Clinical Trials Directory

Trials / Terminated

TerminatedNCT00430573

Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use

Placebo-Controlled Evaluation of the Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Boston University Charles River Campus · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This study examines whether isolated doses of d-cycloserine enhance the efficacy of an exposure-based cognitive-behavioral treatment for chronic and treatment refractory substance dependence.

Detailed description

This is a placebo-controlled trial of the efficacy of 50mg d-cycloserine or matching pill placebo for enhancing the efficacy of CBT.

Conditions

Interventions

TypeNameDescription
DRUGD-cycloserineSingle dosage of D-cycloserine is given prior to each of 6 sessions of CBT-IC treatment (sessions 5-10)
DRUGPlaceboSingle dosage of placebo is given prior to each of 6 sessions of CBT-IC treatment (sessions 5-10)

Timeline

Start date
2007-02-01
Primary completion
2009-06-01
Completion
2009-06-01
First posted
2007-02-02
Last updated
2018-05-17
Results posted
2018-05-17

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT00430573. Inclusion in this directory is not an endorsement.