang-Du Hospital	N/A
Completed	Treatment Adherence in Substance Users NCT02930577	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	—
Completed	A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity NCT02655354	University of Washington	N/A
Completed	Group Motivational Interviewing (GMI) For Homeless Veterans In VA Services NCT02233738	VA Office of Research and Development	N/A
Completed	Exercise and Treatment-as-usual in Substance Use Treatment Outcomes NCT02570360	University of Wisconsin, Madison	N/A
Completed	Helping College Students With ADHD Lead Healthier Lifestyles NCT02829970	University of Maryland, College Park	N/A
Completed	Buprenorphine to Improve HIV Care Engagement and Outcomes NCT01936857	Oregon Health and Science University	Phase 4
Completed	Intervening to Reduce Suicide Risk in Veterans With Substance Use Disorders NCT02439762	University of Michigan	N/A
Completed	Telephone Reminder to Increase Appointment Rates NCT04707599	Sorlandet Hospital HF	N/A
Terminated	Abuse Liability of Pregabalin and Its Effects on Benzodiazepine Withdrawal Symptoms NCT02423018	Centre for Addiction and Mental Health	Phase 4
Completed	Mindfulness-Based Relapse Prevention for Methadone Maintenance NCT03882125	Pacific University	N/A
Completed	A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot NCT02335125	University of Washington	N/A
Completed	Collaborative Care From the ED for Trauma Patients With Prescription Drug Misuse NCT02804295	University of Washington	N/A
Completed	Yoga Intervention for Substance Use and ART Adherence in Community Reentry NCT02492893	University of Pennsylvania	N/A
Completed	PHAST: Physical Activity in Substitution Therapy NCT02309021	University Hospital, Basel, Switzerland	N/A
Completed	Implementation and Evaluation of a Family-based Intervention Program for Children of Mentally Ill Parents NCT02308462	Silke Wiegand-Grefe, Prof. Dr.	N/A
Completed	Adherence to Polypharmacy in Patients With Opioid Substitution Therapy Using Electronics NCT02701660	University Hospital, Basel, Switzerland	N/A
Completed	Arise: An Online Relapse Prevention Tool for Adolescent Substance Abusers NCT02715557	3-C Institute for Social Development	N/A
Completed	Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life NCT02945371	University of Oregon	N/A
Completed	The Computer-based Drug and Alcohol Training Assessment in Kenya NCT02388243	Africa Institute of Mental and Brain Health (AFRIMEB)	N/A
Completed	Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment NCT02125539	Inflexxion, Inc.	Phase 2
Unknown	Prevention of Drug Use in Adolescence: Intervening in Parenting Styles NCT02386280	Federal University of Health Science of Porto Alegre	Phase 1 / Phase 2
Completed	Abuse Liability of Controlled-Release Oxycodone Formulations NCT02101840	Centre for Addiction and Mental Health	Phase 4
Completed	Optimizing Behavioral Health Homes for Adults With Serious Mental Illness NCT02318797	University of Pittsburgh	N/A
Completed	Screening, Brief Intervention, and Referral to Treatment in Primary Care NCT01966432	Duke University	N/A
Completed	SET-Recovery/Healthy Home NCT02702193	University of Miami	N/A
Completed	Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders NCT01690494	Columbia University	N/A
Completed	Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence NCT01984177	Centre for Addiction and Mental Health	—
Completed	Project CHOICE: Efficacy Testing of CHOICE and CHOICE+Normative Feedback Interventions NCT02083523	University of Illinois at Urbana-Champaign	Phase 1
Completed	Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients NCT01671501	University of California, San Francisco	N/A
Completed	Influence of Bupropion on the Effects of MDMA NCT01771874	University Hospital, Basel, Switzerland	Phase 1
Completed	Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort NCT01740115	Boston Medical Center	—
Completed	MISSION-Vet HUD-VASH Implementation Study NCT01430741	VA Office of Research and Development	N/A
Completed	Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution NCT01560221	Johns Hopkins University	Phase 1
Completed	Performance-based Reinforcement to Enhance Cognitive Remediation Therapy NCT01633138	Yale University	N/A
Completed	The Co-Venture Trial: A Cluster Randomized Trial of Personality-targeted Interventions on Adolescent Substance NCT01655615	St. Justine's Hospital	N/A
Completed	The Effect of Muscular Strength Training in Patients With Drug Addiction NCT02218970	Norwegian University of Science and Technology	N/A
