NCT04404348

Cognitive Rehabilitation for Opioid Abuse-related Cognitive Impairment

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Oklahoma State University Center for Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Research has consistently found that cognitive impairment is common in persons with a history of substance abuse. The most commonly identified impairments across all substances are in attentional and working memory functioning and executive functioning; opioid-specific research finds that memory is an additional area of common impairment. Initial research in applying cognitive rehabilitation methods to substance abuse have shown it to be helpful overall. To develop a cognitive rehabilitation intervention that is effective for opioid abuse, this study will adapt a cognitive training program that has been shown to be effective in other patient groups. Patients in a residential opioid-abuse treatment program will undergo a cognitive evaluation and then be assigned to receive the 4-week cognitive intervention or the 4-week placebo control arm. It is expected that the intervention group will show greater gains on the cognitive post test and will have higher rated treatment adherence and opioid treatment program completion rates.

Conditions

• Substance-Related Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive Training	Exercises used will be: Mind Bender, Divided Attention, Freeze Frame, Mixed Signals, Target Tracker, To Do List.
BEHAVIORAL	Placebo Control	Games are drawn from the set of research control games provided by Posit Science-Brain HQ.

Timeline

• Start date: 2020-03-06
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2020-05-27
• Last updated: 2020-09-18

Locations

1 site across 1 country: United States