NCT00149656

The Effects of Nutritional Supplementation and Drug Abuse on HIV

HIV Disease, Drug Abuse, and Nutrient Therapy in Botswana

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 878 (actual)
• Sponsor: Florida International University · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this trial is to determine whether supplementation with multivitamins and selenium will delay disease progression in HIV infected individuals in Botswana. The study will also assess how drug abuse modifies the effect of nutritional supplementation on HIV disease progression.

Detailed description

Botswana has the highest rates of HIV infection in the world. In addition, drug abuse has become an emerging problem in Botswana. Past research suggests that multivitamin and selenium supplementation slows the progression of HIV disease. The purpose of this trial is to evaluate the effectiveness of supplementation with multivitamins and selenium in HIV infected individuals in Botswana. This trial will last 2 years. Participants will be randomly assigned to 4 groups: a combination of multivitamins with selenium, multivitamins alone, selenium alone, or placebo.

Conditions

• HIV Infections
• Substance-Related Disorders

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Multivitamins	dietary supplement of multivitamins
DIETARY_SUPPLEMENT	Selenium	dietary supplement of selenium only
OTHER	Placebo	placebo pill

Timeline

• Start date: 2003-06-01
• Primary completion: 2010-07-01
• Completion: 2013-04-01
• First posted: 2005-09-08
• Last updated: 2013-04-29

Locations

1 site across 1 country: Botswana