Completed	The Effect of Aerobic Endurance Training in Patients With Drug Addiction NCT02017821	Norwegian University of Science and Technology	N/A
Completed	Family and Adolescent Motivational Incentives for Leveraging Youth NCT01736995	Oregon Research Institute	N/A
Completed	Preventing Violence Among Veterans in Substance Use Disorder Treatment NCT01337973	VA Office of Research and Development	N/A
Completed	Motivational Assessment Program to Initiate Treatment NCT01891656	University of North Texas Health Science Center	N/A
Completed	Clinical Monitoring to Facilitate Continuous Care for Substance Abusing Clients NCT01831999	Treatment Research Institute	N/A
Completed	Pre-Release VIVITROL for Opioid Dependent Inmates NCT01563718	Rhode Island Hospital	Phase 4
Completed	Brief Intervention for Substance Use and Partner Abuse Among Females in the ER NCT01709552	Rhode Island Hospital	N/A
Completed	Family Therapy Via Video Teleconference for Substance-Abusing Rural Adolescents NCT01751217	Oregon Research Institute	N/A
Completed	Stopping Benzodiazepines and Related Molecules Among Elderly Living in Residential Institutions NCT02715440	Assistance Publique - Hôpitaux de Paris	N/A
Completed	"Effectiveness of a Brief Intervention for Substances Consumption Linked to the Alcohol, Smoking and Substance NCT01573416	Pontificia Universidad Catolica de Chile	Phase 3
Completed	A Prenatal Mentalization-focused 4D Ultrasound and a Pregnancy Diary Intervention for Substance-abusing Women NCT03413631	Turku University Hospital	N/A
Unknown	Screening for Youth Alcohol and Drug Use: A Study of Primary Care Providers NCT02408952	Kaiser Permanente	N/A
Completed	Screening to Augment Referral to Treatment- Project START NCT01539525	Yale University	N/A
Completed	Home-Based Program to Help Parents of Drug Abusing Adolescents NCT01591239	Treatment Research Institute	N/A
Completed	Behavioral Treatment for Substance Abuse NCT01438346	University of Utah	N/A
Completed	Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA) NCT01386177	University Hospital, Basel, Switzerland	Phase 1
Completed	DOX as a Potential Treatment for Methamphetamine Dependence NCT02785393	Baylor College of Medicine	Phase 1
Completed	Integrated Cognitive Behavioral Therapy (ICBT) for Posttraumatic Stress Disorder (PTSD) and Substance Use Diso NCT01457404	Dartmouth-Hitchcock Medical Center	Phase 3
Unknown	Mental Health Related to School Dropout in Luxembourg NCT01354236	Public Research Centre Health, Luxembourg	—
Completed	Family Training Program for Parents of Substance Using Adolescents NCT01344382	Treatment Research Institute	Phase 1 / Phase 2
Completed	Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA) NCT01270672	University Hospital, Basel, Switzerland	N/A
Completed	Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment NCT01457391	Dartmouth-Hitchcock Medical Center	Phase 3
Completed	Functional Magnetic Resonance Imaging of Opioid Withdrawal in Healthy Human Volunteers NCT01006707	Stanford University	N/A
Completed	Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Ab NCT01414907	Skane University Hospital	N/A
Completed	Motivational Interviewing to Reduce Substance Use Among Depression Patients NCT02420561	University of California, San Francisco	N/A
Withdrawn	A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People NCT01224002	National Institute of Dental and Craniofacial Research (NIDCR)	—
Completed	Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA) NCT01136278	University Hospital, Basel, Switzerland	Phase 1
Completed	Validating Interventions for Diverse Adolescents NCT01018654	University of Utah	Phase 2
Completed	Developing an Intervention to Address Suicide Risk During Substance Use Disorder NCT01127932	University of Michigan	N/A
Completed	Computer-Based Training in Cognitive Behavior Therapy (CBT4CBT) NCT01406899	VA Connecticut Healthcare System	Phase 1
Completed	Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults NCT01046539	National Institute on Drug Abuse (NIDA)	Phase 1
Completed	Intervention for Veterans With Depression, Substance Disorder, and Trauma NCT00958217	VA Office of Research and Development	N/A
Completed	Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) NCT00990067	University Hospital, Basel, Switzerland	Phase 1
Completed	Ostrobothnia Depression Study (ODS). A Naturalistic Follow-up Study on Depression and Related Substance Use Di NCT02520271	Seinajoki Central Hospital	N/A
Withdrawn	Primary Care iSBIRT to Reduce Serious Teen Health Risks NCT00891631	Boston Children's Hospital	Phase 1 / Phase 2
