NCT00249652

Transplant and Addiction Project (TAP) - 1

Drug Treatment for Transplant Candidates

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: St. Luke's-Roosevelt Hospital Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay "clean and sober" both prior and following transplant surgery.

Detailed description

Participants who need a liver or renal transplant and who are ineligible due to current or recent (past 6 months) alcohol and/or other drug abuse are being recruited from the transplant programs at St. Luke's-Roosevelt Hospital Center (renal), Columbia Presbyterian Hospital (renal/liver) and Virginia Commonwealth University Medical Center (liver). Baseline and follow-up computer-assisted assessments and structured clinical interviews along with collection of biological samples (urine, hair) will occur in the transplant clinics; however, phone counseling sessions originate at St. Luke's. Participants are randomly assigned to one of two treatments: (1) usual care (no phone counseling) or (2) usual care + counseling. The telephone counseling sessions are designed to help participants become motivated to remain abstinent and improve other health behaviors such as sleep or stress management.

Conditions

• End Stage Liver Disease
• End Stage Renal Disease
• Substance-Related Disorders

Interventions

Type	Name	Description
BEHAVIORAL	TAP	12-session motivational interviewing-based telephone intervention.
OTHER	TAU	The usual care group will receive the same medical services they would otherwise receive if they were not in this study.

Timeline

• Start date: 2003-09-01
• Primary completion: 2009-06-01
• Completion: 2009-09-01
• First posted: 2005-11-07
• Last updated: 2015-04-14

Locations

3 sites across 1 country: United States