Completed	Smoking Cessation Treatment for Methadone Maintenance Patients NCT01027754	Albert Einstein College of Medicine	Phase 4
Unknown	Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders NCT00957775	National Development and Research Institutes, Inc.	N/A
Completed	Research on Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders NCT01117753	Medical University of South Carolina	Phase 2
Completed	Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokineti NCT00886886	University Hospital, Basel, Switzerland	Phase 1
Completed	Brief Intervention in Primary Care for Problem Drug Use and Abuse NCT00877331	University of Washington	N/A
Completed	Partner-Specific HIV Risk Reduction Intervention for Drug-Using Adolescents NCT00831883	Women and Infants Hospital of Rhode Island	N/A
Completed	Treating Violence-Prone Substance Use Disorder Patients NCT00700973	US Department of Veterans Affairs	Phase 2 / Phase 3
Completed	Rapid HIV Testing and Counseling in Drug Abuse Treatment NCT00809445	University of Miami	Phase 3
Completed	Relapse Prevention With Varenicline NCT00944554	Johns Hopkins University	Phase 4
Completed	Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD) NCT01365247	The City College of New York	N/A
Completed	Dual-Diagnosis and Compulsory Treatment NCT00970372	Sorlandet Hospital HF	—
Completed	Women's Recovery Group (WRG) Study - A Randomized Controlled Stage II Trial NCT01318538	Mclean Hospital	N/A
Completed	Combined Treatment for Patients With Comorbid Substance Use Disorders and Post-traumatic Stress Disorder (PTSD NCT00763542	VU University of Amsterdam	Phase 2
Completed	Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal NCT00661674	Stanford University	N/A
Completed	Contingency Management for Cocaine Dependence: Cash Versus Vouchers NCT01366716	Treatment Research Institute	N/A
Completed	Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Off NCT00690352	University of Nebraska	—
Completed	Mentored Clinical Career Award in Adolescent Substance Abuse NCT00622219	Boston Children's Hospital	N/A
Unknown	Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers NCT00726960	Karolinska University Hospital	Phase 1
Completed	Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental NCT00419029	San Francisco Veterans Affairs Medical Center	N/A
Terminated	Pilot Study Examining Effect for Dextroamphetamine to Treat Cocaine Dependence Plus Attention-deficit Hyperact NCT00514202	The University of Texas Health Science Center, Houston	Phase 2
Completed	HIV Prevention Among Vulnerable Male Youth NCT01771237	Ann & Robert H Lurie Children's Hospital of Chicago	N/A
Unknown	Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone NCT00504413	University of Washington	Phase 1
Completed	Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment NCT01456338	Dartmouth-Hitchcock Medical Center	Phase 2
Terminated	Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use NCT00430573	Boston University Charles River Campus	Phase 2
Completed	Medical Office Intervention for Adolescent Drug Use - Attention Study Supplement NCT00593034	Boston Children's Hospital	—
Completed	Multi-Level HIV Prevention for Pregnant Drug Abusers NCT01976702	National Institute on Drug Abuse (NIDA)	N/A
Completed	STD Risk Reduction for Heterosexual Methamphetamine Users NCT00344214	University of California, San Diego	N/A
Completed	First Episode Schizophrenia and Cannabis-Related Disorder Study NCT00573287	Dartmouth-Hitchcock Medical Center	N/A
Completed	Combined Treatment for Alcohol-Dependent Individuals With PTSD NCT00262223	New York State Psychiatric Institute	Phase 2
Completed	Rivastigmine For Methamphetamine Dependent Individuals NCT00158210	National Institute on Drug Abuse (NIDA)	Phase 1
Completed	Prescription Opioid Addiction Treatment Study (POATS) NCT00316277	Mclean Hospital	Phase 3
Completed	Impaired Decision-making in Adolescents NCT01253993	UMC Utrecht	—
Completed	Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulan NCT00248092	New River Pharmaceuticals	Phase 1 / Phase 2
Completed	Screening and Brief Advice to Reduce Teen Substance Use NCT00227877	Boston Children's Hospital	N/A
Completed	Brief Intervention for Prescription Drug Misuse in General Hospital NCT00514839	University of Luebeck	Phase 2
Completed	Buprenorphine and Integrated HIV Care NCT00317460	Yale University	Phase 4
Completed	Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories NCT00247572	New River Pharmaceuticals	Phase 2
Completed	Re-Entry MTC for Offenders With MICA Disorders NCT00249756	National Development and Research Institutes, Inc.	N/A
Completed	Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) NCT00798538	Yale University	Phase 4
Terminated	Cognitive Remediation in Early Substance Abuse Treatment NCT00334217	US Department of Veterans Affairs	N/A
Completed	A Brief Community Linkage Intervention for Dually Diagnosed Individuals NCT00137267	US Department of Veterans Affairs	N/A
Completed	Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder NCT00218725	University of Pennsylvania	Phase 1
Completed	Voucher-Based Incentives in a Prevention Setting NCT00607269	Friends Research Institute, Inc.	Phase 2 / Phase 3
Completed	Addition of Naltrexone to Methadone Taper NCT00135759	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Effectiveness of Bupropion in Treating Marijuana Dependent Individuals NCT00142870	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Skills Based Counseling for Adherence and Depression in HIV+ Methadone Patients - 1 NCT00218634	Massachusetts General Hospital	N/A
Unknown	Step'n Out: A Multisite Trial of Collaborative Behavioral Management for Drug-Involved Parolees NCT00302575	National Institute on Drug Abuse (NIDA)	N/A
Completed	Job-Seekers Training for Patients With Drug Dependence - 1 NCT00102362	Johns Hopkins University	Phase 3
Completed	Cognitive Therapy for PTSD in Addiction Treatment NCT00685451	Dartmouth-Hitchcock Medical Center	Phase 1 / Phase 2
Completed	Transitional Case Management Study NCT00264329	University of California, Los Angeles	Phase 3
Completed	Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse NCT00108407	US Department of Veterans Affairs	N/A
Completed	Pilot Clinical Trial of Computer-based Motivational Intervention - 1 NCT00230022	Wayne State University	Phase 1
Completed	Motivational Interviewing to Acutely Admitted Psychiatric Patients With Comorbid Substance Use NCT00184223	Norwegian University of Science and Technology	N/A
Completed	Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders NCT00438685	Medical University of South Carolina	Phase 1
Completed	Effectiveness of ATMX in Treating Adolescents With ADHD and SUD NCT00218322	Massachusetts General Hospital	Phase 4
Completed	Treatment of Comorbid Depression and Substance Abuse in Young People NCT00232284	Dan Lubman	Phase 2
Withdrawn	GHB Withdrawal Symptoms and Effectiveness of Treatment With Lorazepam Versus Pentobarbital - 1 NCT00123578	University of California, Los Angeles	Phase 1 / Phase 2
Completed	Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Postt NCT00118534	US Department of Veterans Affairs	N/A
Completed	Effects of Fatty Acid Supplementation on Substance Dependent Individuals NCT00312455	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Medical Office Intervention for Adolescent Drug Use NCT00229983	Boston Children's Hospital	Phase 2
Completed	Prescription Opioid Effects in Abusers Versus Non-Abusers NCT00158184	New York State Psychiatric Institute	Phase 2
Completed	Brief Intervention in Substance Use in Adolescent Psychiatric Patients NCT00694226	Hospital Clinic of Barcelona	N/A
Completed	Neurobiology and Pharmacokinets of Acute MDMA Administration NCT01148342	National Institute on Drug Abuse (NIDA)	Phase 1
Completed	Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs NCT00137306	US Department of Veterans Affairs	Phase 4
Completed	Women's Treatment for Trauma and Substance Use Disorders - 1 NCT00078156	New York State Psychiatric Institute	Phase 3
Completed	Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11 NCT00015301	National Institute on Drug Abuse (NIDA)	Phase 4
Completed	Motivational Enhancement for Spanish Speaking Individuals - 1 NCT00078169	Yale University	Phase 3
Completed	Quetiapine for Cocaine Use and Cravings NCT00232336	Seattle Institute for Biomedical and Clinical Research	Phase 4
Completed	Motivational Enhancement Therapy to Improve Treatment Utilization in Pregnant Substance Users - 1 NCT00078143	University of Cincinnati	Phase 3
Completed	Adolescent Drug and HIV Prevention in South Africa NCT00336180	Penn State University	Phase 2 / Phase 3
Completed	Transplant and Addiction Project (TAP) - 1 NCT00249652	St. Luke's-Roosevelt Hospital Center	Phase 1 / Phase 2
Completed	The Effects of Nutritional Supplementation and Drug Abuse on HIV NCT00149656	Florida International University	N/A
Completed	Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users NCT00194480	National Institute on Drug Abuse (NIDA)	Phase 4
Completed	Middle School to High School Transition Project: Depression and Substance Abuse Prevention NCT00071513	University of Washington	Phase 1
Completed	Effectiveness of Self-Help for Dually-Diagnosed Persons - 1 NCT00218582	National Institute on Drug Abuse (NIDA)	Phase 1 / Phase 2
Completed	The Women's Recovery Group Study: Stage I Trial NCT00230100	Mclean Hospital	Phase 1
Completed	Telephone Enhancement Procedure for Continuing Care - 1 NCT00067171	Duke University	Phase 3
Completed	Family Intervention for Mental Illness and Substance Abuse NCT00043693	Dartmouth-Hitchcock Medical Center	N/A
Completed	Interactive Motivational Media for Perinatal Drug Abuse - 3 NCT00230048	Wayne State University	Phase 2
Completed	Colorado Women's TC Project NCT00249561	National Development and Research Institutes, Inc.	Phase 1 / Phase 2
Unknown	Psychotherapy Enhancement for Therapeutic Community (TC) Retention - 1 NCT00086398	National Institute on Drug Abuse (NIDA)	Phase 2
Unknown	A Behavioral Trial for the Treatment of Methamphetamine Dependence. - 1 NCT00033124	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Reserpine for the Treatment of Cocaine Dependence - 1 NCT00033033	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine) NCT00895804	University Hospital, Basel, Switzerland	Phase 1
Completed	A Study of Cabergoline for the Treatment of Cocaine Dependence - 1 NCT00033111	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Zinc Therapy in HIV Infected Individuals Who Abuse Drugs NCT00149552	Florida International University	N/A
Completed	Motivational Enhancement to Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substan NCT00032981	Yale University	Phase 3
Completed	Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics. - 1 NCT00033020	Johns Hopkins University	Phase 3
Completed	Motivational Incentives for Enhanced Drug Abuse Recovery: Drug Free Clinics - 1 NCT00033007	Johns Hopkins University	Phase 3
Completed	Motivational Interviewing to Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substa NCT00032994	Yale University	Phase 3
Completed	Substance Dependent Teens - Impact of Treating Depression Study 1 - 1 NCT00061113	National Institute on Drug Abuse (NIDA)	Phase 4
Completed	Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users NCT00228007	Butler Hospital	Phase 3
Completed	Integrated Intervention for Substance Abusers With Depressive Disorders NCT00018655	VA Office of Research and Development	Phase 2
Completed	Cognitive Behavioral Therapy Combined With Antidepressants to Reduce HIV Risk and Drug Relapse Among Depressed NCT00183768	Butler Hospital	Phase 3
Completed	Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14 NCT00015340	National Institute on Drug Abuse (NIDA)	Phase 4
Completed	Multimodal Treatment Study of Children With Attention Deficit and Hyperactivity Disorder (MTA) NCT00000388	NYU Langone Health	Phase 4
Completed	Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13 NCT00000261	University of Chicago	Phase 2
Completed	Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16 NCT00000264	University of Chicago	N/A
Completed	Dextroamphetamine as an Adjunct in Cocaine Treatment - 1 NCT00000304	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Subjective Effects of Nitrous Oxide in Dental Patients - 17 NCT00000265	University of Chicago	—
Completed	Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12 NCT00000260	University of Chicago	N/A
Completed	Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Diso NCT00015223	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9 NCT00000274	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Coc NCT00158288	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Modeling Impaired Judgement in Cocaine Abusers - 6 NCT00015236	National Institute on Drug Abuse (NIDA)	Phase 4
Completed	Nefazodone in the Treatment of Cocaine Dependence and Depression - 4 NCT00015210	Boston Medical Center	Phase 2
Completed	Prepulse Inhibition of Startle in Cocaine Dependence - 7 NCT00015249	National Institute on Drug Abuse (NIDA)	Phase 1
Completed	Effects of Combined Alcohol and Nitrous Oxide Intake - 15 NCT00000263	University of Chicago	N/A
Completed	Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1 NCT00000352	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2 NCT00015041	National Institute on Drug Abuse (NIDA)	Phase 1
Completed	Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14 NCT00000262	University of Chicago	N/A

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